IMP

Process View

Mus musculus

0 genes annotated in mouse

limb girdle muscular dystrophy

DOID:11724

A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "limb girdle muscular dystrophy" (in gray)

Name	Description	Probability	Func Analog Organism
Dmd	dystrophin, muscular dystrophy	0.997
Col4a1	collagen, type IV, alpha 1	0.667
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.491
Hnrnpd	heterogeneous nuclear ribonucleoprotein D	0.448
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.431
Cav3	caveolin 3	0.230
Anxa1	annexin A1	0.212
Ttn	titin	0.211
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.113
Art1	ADP-ribosyltransferase 1	0.103
Ldb3	LIM domain binding 3	0.089
Anxa2	annexin A2	0.086
Fkrp	fukutin related protein	0.085
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.078
Large	like-glycosyltransferase	0.076
B3gnt1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1	0.075
Yipf7	Yip1 domain family, member 7	0.061
Fktn	fukutin	0.058
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.056
Hrc	histidine rich calcium binding protein	0.054
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.052
Dag1	dystroglycan 1	0.051	Human
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.046
Nos3	nitric oxide synthase 3, endothelial cell	0.045
Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.038
Gja1	gap junction protein, alpha 1	0.037
Des	desmin	0.035
Srsf6	serine/arginine-rich splicing factor 6	0.033
Lmna	lamin A	0.031	Human
Sdc4	syndecan 4	0.031
Snta1	syntrophin, acidic 1	0.031
Myo18a	myosin XVIIIA	0.030
S100a6	S100 calcium binding protein A6 (calcyclin)	0.028
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.028	Human
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.027
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.027
Mstn	myostatin	0.026
Bag3	BCL2-associated athanogene 3	0.026
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.025
Alpk3	alpha-kinase 3	0.025
Myo1c	myosin IC	0.024
Xirp1	xin actin-binding repeat containing 1	0.024
Tns1	tensin 1	0.023
Ewsr1	Ewing sarcoma breakpoint region 1	0.022
Creld2	cysteine-rich with EGF-like domains 2	0.022
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.022
Tnnc1	troponin C, cardiac/slow skeletal	0.022
Kif1c	kinesin family member 1C	0.020
Fibin	fin bud initiation factor homolog (zebrafish)	0.019
2310046A06Rik	RIKEN cDNA 2310046A06 gene	0.019
Itgb1bp2	integrin beta 1 binding protein 2	0.019
Slc35b1	solute carrier family 35, member B1	0.018
Iqcc	IQ motif containing C	0.018
Dsc3	desmocollin 3	0.017
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.017
Nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.017
Plec	plectin	0.017	Human
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.016
Casq1	calsequestrin 1	0.016
Ank	progressive ankylosis	0.016
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.016
Tnnt3	troponin T3, skeletal, fast	0.016
Nrap	nebulin-related anchoring protein	0.016
Myoz2	myozenin 2	0.016
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.015
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.015
Manf	mesencephalic astrocyte-derived neurotrophic factor	0.015
Myom2	myomesin 2	0.015
Sh3pxd2b	SH3 and PX domains 2B	0.015
Sgcb	sarcoglycan, beta (dystrophin-associated glycoprotein)	0.015	Human
Lamc1	laminin, gamma 1	0.015
Hspb8	heat shock protein 8	0.015
Usp13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.015
Dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.015
D17Wsu104e	DNA segment, Chr 17, Wayne State University 104, expressed	0.015
Actn2	actinin alpha 2	0.014
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.014
Pfn2	profilin 2	0.014
Hnrnpa3	heterogeneous nuclear ribonucleoprotein A3	0.014
Csrp3	cysteine and glycine-rich protein 3	0.014
Egfr	epidermal growth factor receptor	0.014
Jup	junction plakoglobin	0.014
Tmem208	transmembrane protein 208	0.013
Anxa11	annexin A11	0.013
Eif5	eukaryotic translation initiation factor 5	0.013
Krt81	keratin 81	0.013
Jph2	junctophilin 2	0.013
Ski	ski sarcoma viral oncogene homolog (avian)	0.013
Ckmt2	creatine kinase, mitochondrial 2	0.013
Srpk3	serine/arginine-rich protein specific kinase 3	0.013
Flnc	filamin C, gamma	0.012
Nae1	NEDD8 activating enzyme E1 subunit 1	0.012
Idua	iduronidase, alpha-L-	0.011
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.011
Hdac4	histone deacetylase 4	0.011
Sun1	Sad1 and UNC84 domain containing 1	0.011
Steap3	STEAP family member 3	0.011
Srsf11	serine/arginine-rich splicing factor 11	0.011
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.011
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.011
Arhgap21	Rho GTPase activating protein 21	0.011
Sync	syncoilin	0.011
Dtna	dystrobrevin alpha	0.011
Kremen1	kringle containing transmembrane protein 1	0.011
Cox8b	cytochrome c oxidase, subunit VIIIb	0.011
Popdc2	popeye domain containing 2	0.011
Mtap4	microtubule-associated protein 4	0.011
Phlda3	pleckstrin homology-like domain, family A, member 3	0.010
Utrn	utrophin	0.010
Hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.010
Mef2d	myocyte enhancer factor 2D	0.010
Txlnb	taxilin beta	0.010
Ik	IK cytokine	0.010
Srsf5	serine/arginine-rich splicing factor 5	0.010