IMP
Process View
sterol biosynthetic process
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "sterol biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Cyp51 | cytochrome P450, family 51 | 1.000 | Yeast Rat | |
| Dhcr7 | 7-dehydrocholesterol reductase | 0.987 | ||
| Mvd | mevalonate (diphospho) decarboxylase | 0.984 | ||
| Lss | lanosterol synthase | 0.984 | Human Yeast | |
| Idi1 | isopentenyl-diphosphate delta isomerase | 0.971 | ||
| Sqle | squalene epoxidase | 0.971 | Yeast | |
| Ldlr | low density lipoprotein receptor | 0.968 | ||
| Hmgcs1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 0.945 | ||
| Apoa1 | apolipoprotein A-I | 0.676 | ||
| Dhcr24 | 24-dehydrocholesterol reductase | 0.658 | ||
| Sc4mol | sterol-C4-methyl oxidase-like | 0.560 | Yeast | |
| 0610007P14Rik | RIKEN cDNA 0610007P14 gene | 0.502 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.450 | ||
| Fdps | farnesyl diphosphate synthetase | 0.436 | ||
| Nsdhl | NAD(P) dependent steroid dehydrogenase-like | 0.395 | ||
| Hsd17b7 | hydroxysteroid (17-beta) dehydrogenase 7 | 0.371 | ||
| Fasn | fatty acid synthase | 0.369 | ||
| Acat2 | acetyl-Coenzyme A acetyltransferase 2 | 0.358 | ||
| Aacs | acetoacetyl-CoA synthetase | 0.255 | ||
| Tm7sf2 | transmembrane 7 superfamily member 2 | 0.249 | Yeast | |
| Slc25a1 | solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 | 0.213 | ||
| Pcyt2 | phosphate cytidylyltransferase 2, ethanolamine | 0.179 | ||
| Stard4 | StAR-related lipid transfer (START) domain containing 4 | 0.165 | ||
| Acly | ATP citrate lyase | 0.164 | ||
| Sc5d | sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) | 0.155 | Yeast | |
| Apoe | apolipoprotein E | 0.135 | Human Mouse | |
| Npc1 | Niemann Pick type C1 | 0.131 | ||
| Mvk | mevalonate kinase | 0.123 | Human | |
| Rdh11 | retinol dehydrogenase 11 | 0.111 | ||
| Scd2 | stearoyl-Coenzyme A desaturase 2 | 0.111 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.101 | ||
| Apob | apolipoprotein B | 0.082 | ||
| Srebf2 | sterol regulatory element binding factor 2 | 0.081 | Mouse | |
| Cyb5b | cytochrome b5 type B | 0.063 | ||
| Elovl6 | ELOVL family member 6, elongation of long chain fatty acids (yeast) | 0.056 | ||
| Pmvk | phosphomevalonate kinase | 0.049 | ||
| Fads2 | fatty acid desaturase 2 | 0.047 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.044 | ||
| Slc9a3r1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.043 | ||
| Tmem97 | transmembrane protein 97 | 0.043 | ||
| Cyp26c1 | cytochrome P450, family 26, subfamily c, polypeptide 1 | 0.039 | ||
| Hsd17b12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.034 | ||
| Aldob | aldolase B, fructose-bisphosphate | 0.033 | ||
| Hmgcr | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 0.033 | ||
| Insig1 | insulin induced gene 1 | 0.026 | ||
| Tmem64 | transmembrane protein 64 | 0.024 | ||
| Fdft1 | farnesyl diphosphate farnesyl transferase 1 | 0.024 | ||
| Srebf1 | sterol regulatory element binding transcription factor 1 | 0.023 | ||
| Fads1 | fatty acid desaturase 1 | 0.023 | ||
| Ebag9 | estrogen receptor-binding fragment-associated gene 9 | 0.023 | ||
| Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.022 | ||
| Reep6 | receptor accessory protein 6 | 0.021 | ||
| Rnf11 | ring finger protein 11 | 0.019 | ||
| Sigmar1 | sigma non-opioid intracellular receptor 1 | 0.018 | ||
| Hsd17b2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.017 | ||
| Slc4a4 | solute carrier family 4 (anion exchanger), member 4 | 0.017 | ||
| Lyz2 | lysozyme 2 | 0.016 | ||
| Srf | serum response factor | 0.016 | ||
| Apoa2 | apolipoprotein A-II | 0.015 | ||
| Pex3 | peroxisomal biogenesis factor 3 | 0.015 | ||
| Pgd | phosphogluconate dehydrogenase | 0.014 | ||
| Apoc3 | apolipoprotein C-III | 0.014 | ||
| Slc31a1 | solute carrier family 31, member 1 | 0.014 | ||
| F2 | coagulation factor II | 0.014 | ||
| Tmem135 | transmembrane protein 135 | 0.013 | ||
| Cflar | CASP8 and FADD-like apoptosis regulator | 0.013 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.012 | ||
| Grb10 | growth factor receptor bound protein 10 | 0.012 | ||
| Hnf4a | hepatic nuclear factor 4, alpha | 0.012 | ||
| Tkt | transketolase | 0.012 | ||
| Scarb1 | scavenger receptor class B, member 1 | 0.012 | ||
| Rnf103 | ring finger protein 103 | 0.011 | ||
| Lcat | lecithin cholesterol acyltransferase | 0.011 | ||
| Ppara | peroxisome proliferator activated receptor alpha | 0.011 | ||
| Eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 0.011 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.011 | ||
| Fga | fibrinogen alpha chain | 0.011 | ||
| Ambp | alpha 1 microglobulin/bikunin | 0.011 | ||
| Ndfip1 | Nedd4 family interacting protein 1 | 0.011 | ||
| Foxa2 | forkhead box A2 | 0.011 | ||
| Pank3 | pantothenate kinase 3 | 0.010 | ||
| Tecr | trans-2,3-enoyl-CoA reductase | 0.010 | ||
| Apoa4 | apolipoprotein A-IV | 0.010 | Mouse | |
| Apom | apolipoprotein M | 0.010 | ||
| Fgg | fibrinogen gamma chain | 0.010 | ||
| Sec14l2 | SEC14-like 2 (S. cerevisiae) | 0.010 | Rat |