IMP

Process View

Homo sapiens

15 genes annotated in human

negative regulation of behavior

Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of behavior"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of behavior" (in gray)

Name	Description	Probability	Func Analog Organism
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.916	Mouse
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.885	Mouse
JAG1	jagged 1	0.810
CCR5	chemokine (C-C motif) receptor 5	0.791
TEK	TEK tyrosine kinase, endothelial	0.767
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.738	Mouse
DPP4	dipeptidyl-peptidase 4	0.503
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.475
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.387	Mouse
INSR	insulin receptor	0.301	Fly
CCL4	chemokine (C-C motif) ligand 4	0.295	Human
ADORA2A	adenosine A2a receptor	0.275
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.262
CCL5	chemokine (C-C motif) ligand 5	0.189	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.177
CXCL9	chemokine (C-X-C motif) ligand 9	0.165
FGA	fibrinogen alpha chain	0.134
CCL2	chemokine (C-C motif) ligand 2	0.110
TGFB1	transforming growth factor, beta 1	0.096
VEGFA	vascular endothelial growth factor A	0.095
PSG4	pregnancy specific beta-1-glycoprotein 4	0.073
CCL13	chemokine (C-C motif) ligand 13	0.070	Human
PSG5	pregnancy specific beta-1-glycoprotein 5	0.061	Mouse
IDE	insulin-degrading enzyme	0.052
GHR	growth hormone receptor	0.049
CCL8	chemokine (C-C motif) ligand 8	0.047	Human
CFH	complement factor H	0.043
IRS1	insulin receptor substrate 1	0.042
PSG3	pregnancy specific beta-1-glycoprotein 3	0.038
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.036
ITGB1BP3	integrin beta 1 binding protein 3	0.035
IL1B	interleukin 1, beta	0.035
DPT	dermatopontin	0.034
PSG9	pregnancy specific beta-1-glycoprotein 9	0.034	Mouse
VCAM1	vascular cell adhesion molecule 1	0.031
CRH	corticotropin releasing hormone	0.029
CCL3	chemokine (C-C motif) ligand 3	0.027	Human
FGFR1	fibroblast growth factor receptor 1	0.027
FGG	fibrinogen gamma chain	0.025
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.024
IRS2	insulin receptor substrate 2	0.024
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.024	Human
TGFB3	transforming growth factor, beta 3	0.023
PSG1	pregnancy specific beta-1-glycoprotein 1	0.023
DLL1	delta-like 1 (Drosophila)	0.022
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.022
PTPRB	protein tyrosine phosphatase, receptor type, B	0.022
MYLK2	myosin light chain kinase 2	0.022
C7	complement component 7	0.022
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.021
CCL19	chemokine (C-C motif) ligand 19	0.021	Human
GRB10	growth factor receptor-bound protein 10	0.021
CXCL10	chemokine (C-X-C motif) ligand 10	0.021
CPE	carboxypeptidase E	0.021
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.020
APOE	apolipoprotein E	0.020
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.020
IGF2R	insulin-like growth factor 2 receptor	0.019
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.019
C1S	complement component 1, s subcomponent	0.018
CXCL11	chemokine (C-X-C motif) ligand 11	0.018
CCL21	chemokine (C-C motif) ligand 21	0.018
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.018
FZD1	frizzled homolog 1 (Drosophila)	0.018
VCAN	versican	0.018
PSG6	pregnancy specific beta-1-glycoprotein 6	0.017	Mouse
DCN	decorin	0.017
IGFBP5	insulin-like growth factor binding protein 5	0.017
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.016
CCR7	chemokine (C-C motif) receptor 7	0.016
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.016
RGS1	regulator of G-protein signaling 1	0.015
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.015
UBD	ubiquitin D	0.014
PSG7	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	0.014
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.014
DARC	Duffy blood group, chemokine receptor	0.014
JAG2	jagged 2	0.013
CFI	complement factor I	0.013
NOTCH1	notch 1	0.013
IL6	interleukin 6 (interferon, beta 2)	0.013
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.013
IFNG	interferon, gamma	0.013
VSIG4	V-set and immunoglobulin domain containing 4	0.013
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.013	Worm Fly
PPP5C	protein phosphatase 5, catalytic subunit	0.013
MAML1	mastermind-like 1 (Drosophila)	0.012
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
FGB	fibrinogen beta chain	0.012	Human
C1R	complement component 1, r subcomponent	0.012
CCL11	chemokine (C-C motif) ligand 11	0.012	Human
IL10	interleukin 10	0.012
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.011	Fly
ITGA1	integrin, alpha 1	0.011
CCL7	chemokine (C-C motif) ligand 7	0.011	Human
ANGPT1	angiopoietin 1	0.011	Human
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.011	Mouse
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.011
CD83	CD83 molecule	0.011
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.010
PGF	placental growth factor	0.010
SELE	selectin E	0.010