IMP
Process View
positive regulation of necrotic cell death
Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of necrotic cell death"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mcpt8 | mast cell protease 8 | 0.628 | Rat | |
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.444 | ||
| Cma1 | chymase 1, mast cell | 0.300 | ||
| Cpa3 | carboxypeptidase A3, mast cell | 0.241 | ||
| Lgals3 | lectin, galactoside-binding, soluble, 3 | 0.176 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.151 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.130 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.107 | ||
| Gzmc | granzyme C | 0.081 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.080 | ||
| Il2rb | interleukin 2 receptor, beta | 0.071 | ||
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.059 | ||
| LOC100361706 | lambda-chain C1-region-like | 0.058 | ||
| Gzmb | granzyme B | 0.056 | ||
| LOC100361261 | rCG23560-like | 0.051 | ||
| Klrc2 | killer cell lectin-like receptor subfamily C, member 2 | 0.051 | ||
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 0.043 | ||
| Mcpt9 | mast cell protease 9 | 0.043 | Rat | |
| Mcpt10 | mast cell protease 10 | 0.040 | Rat | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.037 | ||
| S100a8 | S100 calcium binding protein A8 | 0.036 | ||
| Tcrb | T-cell receptor beta chain | 0.034 | ||
| Klrb1a | killer cell lectin-like receptor subfamily B, member 1A | 0.030 | ||
| Oas1b | 2-5 oligoadenylate synthetase 1B | 0.028 | ||
| RatNP-3b | defensin RatNP-3 precursor | 0.026 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.026 | ||
| Gzmf | granzyme F | 0.025 | Rat | |
| Syt4 | synaptotagmin IV | 0.025 | ||
| Krt1-5 | keratin complex 1, acidic, gene 5 | 0.023 | ||
| Cd247 | Cd247 molecule | 0.022 | ||
| Art2 | ADP-ribosyltransferase 2 | 0.022 | ||
| Tsx | testis specific X-linked gene | 0.022 | ||
| Cd2 | Cd2 molecule | 0.020 | ||
| RGD1564878 | similar to natural killer cell protease 7 | 0.020 | ||
| Serpinb5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.020 | ||
| Musk | muscle, skeletal, receptor tyrosine kinase | 0.020 | ||
| Hspb1 | heat shock protein 1 | 0.019 | ||
| Gfi1 | growth factor independent 1 transcription repressor | 0.019 | ||
| C6 | complement component 6 | 0.018 | ||
| Ncr3 | natural cytotoxicity triggering receptor 3 | 0.018 | ||
| PVR | poliovirus receptor | 0.018 | ||
| Capg | capping protein (actin filament), gelsolin-like | 0.018 | ||
| Hpgds | hematopoietic prostaglandin D synthase | 0.018 | ||
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.018 | ||
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.018 | ||
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.018 | ||
| Prm2 | protamine 2 | 0.017 | ||
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.017 | ||
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.017 | ||
| Cela1 | chymotrypsin-like elastase family, member 1 | 0.017 | ||
| Slc18a1 | solute carrier family 18 (vesicular monoamine), member 1 | 0.017 | ||
| LOC24906 | RoBo-1 | 0.017 | ||
| Clca4 | chloride channel accessory 4 | 0.017 | ||
| Hmox1 | heme oxygenase (decycling) 1 | 0.016 | ||
| Gcnt3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.016 | ||
| Cd151 | CD151 molecule (Raph blood group) | 0.016 | ||
| Tagln3 | transgelin 3 | 0.016 | ||
| Cd3d | CD3 molecule, delta | 0.016 | ||
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.016 | ||
| Gzmm | granzyme M (lymphocyte met-ase 1) | 0.016 | ||
