IMP

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Rattus norvegicus

18 genes annotated in rat

regulation of excitatory postsynaptic membrane potential

Any process that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of excitatory postsynaptic membrane potential"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of excitatory postsynaptic membrane potential" (in gray)

Name	Description	Probability	Func Analog Organism
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.756
Dlg4	discs, large homolog 4 (Drosophila)	0.754
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.722
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.620	Mouse Rat
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.352
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.301
Dlg3	discs, large homolog 3 (Drosophila)	0.235	Rat
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.202
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.157
Nlgn2	neuroligin 2	0.146	Mouse Rat
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.144
Drd1a	dopamine receptor D1A	0.142
Syn1	synapsin I	0.135
Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.118	Mouse
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.118
Hpcal4	hippocalcin-like 4	0.116
Grm7	glutamate receptor, metabotropic 7	0.104
RGD1565859	RGD1565859	0.103
Prkcg	protein kinase C, gamma	0.100	Rat
Glp1r	glucagon-like peptide 1 receptor	0.097
Hrh3	histamine receptor H3	0.089
Unc5a	unc-5 homolog A (C. elegans)	0.086
Lin7b	lin-7 homolog b (C. elegans)	0.083
Foxg1	forkhead box G1	0.082
Shank1	SH3 and multiple ankyrin repeat domains 1	0.080	Mouse
Adra2c	adrenergic, alpha-2C-, receptor	0.073	Rat
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.070
Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	0.069
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.067
Shank2	SH3 and multiple ankyrin repeat domains 2	0.065
Accn2	amiloride-sensitive cation channel 2, neuronal	0.064
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.064
Bcan	brevican	0.063
Nfasc	neurofascin	0.062
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.061
Gna15	guanine nucleotide binding protein, alpha 15	0.061
Gria1	glutamate receptor, ionotropic, AMPA 1	0.058
Ifna1	interferon-alpha 1	0.058
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.057
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.057
Gjb5	gap junction protein, beta 5	0.056
Camkv	CaM kinase-like vesicle-associated	0.055
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.053
Prph2	peripherin 2	0.051
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.050
Chrm3	cholinergic receptor, muscarinic 3	0.049
RGD1564664	similar to LOC387763 protein	0.047
Nlgn3	neuroligin 3	0.047	Mouse Rat
Htr4	5-hydroxytryptamine (serotonin) receptor 4	0.046	Rat
Dbc1	deleted in bladder cancer 1 (human)	0.046
Acrv1	acrosomal vesicle protein 1	0.045
Myt1l	myelin transcription factor 1-like	0.044
Grm8	glutamate receptor, metabotropic 8	0.044
Prkca	protein kinase C, alpha	0.043	Rat
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1	0.043
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.043
Adora2a	adenosine A2a receptor	0.042
Nrxn2	neurexin 2	0.042
Baiap2	BAI1-associated protein 2	0.042
Strn	striatin, calmodulin binding protein	0.040
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.040
Cckbr	cholecystokinin B receptor	0.040
Nlgn1	neuroligin 1	0.039
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.039
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.038
Tacr1	tachykinin receptor 1	0.037
Cit	citron	0.037
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.037
Fgfr2	fibroblast growth factor receptor 2	0.036
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.036
Ncan	neurocan	0.036
Sp3	Sp3 transcription factor	0.036
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.034	Rat
Rasgrp1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.034
Sidt1	SID1 transmembrane family, member 1	0.034
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.034
Klk1c10	T-kininogenase	0.033
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.033
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.033
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.032
Egr3	early growth response 3	0.032
Stxbp2	syntaxin binding protein 2	0.032
Dlg2	discs, large homolog 2 (Drosophila)	0.032	Rat
Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	0.032
Cartpt	CART prepropeptide	0.032
Vip	vasoactive intestinal peptide	0.032
Gck	glucokinase	0.031
Sdk2	sidekick homolog 2 (chicken)	0.031
Drd3	dopamine receptor D3	0.031	Rat
Rgs14	regulator of G-protein signaling 14	0.031
