Process View
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "g protein coupled purinergic nucleotide receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.534 | ||
| P2ry12 | purinergic receptor P2Y, G-protein coupled 12 | 0.482 | ||
| Ly86 | lymphocyte antigen 86 | 0.407 | ||
| P2ry13 | purinergic receptor P2Y, G-protein coupled 13 | 0.347 | Mouse Rat | |
| March1 | membrane-associated ring finger (C3HC4) 1 | 0.327 | ||
| Clec7a | C-type lectin domain family 7, member a | 0.327 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.286 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.253 | ||
| Pld4 | phospholipase D family, member 4 | 0.153 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.152 | ||
| Clec5a | C-type lectin domain family 5, member a | 0.151 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.127 | ||
| Plek | pleckstrin | 0.122 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.111 | ||
| Aif1 | allograft inflammatory factor 1 | 0.100 | ||
| Mrc1 | mannose receptor, C type 1 | 0.099 | ||
| Hpgds | hematopoietic prostaglandin D synthase | 0.095 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.093 | ||
| Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D | 0.086 | ||
| Gpr34 | G protein-coupled receptor 34 | 0.085 | Mouse | |
| Mpeg1 | macrophage expressed gene 1 | 0.080 | ||
| Ctss | cathepsin S | 0.078 | ||
| Clec4a3 | C-type lectin domain family 4, member a3 | 0.070 | ||
| Cysltr1 | cysteinyl leukotriene receptor 1 | 0.068 | ||
| Rgs18 | regulator of G-protein signaling 18 | 0.065 | ||
| Tlr13 | toll-like receptor 13 | 0.060 | ||
| 5430427O19Rik | RIKEN cDNA 5430427O19 gene | 0.059 | ||
| Lpxn | leupaxin | 0.059 | ||
| Cd83 | CD83 antigen | 0.058 | ||
| Cd86 | CD86 antigen | 0.057 | ||
| Sash3 | SAM and SH3 domain containing 3 | 0.054 | ||
| Bank1 | B-cell scaffold protein with ankyrin repeats 1 | 0.054 | ||
| Cd33 | CD33 antigen | 0.053 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.050 | ||
| Cd53 | CD53 antigen | 0.048 | ||
| Cd200r1 | CD200 receptor 1 | 0.045 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.045 | ||
| Sirpa | signal-regulatory protein alpha | 0.044 | ||
| Havcr2 | hepatitis A virus cellular receptor 2 | 0.043 | ||
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.041 | ||
| Cd84 | CD84 antigen | 0.036 | ||
| Arhgap15 | Rho GTPase activating protein 15 | 0.035 | ||
| Fcgr3 | Fc receptor, IgG, low affinity III | 0.035 | ||
| Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 | 0.035 | ||
| Evi2a | ecotropic viral integration site 2a | 0.032 | ||
| Duoxa1 | dual oxidase maturation factor 1 | 0.032 | ||
| Alox5ap | arachidonate 5-lipoxygenase activating protein | 0.031 | ||
| Tifab | TRAF-interacting protein with forkhead-associated domain, family member B | 0.030 | ||
| Abcg3 | ATP-binding cassette, sub-family G (WHITE), member 3 | 0.029 | ||
| Clec4b1 | C-type lectin domain family 4, member b1 | 0.029 | ||
| Tcfec | transcription factor EC | 0.029 | ||
| Cd300ld | CD300 molecule-like family member d | 0.029 | ||
| Stap1 | signal transducing adaptor family member 1 | 0.029 | ||
| A630033H20Rik | RIKEN cDNA A630033H20 gene | 0.027 | ||
| Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.026 | ||
| Cxcr6 | chemokine (C-X-C motif) receptor 6 | 0.024 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.024 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.022 | ||
| Cd48 | CD48 antigen | 0.021 | ||
| Abcd2 | ATP-binding cassette, sub-family D (ALD), member 2 | 0.021 | ||
| Cd300lb | CD300 antigen like family member B | 0.021 | ||
| Krt15 | keratin 15 | 0.021 | ||
| Omg | oligodendrocyte myelin glycoprotein | 0.021 | ||
| Ms4a7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.021 | ||
| Gatm | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.019 | ||
| Igsf6 | immunoglobulin superfamily, member 6 | 0.019 | ||
| AF251705 | cDNA sequence AF251705 | 0.019 | ||
| Timd4 | T-cell immunoglobulin and mucin domain containing 4 | 0.019 | ||
| Slc46a2 | solute carrier family 46, member 2 | 0.018 | ||
| Sirpb1a | signal-regulatory protein beta 1A | 0.017 | ||
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.017 | Mouse | |
| Slamf9 | SLAM family member 9 | 0.017 | ||
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.017 | ||
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.016 | ||
| Rnase6 | ribonuclease, RNase A family, 6 | 0.016 | ||
| Tlr8 | toll-like receptor 8 | 0.016 | ||
| Gm885 | predicted gene 885 | 0.016 | ||
| Sprr1b | small proline-rich protein 1B | 0.016 | ||
| Cd69 | CD69 antigen | 0.015 | ||
| Ms4a6c | membrane-spanning 4-domains, subfamily A, member 6C | 0.015 | ||
| Lce1d | late cornified envelope 1D | 0.015 | ||
| Gm6377 | predicted gene 6377 | 0.015 | ||
| P2ry10 | purinergic receptor P2Y, G-protein coupled 10 | 0.015 | ||
| Vcam1 | vascular cell adhesion molecule 1 | 0.015 | ||
| Il33 | interleukin 33 | 0.015 | ||
| Fyb | FYN binding protein | 0.015 | ||
| Fcgr4 | Fc receptor, IgG, low affinity IV | 0.015 | ||
| Gjb6 | gap junction protein, beta 6 | 0.014 | ||
| Gpr65 | G-protein coupled receptor 65 | 0.014 | ||
| Tmem54 | transmembrane protein 54 | 0.014 | ||
| BC013712 | cDNA sequence BC013712 | 0.013 | ||
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.013 | ||
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.013 | ||
| Trim29 | tripartite motif-containing 29 | 0.013 | ||
| Il18 | interleukin 18 | 0.013 | ||
| Rgs10 | regulator of G-protein signalling 10 | 0.013 | ||
| Lce1f | late cornified envelope 1F | 0.012 | ||
| Nts | neurotensin | 0.012 | ||
| Calcb | calcitonin-related polypeptide, beta | 0.012 | ||
| Tcl1b3 | T-cell leukemia/lymphoma 1B, 3 | 0.012 | ||
| Slc14a1 | solute carrier family 14 (urea transporter), member 1 | 0.012 | ||
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.012 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.012 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.011 | ||
| Lpcat2 | lysophosphatidylcholine acyltransferase 2 | 0.011 | ||
| Cdh17 | cadherin 17 | 0.011 | ||
| Tifa | TRAF-interacting protein with forkhead-associated domain | 0.011 | ||
| Ptpro | protein tyrosine phosphatase, receptor type, O | 0.011 | ||
| BC035044 | cDNA sequence BC035044 | 0.011 | ||
| Prkcb | protein kinase C, beta | 0.011 | ||
| Gpr171 | G protein-coupled receptor 171 | 0.010 | Mouse | |
| Ppbp | pro-platelet basic protein | 0.010 | ||
| Lix1 | limb expression 1 homolog (chicken) | 0.010 | ||
| Fcrls | Fc receptor-like S, scavenger receptor | 0.010 |