| Plaur | plasminogen activator, urokinase receptor | 0.016 | ||
| Semg1 | semenogelin I | 0.016 | ||
| Bcl10 | B-cell CLL/lymphoma 10 | 0.016 | ||
| Spink1 | serine peptidase inhibitor, Kazal type 1 | 0.015 | ||
| Fabp4 | fatty acid binding protein 4, adipocyte | 0.015 | ||
| Tec | tec protein tyrosine kinase | 0.015 | ||
| Gzmk | granzyme K | 0.015 | Rat | |
| Dnase1l3 | deoxyribonuclease 1-like 3 | 0.015 | ||
| Zg16 | zymogen granule protein 16 | 0.015 | ||
| Grm8 | glutamate receptor, metabotropic 8 | 0.015 | ||
| LOC100360501 | ribonuclease inhibitor-like | 0.015 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.015 | ||
| Il6st | interleukin 6 signal transducer | 0.015 | ||
| Cd3g | CD3 molecule, gamma | 0.015 | ||
| Mcpt2 | mast cell protease 2 | 0.014 | Rat | |
| Tmigd1 | transmembrane and immunoglobulin domain containing 1 | 0.014 | ||
| Expi | extracellular proteinase inhibitor | 0.014 | ||
| Tnni2 | troponin I type 2 (skeletal, fast) | 0.014 | ||
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.014 | ||
| Rassf1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.013 | ||
| Prl3d4 | prolactin family 3, subfamily d, member 4 | 0.013 | ||
| Clec9a | C-type lectin domain family 9, member a | 0.013 | ||
| Cib1 | calcium and integrin binding 1 (calmyrin) | 0.013 | ||
| Gzma | granzyme A | 0.013 | Rat | |
| Tmem72 | transmembrane protein 72 | 0.012 | ||
| Alox15 | arachidonate 15-lipoxygenase | 0.012 | ||
| Anxa2 | annexin A2 | 0.012 | ||
| Hck | hemopoietic cell kinase | 0.012 | ||
| Il7r | interleukin 7 receptor | 0.012 | ||
| Syn1 | synapsin I | 0.012 | ||
| P22k15 | cystatin related protein 2 | 0.012 | ||
| Capn9 | calpain 9 | 0.012 | ||
| Klre1 | killer cell lectin-like receptor, family E, member 1 | 0.012 | ||
| Cd79b | Cd79b molecule, immunoglobulin-associated beta | 0.012 | ||
| Il18 | interleukin 18 | 0.012 | ||
| Fam3b | family with sequence similarity 3, member B | 0.012 | ||
| Gadd45a | growth arrest and DNA-damage-inducible, alpha | 0.012 | ||
| Prlh | prolactin releasing hormone | 0.012 | ||
| Ccl11 | chemokine (C-C motif) ligand 11 | 0.012 | ||
| Fosl1 | fos-like antigen 1 | 0.012 | ||
| Tnpo1 | transportin 1 | 0.011 | ||
| Ctsd | cathepsin D | 0.011 | ||
| Nppb | natriuretic peptide precursor B | 0.011 | ||
| Tnfrsf14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.011 | ||
| Ubd | ubiquitin D | 0.011 | ||
| Pttg1ip | pituitary tumor-transforming 1 interacting protein | 0.011 | ||
| Sdc1 | syndecan 1 | 0.011 | ||
| Opcml | opioid binding protein/cell adhesion molecule-like | 0.011 | ||
| Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.011 | ||
| Cd8a | CD8a molecule | 0.011 | ||
| Igsf6 | immunoglobulin superfamily, member 6 | 0.011 | ||
| Ifng | interferon gamma | 0.011 | ||
| Cmtm2a | CKLF-like MARVEL transmembrane domain containing 2A | 0.011 | ||
| Il10 | interleukin 10 | 0.011 | ||
| Stat4 | signal transducer and activator of transcription 4 | 0.011 | ||
| Ear11 | eosinophil-associated, ribonuclease A family, member 11 | 0.010 | ||
| Map4k1 | mitogen activated protein kinase kinase kinase kinase 1 | 0.010 | ||
| Zcchc6 | zinc finger, CCHC domain containing 6 | 0.010 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.010 | ||
| Aldh1a7 | aldehyde dehydrogenase family 1, subfamily A7 | 0.010 | ||
| Gata1 | GATA binding protein 1 | 0.010 | ||
| Col11a2 | collagen, type XI, alpha 2 | 0.010 | ||
| Fas | Fas (TNF receptor superfamily, member 6) | 0.010 | ||
| Oas1a | 2'-5' oligoadenylate synthetase 1A | 0.010 | ||
| Hbz | hemoglobin, zeta | 0.010 |