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.031
Gad2	glutamate decarboxylase 2	0.030
Hpca	hippocalcin	0.030
Ppyr1	pancreatic polypeptide receptor 1	0.030
Musk	muscle, skeletal, receptor tyrosine kinase	0.030
Nmur2	neuromedin U receptor 2	0.030
Erc1	ELKS/RAB6-interacting/CAST family member 1	0.030
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.029
Grm5	glutamate receptor, metabotropic 5	0.029
Shox2	short stature homeobox 2	0.028
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.028
Smr3a	submaxillary gland androgen regulated protein 3A	0.028
Hist1h1a	histone cluster 1, H1a	0.028
Aqp2	aquaporin 2 (collecting duct)	0.028
Accn1	amiloride-sensitive cation channel 1, neuronal	0.028
Crhbp	corticotropin releasing hormone binding protein	0.028
Syt6	synaptotagmin VI	0.027
Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	0.027
Ppara	peroxisome proliferator activated receptor alpha	0.027
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.027
Stxbp1	syntaxin binding protein 1	0.026
Smad3	SMAD family member 3	0.025
LOC60591	calcium-activated potassium channel beta subunit	0.025
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.025
Cops7a	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.025
Grm6	glutamate receptor, metabotropic 6	0.025
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.024
Myo1d	myosin ID	0.024
Trim9	tripartite motif-containing 9	0.024
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.024
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.024	Rat
Clstn3	calsyntenin 3	0.024
Ptprz1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.023
Chrm5	cholinergic receptor, muscarinic 5	0.023
Prp15	proline-rich protein 15	0.023
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.023
Pnlip	pancreatic lipase	0.023
Arpp21	cAMP-regulated phosphoprotein 21	0.023
Neu2	sialidase 2 (cytosolic sialidase)	0.022
Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.022
Homer1	homer homolog 1 (Drosophila)	0.022
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.022
Rup2	urinary protein 2	0.022
Sstr5	somatostatin receptor 5	0.021	Rat
Csrnp2	cysteine-serine-rich nuclear protein 2	0.021
Vamp2	vesicle-associated membrane protein 2	0.021
Rab15	RAB15, member RAS oncogene family	0.021
Nrgn	neurogranin	0.021
Grik1	glutamate receptor, ionotropic, kainate 1	0.020
Barhl2	BarH-like homeobox 2	0.020
Nxph1	neurexophilin 1	0.020
Olr416	olfactory receptor 416	0.020
Phkg1	phosphorylase kinase, gamma 1	0.020
Grm1	glutamate receptor, metabotropic 1	0.020
Neurog3	neurogenin 3	0.020
Necab2	N-terminal EF-hand calcium binding protein 2	0.020
Dpf1	D4, zinc and double PHD fingers family 1	0.020
Itpka	inositol 1,4,5-trisphosphate 3-kinase A	0.020
Sept6	septin 6	0.019
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.019
Gabbr1	gamma-aminobutyric acid (GABA) B receptor 1	0.019
Sh3gl2	SH3-domain GRB2-like 2	0.019
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.019
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.019
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.019
Msx2	msh homeobox 2	0.019
Ghrhr	growth hormone releasing hormone receptor	0.019
Abcg4	ATP-binding cassette, subfamily G (WHITE), member 4	0.018
Tmem59l	transmembrane protein 59-like	0.018
Fgf14	fibroblast growth factor 14	0.018
Chrnb1	cholinergic receptor, nicotinic, beta 1 (muscle)	0.018
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.018
Psd	pleckstrin and Sec7 domain containing	0.018
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.018
Adra2a	adrenergic, alpha-2A-, receptor	0.017
Synpo	synaptopodin	0.017
Folh1	folate hydrolase 1	0.017
Prrx1	paired related homeobox 1	0.017
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.017
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.017
Clcn4-2	chloride channel 4-2	0.017
Ier5	immediate early response 5	0.017
Kcnip4	Kv channel interacting protein 4	0.016
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive	0.016
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.016
Gdnf	glial cell derived neurotrophic factor	0.016
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.016
Pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.016
Pex5l	peroxisomal biogenesis factor 5-like	0.016
Mos	Moloney sarcoma oncogene	0.016
Nrxn1	neurexin 1	0.016
Rgs9	regulator of G-protein signaling 9	0.015
Kctd13	potassium channel tetramerisation domain containing 13	0.015
Ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.015
Pcdhb12	protocadherin beta 12	0.015
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.015
Insrr	insulin receptor-related receptor	0.015
