IMP
Process View
development of secondary sexual characteristics
The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "development of secondary sexual characteristics"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Esr1 | estrogen receptor 1 (alpha) | 0.971 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.715 | ||
| Pax8 | paired box gene 8 | 0.577 | ||
| Pax2 | paired box gene 2 | 0.334 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.272 | Mouse | |
| Stat5b | signal transducer and activator of transcription 5B | 0.230 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.114 | Mouse | |
| Ar | androgen receptor | 0.114 | ||
| Lepr | leptin receptor | 0.095 | ||
| Kit | kit oncogene | 0.078 | ||
| Irf9 | interferon regulatory factor 9 | 0.064 | ||
| Bax | BCL2-associated X protein | 0.058 | ||
| Lhx1 | LIM homeobox protein 1 | 0.057 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.047 | ||
| Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.045 | ||
| Trp53 | transformation related protein 53 | 0.043 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.041 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.040 | Mouse | |
| Kl | klotho | 0.040 | ||
| Ret | ret proto-oncogene | 0.038 | ||
| Rxra | retinoid X receptor alpha | 0.037 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.037 | ||
| Prlr | prolactin receptor | 0.034 | ||
| Lep | leptin | 0.034 | ||
| Rarg | retinoic acid receptor, gamma | 0.034 | ||
| Ghr | growth hormone receptor | 0.033 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.032 | ||
| Rarb | retinoic acid receptor, beta | 0.032 | ||
| Wnt4 | wingless-related MMTV integration site 4 | 0.031 | Mouse | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.031 | Mouse | |
| Ncoa3 | nuclear receptor coactivator 3 | 0.030 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.030 | ||
| Pten | phosphatase and tensin homolog | 0.028 | ||
| Il6st | interleukin 6 signal transducer | 0.027 | ||
| Drd2 | dopamine receptor D2 | 0.026 | ||
| Foxf2 | forkhead box F2 | 0.026 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.025 | ||
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.025 | ||
| Tgfa | transforming growth factor alpha | 0.025 | ||
| Duox2 | dual oxidase 2 | 0.024 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.024 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.023 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.022 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.022 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.020 | ||
| Wfikkn2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.019 | ||
| Rara | retinoic acid receptor, alpha | 0.018 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.018 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.017 | ||
| Foxp3 | forkhead box P3 | 0.017 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.017 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.017 | ||
| Foxc1 | forkhead box C1 | 0.016 | ||
| Tg | thyroglobulin | 0.016 | ||
| Foxi1 | forkhead box I1 | 0.016 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.016 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.016 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.015 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.015 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.015 | ||
| Stat2 | signal transducer and activator of transcription 2 | 0.015 | Mouse | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.015 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.015 | ||
| Fgf10 | fibroblast growth factor 10 | 0.014 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.014 | Mouse | |
| Lyst | lysosomal trafficking regulator | 0.013 | ||
| Fosl2 | fos-like antigen 2 | 0.013 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.013 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.012 | ||
| Lhx3 | LIM homeobox protein 3 | 0.011 | ||
| Gpd2 | glycerol phosphate dehydrogenase 2, mitochondrial | 0.011 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.011 | ||
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.011 | ||
| Fgf8 | fibroblast growth factor 8 | 0.011 | ||
| Kiss1r | KISS1 receptor | 0.011 | ||
| Pgr | progesterone receptor | 0.011 | ||
| Inhbb | inhibin beta-B | 0.011 | ||
| Wnt10b | wingless related MMTV integration site 10b | 0.010 | Mouse | |
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.010 | Mouse | |
| Trim21 | tripartite motif-containing 21 | 0.010 | ||
| Wfikkn1 | WAP, FS, Ig, KU, and NTR-containing protein 1 | 0.010 | ||
| Pxn | paxillin | 0.010 | ||
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.010 |