IMP

Process View

Mus musculus

7 genes annotated in mouse

Multi-species View

regulation of complement activation

GO:0030449

Any process that modulates the frequency, rate or extent of complement activation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of complement activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of complement activation" (in gray)

Name	Description	Probability	Func Analog Organism
F9	coagulation factor IX	0.627
C1ra	complement component 1, r subcomponent A	0.425
Apoe	apolipoprotein E	0.375
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.365
Apcs	serum amyloid P-component	0.336
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.267
Cp	ceruloplasmin	0.242
Saa4	serum amyloid A 4	0.241
Pzp	pregnancy zone protein	0.236	Mouse
Kng1	kininogen 1	0.191
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.179
Mrpl3	mitochondrial ribosomal protein L3	0.172
Gc	group specific component	0.171
Hrg	histidine-rich glycoprotein	0.161
Cfh	complement component factor h	0.158
Dcn	decorin	0.157
Timm10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.152
C1s	complement component 1, s subcomponent	0.146
C9	complement component 9	0.143	Mouse
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.129
Akr1c6	aldo-keto reductase family 1, member C6	0.127
Mug2	murinoglobulin 2	0.122
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.116
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.116
Mbl2	mannose-binding lectin (protein C) 2	0.113
Lum	lumican	0.112
Hc	hemolytic complement	0.109	Mouse
Mup3	major urinary protein 3	0.109
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.109
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.106
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.105
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.103
Otc	ornithine transcarbamylase	0.098
Egfr	epidermal growth factor receptor	0.091
Rdh7	retinol dehydrogenase 7	0.080
Cfhr1	complement factor H-related 1	0.074
Fgg	fibrinogen gamma chain	0.071
Crp	C-reactive protein, pentraxin-related	0.071
Ahsg	alpha-2-HS-glycoprotein	0.065
Cfi	complement component factor i	0.064
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.063
Fgb	fibrinogen beta chain	0.062
C2	complement component 2 (within H-2S)	0.058
Plg	plasminogen	0.057
Fga	fibrinogen alpha chain	0.056
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.056
Tmem176b	transmembrane protein 176B	0.053
Il1r1	interleukin 1 receptor, type I	0.053
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.051
Lyz2	lysozyme 2	0.051
Gm4788	predicted gene 4788	0.050	Rat
Orm2	orosomucoid 2	0.050
Lipc	lipase, hepatic	0.050
Tdo2	tryptophan 2,3-dioxygenase	0.050
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.048
Mup5	major urinary protein 5	0.046
Ces1c	carboxylesterase 1C	0.046
C1qc	complement component 1, q subcomponent, C chain	0.046
Apof	apolipoprotein F	0.045
Rnase4	ribonuclease, RNase A family 4	0.044
F2	coagulation factor II	0.044
Fas	Fas (TNF receptor superfamily member 6)	0.043
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.042
Mbl1	mannose-binding lectin (protein A) 1	0.042
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.041
Ces3a	carboxylesterase 3A	0.041
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.040
Cfhr2	complement factor H-related 2	0.039	Rat
Ambp	alpha 1 microglobulin/bikunin	0.039
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.038
Spna1	spectrin alpha 1	0.038
Afm	afamin	0.038
Hgd	homogentisate 1, 2-dioxygenase	0.037
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.037
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.037
Lbp	lipopolysaccharide binding protein	0.037
C1rb	complement component 1, r subcomponent B	0.035
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.034	Human
F12	coagulation factor XII (Hageman factor)	0.032
C8a	complement component 8, alpha polypeptide	0.030	Mouse
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.030
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.029
Mrc1	mannose receptor, C type 1	0.029
Ikbkg	inhibitor of kappaB kinase gamma	0.029
C4b	complement component 4B (Childo blood group)	0.029	Mouse
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.029
C3	complement component 3	0.028
Apoa1	apolipoprotein A-I	0.028
Lect2	leukocyte cell-derived chemotaxin 2	0.028
Cd28	CD28 antigen	0.027