RGD1566085	similar to pyridoxal (pyridoxine, vitamin B6) kinase	0.015
Grifin	galectin-related inter-fiber protein	0.015
Ica1l	islet cell autoantigen 1-like	0.015
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.015
Trhr	thyrotropin releasing hormone receptor	0.015
Gpr12	G protein-coupled receptor 12	0.015
Olr1500	olfactory receptor 1500	0.015
Gpr173	G-protein coupled receptor 173	0.015
Crhr1	corticotropin releasing hormone receptor 1	0.015
Arhgap23	Rho GTPase activating protein 23	0.014
Vom2r53	vomeronasal 2 receptor, 53	0.014
Grin2d	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.014	Rat
Ar	androgen receptor	0.014
Eef2	eukaryotic translation elongation factor 2	0.014
Kcnip3	Kv channel interacting protein 3, calsenilin	0.014
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.014
RGD1304952	similar to RIKEN cDNA C530028O21 gene	0.014
Isl2	ISL LIM homeobox 2	0.014
Cd38	CD38 molecule	0.014
Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	0.013
Grp	gastrin releasing peptide	0.013
Csf1	colony stimulating factor 1 (macrophage)	0.013
Dgki	diacylglycerol kinase, iota	0.013
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.013	Rat
Aqp4	aquaporin 4	0.013
Il17re	interleukin 17 receptor E	0.013
Crhr2	corticotropin releasing hormone receptor 2	0.013
Ins2	insulin 2	0.013
Fam83f	family with sequence similarity 83, member F	0.013
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.013
Gabrd	gamma-aminobutyric acid (GABA) A receptor, delta	0.013
Cacng8	calcium channel, voltage-dependent, gamma subunit 8	0.013
Lhx5	LIM homeobox 5	0.013
Klra22	killer cell lectin-like receptor subfamily A, member 22	0.013
Sycn	syncollin	0.013
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.013
Dcc	deleted in colorectal carcinoma	0.012
Rims1	regulating synaptic membrane exocytosis 1	0.012	Mouse
Drd2	dopamine receptor D2	0.012	Rat
Olr1082	olfactory receptor 1082	0.012
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.012
Lgals4	lectin, galactoside-binding, soluble, 4	0.012
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.012
Ccr3	chemokine (C-C motif) receptor 3	0.012
Npy5r	neuropeptide Y receptor Y5	0.012
Acr	acrosin	0.012
Cyss	cystatin S	0.012
Pde2a	phosphodiesterase 2A, cGMP-stimulated	0.012
Cdc7	cell division cycle 7 homolog (S. cerevisiae)	0.012
Camk2d	calcium/calmodulin-dependent protein kinase II delta	0.012
Hnmt	histamine N-methyltransferase	0.012
Map3k9	mitogen-activated protein kinase kinase kinase 9	0.012
Grpr	gastrin releasing peptide receptor	0.011
Ppp2r5e	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.011
Neurod2	neurogenic differentiation 2	0.011
Mas1	MAS1 oncogene	0.011
Odf4	outer dense fiber of sperm tails 4	0.011
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.011
Akap1	A kinase (PRKA) anchor protein 1	0.011
Nefl	neurofilament, light polypeptide	0.011
Adora3	adenosine A3 receptor	0.011	Rat
Kalrn	kalirin, RhoGEF kinase	0.011
Syt17	synaptotagmin XVII	0.011
Adrb2	adrenergic, beta-2-, receptor, surface	0.011
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.011
Syn2	synapsin II	0.011
Sec23a	Sec23 homolog A (S. cerevisiae)	0.011
Akap5	A kinase (PRKA) anchor protein 5	0.011
Myo16	myosin XVI	0.011
Tulp1	tubby like protein 1	0.011
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.011	Rat
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.011
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.011
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.011
Syt5	synaptotagmin V	0.011
Sert1	Sertoli cell protein 1	0.011
Znf532	zinc finger protein 532	0.011
Hrh2	histamine receptor H 2	0.011	Rat
Fabp2	fatty acid binding protein 2, intestinal	0.011
Rabac1	Rab acceptor 1 (prenylated)	0.010
Sstr1	somatostatin receptor 1	0.010
N5	DNA binding protein N5	0.010
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.010
Mc5r	melanocortin 5 receptor	0.010
Nrcam	neuronal cell adhesion molecule	0.010
Gucy1a2	guanylate cyclase 1, soluble, alpha 2	0.010
Jdp2	Jun dimerization protein 2	0.010
Glra2	glycine receptor, alpha 2	0.010
Gfpt1	glutamine fructose-6-phosphate transaminase 1	0.010
Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)	0.010
Slc22a13	solute carrier family 22 (organic anion transporter), member 13	0.010
Syt10	synaptotagmin X	0.010
Gal	galanin prepropeptide	0.010
Adora1	adenosine A1 receptor	0.010
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010
Galr3	galanin receptor 3	0.010
Cntn1	contactin 1	0.010
Oprd1	opioid receptor, delta 1	0.010	Rat
Scg5	secretogranin V	0.010
Fibcd1	fibrinogen C domain containing 1	0.010
Syt13	synaptotagmin XIII	0.010
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.010
Syp	synaptophysin	0.010