IMP
Process View
proximal distal pattern formation involved in nephron development
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "proximal distal pattern formation involved in nephron development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.999 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.997 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.986 | ||
| Sox2 | SRY-box containing gene 2 | 0.979 | ||
| Shh | sonic hedgehog | 0.919 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.836 | ||
| Pax2 | paired box gene 2 | 0.806 | ||
| Nog | noggin | 0.700 | ||
| Foxg1 | forkhead box G1 | 0.690 | ||
| Lhx1 | LIM homeobox protein 1 | 0.644 | ||
| Irx1 | Iroquois related homeobox 1 (Drosophila) | 0.641 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.622 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.551 | ||
| Rb1 | retinoblastoma 1 | 0.535 | ||
| Tcfap2c | transcription factor AP-2, gamma | 0.437 | ||
| Lhx9 | LIM homeobox protein 9 | 0.398 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.394 | ||
| Fgf8 | fibroblast growth factor 8 | 0.392 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.324 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.320 | Mouse | |
| Pax6 | paired box gene 6 | 0.275 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.260 | ||
| Jag1 | jagged 1 | 0.257 | ||
| Lhx5 | LIM homeobox protein 5 | 0.226 | ||
| Irx5 | Iroquois related homeobox 5 (Drosophila) | 0.184 | Mouse | |
| En1 | engrailed 1 | 0.150 | ||
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.143 | ||
| Lhx3 | LIM homeobox protein 3 | 0.141 | ||
| Foxc1 | forkhead box C1 | 0.118 | ||
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.117 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.113 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.112 | ||
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.104 | ||
| Gsc | goosecoid homeobox | 0.102 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.101 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.101 | ||
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.083 | ||
| Hoxd11 | homeobox D11 | 0.068 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.066 | ||
| Uncx | UNC homeobox | 0.064 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.063 | ||
| Irx2 | Iroquois related homeobox 2 (Drosophila) | 0.063 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.061 | ||
| Rarg | retinoic acid receptor, gamma | 0.058 | ||
| Mnx1 | motor neuron and pancreas homeobox 1 | 0.055 | ||
| Wnt6 | wingless-related MMTV integration site 6 | 0.054 | ||
| Tbx1 | T-box 1 | 0.049 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.049 | ||
| Hmx3 | H6 homeobox 3 | 0.048 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.047 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.046 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.045 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.044 | ||
| Fgf15 | fibroblast growth factor 15 | 0.044 | ||
| Pax3 | paired box gene 3 | 0.044 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.042 | ||
| Tbx5 | T-box 5 | 0.038 | ||
| Wt1 | Wilms tumor 1 homolog | 0.036 | ||
| Gas1 | growth arrest specific 1 | 0.034 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.033 | ||
| Hoxa13 | homeobox A13 | 0.032 | ||
| Smo | smoothened homolog (Drosophila) | 0.031 | ||
| Msx1 | homeobox, msh-like 1 | 0.031 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.031 | ||
| Efna2 | ephrin A2 | 0.030 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.030 | ||
| Tbx3 | T-box 3 | 0.029 | ||
| Hoxd13 | homeobox D13 | 0.029 | ||
| Phlda2 | pleckstrin homology-like domain, family A, member 2 | 0.028 | ||
| Hoxd3 | homeobox D3 | 0.027 | ||
| Hmx1 | H6 homeobox 1 | 0.027 | ||
| Hoxa2 | homeobox A2 | 0.026 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.026 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.025 | ||
| Zfp503 | zinc finger protein 503 | 0.024 | ||
| Akr7a5 | aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) | 0.024 | ||
| Id1 | inhibitor of DNA binding 1 | 0.022 | ||
| Fgf18 | fibroblast growth factor 18 | 0.021 | ||
| Hoxa7 | homeobox A7 | 0.021 | ||
| Neurog1 | neurogenin 1 | 0.020 | ||
| Hoxd1 | homeobox D1 | 0.020 | ||
| Gata6 | GATA binding protein 6 | 0.020 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.019 | ||
| Bnc1 | basonuclin 1 | 0.018 | ||
| Sox17 | SRY-box containing gene 17 | 0.017 | ||
| Wnt1 | wingless-related MMTV integration site 1 | 0.017 | ||
| Gpc3 | glypican 3 | 0.017 | ||
| Efna4 | ephrin A4 | 0.017 | ||
| Sema3b | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.017 | ||
| Rara | retinoic acid receptor, alpha | 0.017 | ||
| Hes3 | hairy and enhancer of split 3 (Drosophila) | 0.016 | Mouse | |
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.016 | ||
| Hoxb2 | homeobox B2 | 0.016 | ||
| Pvrl1 | poliovirus receptor-related 1 | 0.015 | ||
| Krt14 | keratin 14 | 0.015 | ||
| Krt15 | keratin 15 | 0.015 | ||
| Crabp2 | cellular retinoic acid binding protein II | 0.014 | ||
| Sema6c | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | 0.014 | ||
| Grik3 | glutamate receptor, ionotropic, kainate 3 | 0.014 | ||
| Tbx2 | T-box 2 | 0.014 | ||
| BC024139 | cDNA sequence BC024139 | 0.014 | ||
| Cpz | carboxypeptidase Z | 0.013 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.013 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.013 | ||
| Sim2 | single-minded homolog 2 (Drosophila) | 0.012 | ||
| Fgf10 | fibroblast growth factor 10 | 0.012 | ||
| Foxd2 | forkhead box D2 | 0.012 | ||
| Hnf1b | HNF1 homeobox B | 0.012 | ||
| Eya2 | eyes absent 2 homolog (Drosophila) | 0.012 | ||
| Hsd11b2 | hydroxysteroid 11-beta dehydrogenase 2 | 0.011 | ||
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.011 | ||
| Foxc2 | forkhead box C2 | 0.011 | ||
| Prrx2 | paired related homeobox 2 | 0.011 | ||
| Hs6st3 | heparan sulfate 6-O-sulfotransferase 3 | 0.011 | ||
| Ly6g6d | lymphocyte antigen 6 complex, locus G6D | 0.011 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.011 | ||
| Six2 | sine oculis-related homeobox 2 homolog (Drosophila) | 0.011 | ||
| Clic3 | chloride intracellular channel 3 | 0.010 | ||
| Fgf3 | fibroblast growth factor 3 | 0.010 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.010 | ||
| Fbn2 | fibrillin 2 | 0.010 | ||
| Gata3 | GATA binding protein 3 | 0.010 | ||
| Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.010 |