IMP

Process View

Rattus norvegicus

2 genes annotated in rat

response to high density lipoprotein particle

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to high density lipoprotein particle"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to high density lipoprotein particle" (in gray)

Name	Description	Probability	Func Analog Organism
Il1b	interleukin 1 beta	0.982
Cd14	CD14 molecule	0.965
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.868
Cxcl10	chemokine (C-X-C motif) ligand 10	0.860
Ccl3	chemokine (C-C motif) ligand 3	0.797	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.772
Cxcl2	chemokine (C-X-C motif) ligand 2	0.655
Ccl4	chemokine (C-C motif) ligand 4	0.624	Rat
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.583
Il6	interleukin 6	0.514
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.490
Gzmb	granzyme B	0.297
Timp1	TIMP metallopeptidase inhibitor 1	0.210
Cd44	Cd44 molecule	0.207
Gzmk	granzyme K	0.207
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.194
Reg3b	regenerating islet-derived 3 beta	0.181
Il1r2	interleukin 1 receptor, type II	0.143
Top2a	topoisomerase (DNA) II alpha	0.139
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.126
Hmox1	heme oxygenase (decycling) 1	0.118
Mmp12	matrix metallopeptidase 12	0.109
Plek	pleckstrin	0.107
Rgs1	regulator of G-protein signaling 1	0.106
Atf3	activating transcription factor 3	0.098
Ccl7	chemokine (C-C motif) ligand 7	0.087	Rat
Prf1	perforin 1 (pore forming protein)	0.084
Igsf6	immunoglobulin superfamily, member 6	0.082
Mmp3	matrix metallopeptidase 3	0.080
Icam1	intercellular adhesion molecule 1	0.079
Il1a	interleukin 1 alpha	0.073
Xcl1	chemokine (C motif) ligand 1	0.067	Rat
Jak2	Janus kinase 2	0.067
Neurl3	neuralized homolog 3 (Drosophila)	0.065
Tfpi2	tissue factor pathway inhibitor 2	0.063
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.063
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.059
Stx11	syntaxin 11	0.059
Ier3	immediate early response 3	0.053
Runx1	runt-related transcription factor 1	0.053
Il2rb	interleukin 2 receptor, beta	0.051
Plaur	plasminogen activator, urokinase receptor	0.048
Litaf	lipopolysaccharide-induced TNF factor	0.048
Nkg7	natural killer cell group 7 sequence	0.044
Ch25h	cholesterol 25-hydroxylase	0.040
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.039
Tlr2	toll-like receptor 2	0.038
Iqgap1	IQ motif containing GTPase activating protein 1	0.037
Fcn1	ficolin (collagen/fibrinogen domain containing) 1	0.037
Sele	selectin E	0.036
Rhoj	ras homolog gene family, member J	0.035
Serpinb2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.030
Steap1	six transmembrane epithelial antigen of the prostate 1	0.028
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.028
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.028
Adamts4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	0.027
Cd86	CD86 molecule	0.025
Plau	plasminogen activator, urokinase	0.025
Myc	myelocytomatosis oncogene	0.024
Ripk3	receptor-interacting serine-threonine kinase 3	0.024
Ccl5	chemokine (C-C motif) ligand 5	0.023
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.023
Mgst2	microsomal glutathione S-transferase 2	0.022
Ccr1	chemokine (C-C motif) receptor 1	0.022
LOC685020	similar to paired immunoglobin-like type 2 receptor alpha	0.021
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.021
Vcan	versican	0.021
Ccl20	chemokine (C-C motif) ligand 20	0.021	Rat
PVR	poliovirus receptor	0.021
Egr2	early growth response 2	0.020
Ripk2	receptor-interacting serine-threonine kinase 2	0.020
Tnfrsf26	tumor necrosis factor receptor superfamily, member 26	0.019
Cst7	cystatin F (leukocystatin)	0.019
Tlr7	toll-like receptor 7	0.018
Hpgds	hematopoietic prostaglandin D synthase	0.017
Spp1	secreted phosphoprotein 1	0.017
Fosl1	fos-like antigen 1	0.016
Plscr1	phospholipid scramblase 1	0.016
Mcpt8	mast cell protease 8	0.016
Rassf9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.016
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.016
Cldn4	claudin 4	0.016
Nox4	NADPH oxidase 4	0.016
Kdr	kinase insert domain receptor	0.015
Cd8a	CD8a molecule	0.015
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.015
Junb	jun B proto-oncogene	0.015
Tcrb	T-cell receptor beta chain	0.014
Il7r	interleukin 7 receptor	0.014
RT1-Bb	RT1 class II, locus Bb	0.014
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.013
Bst1	bone marrow stromal cell antigen 1	0.013
Ptgs2	prostaglandin-endoperoxide synthase 2	0.013
Mcm2	minichromosome maintenance complex component 2	0.013
Postn	periostin, osteoblast specific factor	0.013
Plod2	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2	0.012
Fst	follistatin	0.012
Arl5c	ADP-ribosylation factor-like 5C	0.012
Fas	Fas (TNF receptor superfamily, member 6)	0.011
Tchh	trichohyalin	0.011
Rnd1	Rho family GTPase 1	0.011
Rab32	RAB32, member RAS oncogene family	0.011
Casp1	caspase 1	0.011
Il4ra	interleukin 4 receptor, alpha	0.011
Gch1	GTP cyclohydrolase 1	0.010
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.010
S100a9	S100 calcium binding protein A9	0.010