F13b	coagulation factor XIII, beta subunit	0.027	Mouse
Apoh	apolipoprotein H	0.026	Mouse
F11	coagulation factor XI	0.026
Aadac	arylacetamide deacetylase (esterase)	0.026
Hao1	hydroxyacid oxidase 1, liver	0.026
Casp12	caspase 12	0.025
Klkb1	kallikrein B, plasma 1	0.025
Pros1	protein S (alpha)	0.025
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.024
Mug1	murinoglobulin 1	0.024	Mouse
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.023
Cd302	CD302 antigen	0.023
C8b	complement component 8, beta polypeptide	0.022	Mouse
Proc	protein C	0.022
Hpx	hemopexin	0.022
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.022
F10	coagulation factor X	0.022
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.022
Alb	albumin	0.021
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.021
Apon	apolipoprotein N	0.021
Pipox	pipecolic acid oxidase	0.020
Atad3a	ATPase family, AAA domain containing 3A	0.020
Inpp5d	inositol polyphosphate-5-phosphatase D	0.019
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.019
Cps1	carbamoyl-phosphate synthetase 1	0.019
Mup10	major urinary protein 10	0.019
Il10	interleukin 10	0.019
Fxyd1	FXYD domain-containing ion transport regulator 1	0.019
Rag1	recombination activating gene 1	0.019
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.019
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.018
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.018
Creb3l3	cAMP responsive element binding protein 3-like 3	0.018
Gpr182	G protein-coupled receptor 182	0.018
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.017
Cml2	camello-like 2	0.017
Uox	urate oxidase	0.017
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.017
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.016
Ms4a4d	membrane-spanning 4-domains, subfamily A, member 4D	0.016
Fmo1	flavin containing monooxygenase 1	0.015
Ttr	transthyretin	0.015
Agxt	alanine-glyoxylate aminotransferase	0.015
ND6	NADH dehydrogenase subunit 6	0.015
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.015
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.015
Inhbe	inhibin beta E	0.015
Saa2	serum amyloid A 2	0.015
Apoa5	apolipoprotein A-V	0.015
Rab27a	RAB27A, member RAS oncogene family	0.015
G6pc	glucose-6-phosphatase, catalytic	0.015
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.014
Orm1	orosomucoid 1	0.014
F8	coagulation factor VIII	0.014
Colec12	collectin sub-family member 12	0.014
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.014
Igf1	insulin-like growth factor 1	0.013
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.013
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.013
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.013
Mup4	major urinary protein 4	0.013
Aadat	aminoadipate aminotransferase	0.013
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.013
Apom	apolipoprotein M	0.013
Hp	haptoglobin	0.013
Keg1	kidney expressed gene 1	0.013
Mat1a	methionine adenosyltransferase I, alpha	0.013
Ogn	osteoglycin	0.013
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.013
Clec4f	C-type lectin domain family 4, member f	0.012
Apoc4	apolipoprotein C-IV	0.012
Fabp1	fatty acid binding protein 1, liver	0.012
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.012
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.012
Prodh2	proline dehydrogenase (oxidase) 2	0.012
Nnmt	nicotinamide N-methyltransferase	0.012
Akr1c21	aldo-keto reductase family 1, member C21	0.012
Avpr1a	arginine vasopressin receptor 1A	0.011
Il6	interleukin 6	0.011
Akap4	A kinase (PRKA) anchor protein 4	0.011
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.011
Apob	apolipoprotein B	0.011
Upp2	uridine phosphorylase 2	0.011
Sepp1	selenoprotein P, plasma, 1	0.011
Cox18	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.011
Slc17a2	solute carrier family 17 (sodium phosphate), member 2	0.011
Rarres2	retinoic acid receptor responder (tazarotene induced) 2	0.011
Fbp1	fructose bisphosphatase 1	0.011
Cfb	complement factor B	0.011
Tfpi2	tissue factor pathway inhibitor 2	0.010
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.010
Slc3a1	solute carrier family 3, member 1	0.010
C4bp	complement component 4 binding protein	0.010	Human Mouse
F5	coagulation factor V	0.010
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.010
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.010
Spp1	secreted phosphoprotein 1	0.010