IMP

Process View

Mus musculus

3 genes annotated in mouse

positive regulation of skeletal muscle fiber development

Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of skeletal muscle fiber development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of skeletal muscle fiber development" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	1.000
Bak1	BCL2-antagonist/killer 1	0.962	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.908
Trp53	transformation related protein 53	0.884
Bax	BCL2-associated X protein	0.880	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.842
Pax3	paired box gene 3	0.806
Myf6	myogenic factor 6	0.756	Mouse
En1	engrailed 1	0.723
Myoz1	myozenin 1	0.537
Bcl2	B-cell leukemia/lymphoma 2	0.527
Mybph	myosin binding protein H	0.457
Myf5	myogenic factor 5	0.421	Mouse
Pax7	paired box gene 7	0.333
Myog	myogenin	0.283
Vegfa	vascular endothelial growth factor A	0.279
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.236
Tbx15	T-box 15	0.204
Wt1	Wilms tumor 1 homolog	0.189
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.166
Shox2	short stature homeobox 2	0.147
Gdnf	glial cell line derived neurotrophic factor	0.131
Smad3	MAD homolog 3 (Drosophila)	0.122
Kit	kit oncogene	0.115
Myod1	myogenic differentiation 1	0.106	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.098
Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	0.089
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.080
Tcrb	T-cell receptor beta chain	0.072
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.072
Kera	keratocan	0.067
Tbx1	T-box 1	0.064
Pitx1	paired-like homeodomain transcription factor 1	0.054
Ebf3	early B-cell factor 3	0.050
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.050
Eya1	eyes absent 1 homolog (Drosophila)	0.049
Notch2	Notch gene homolog 2 (Drosophila)	0.047
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.045
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.044
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.044
Commd4	COMM domain containing 4	0.043
Ebf2	early B-cell factor 2	0.043
Matn3	matrilin 3	0.043
Tnnt3	troponin T3, skeletal, fast	0.041
Isl1	ISL1 transcription factor, LIM/homeodomain	0.039
Cav3	caveolin 3	0.036
Tnni2	troponin I, skeletal, fast 2	0.036
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.035
Pax2	paired box gene 2	0.034
Bcl2l1	BCL2-like 1	0.033	Mouse
Col11a1	collagen, type XI, alpha 1	0.032
Hoxc4	homeobox C4	0.031
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.030
Dlk1	delta-like 1 homolog (Drosophila)	0.030
Mecom	MDS1 and EVI1 complex locus	0.028
Ncoa3	nuclear receptor coactivator 3	0.028
Ly6h	lymphocyte antigen 6 complex, locus H	0.027
Myoc	myocilin	0.025
Hoxb3	homeobox B3	0.024
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.024
Hrc	histidine rich calcium binding protein	0.023
Fbxo32	F-box protein 32	0.023
Fgf10	fibroblast growth factor 10	0.022
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.022
Gli3	GLI-Kruppel family member GLI3	0.022
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.022
Mfn2	mitofusin 2	0.021
Myom2	myomesin 2	0.021
Hoxc8	homeobox C8	0.021
Hoxa9	homeobox A9	0.019
Tnni1	troponin I, skeletal, slow 1	0.018
Foxd1	forkhead box D1	0.018
Emid2	EMI domain containing 2	0.018
Casq1	calsequestrin 1	0.018
Pbx1	pre B-cell leukemia transcription factor 1	0.018
Tnnc2	troponin C2, fast	0.018
Arpc4	actin related protein 2/3 complex, subunit 4	0.018
Was	Wiskott-Aldrich syndrome homolog (human)	0.018
Prrx1	paired related homeobox 1	0.017
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.017
Foxd3	forkhead box D3	0.017
Eif3d	eukaryotic translation initiation factor 3, subunit D	0.016
Krt2	keratin 2	0.016
Otor	otoraplin	0.016
Pax8	paired box gene 8	0.016
Capn6	calpain 6	0.016
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.016
Hoxa2	homeobox A2	0.015
Col9a1	collagen, type IX, alpha 1	0.014
Insm1	insulinoma-associated 1	0.014
Neurog2	neurogenin 2	0.014
Ret	ret proto-oncogene	0.014
Arpc3	actin related protein 2/3 complex, subunit 3	0.014
Fitm1	fat storage-inducing transmembrane protein 1	0.013
Hmga2	high mobility group AT-hook 2	0.013
Cyp2b19	cytochrome P450, family 2, subfamily b, polypeptide 19	0.013
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.013
Lyst	lysosomal trafficking regulator	0.013
Tnip1	TNFAIP3 interacting protein 1	0.013
Epyc	epiphycan	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013
Prol1	proline rich, lacrimal 1	0.012
Rxra	retinoid X receptor alpha	0.012
Ldb3	LIM domain binding 3	0.012
Nphs2	nephrosis 2 homolog, podocin (human)	0.012
Myl1	myosin, light polypeptide 1	0.012
Phox2b	paired-like homeobox 2b	0.012
Ryr1	ryanodine receptor 1, skeletal muscle	0.011
Art1	ADP-ribosyltransferase 1	0.011
Myot	myotilin	0.011
Hoxd8	homeobox D8	0.011
Acvr2b	activin receptor IIB	0.011
Twist1	twist homolog 1 (Drosophila)	0.011
Bid	BH3 interacting domain death agonist	0.011
Hoxa4	homeobox A4	0.010
Hoxc5	homeobox C5	0.010
Col19a1	collagen, type XIX, alpha 1	0.010
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.010
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.010