IMP

Process View

Danio rerio

11 genes annotated in zebrafish

establishment or maintenance of epithelial cell apical basal polarity

Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment or maintenance of epithelial cell apical basal polarity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment or maintenance of epithelial cell apical basal polarity" (in gray)

Name	Description	Probability	Func Analog Organism
crb2a	crumbs homolog 2a	0.986
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.955
dag1	dystroglycan 1	0.849
csad	cysteine sulfinic acid decarboxylase	0.502
prkci	protein kinase C, iota	0.402
lrp2	low density lipoprotein-related protein 2	0.256
guca1c	guanylate cyclase activator 1C	0.170
cdh2	cadherin 2, neuronal	0.167
mstna	myostatin a	0.146
gro2	groucho 2	0.144
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.143
pitpnb	phosphotidylinositol transfer protein, beta	0.139
ythdf1	YTH domain family, member 1	0.124
scrib	scribbled homolog (Drosophila)	0.123	Worm
crx	cone-rod homeobox	0.106
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.104
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.097
si:dkey-97i18.2	si:dkey-97i18.2	0.096
mib	mind bomb	0.091
skia	nuclear oncoprotein skia	0.087
opn4x1	opsin 4x1	0.080
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.078
lama1	laminin, alpha 1	0.071
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.068
homez	homeodomain leucine zipper gene	0.068
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.067
dtng	dystrobrevin, gamma and dystrobrevin, gamma-like	0.065
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.064
pxn	paxillin	0.064
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.057
rras	related RAS viral (r-ras) oncogene homolog	0.057
lamb1a	laminin, beta 1a	0.056
ptprf	protein tyrosine phosphatase, receptor type, F	0.055
sall4	sal-like 4 (Drosophila)	0.054
fn1	fibronectin 1	0.053
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.053
zgc:63721	zgc:63721	0.052
cxadr	coxsackie virus and adenovirus receptor	0.050
frmd6	FERM domain containing 6	0.050	Zebrafish
fam43b	family with sequence similarity 43, member B	0.048
rp2	retinitis pigmentosa 2 (X-linked recessive)	0.048
bhmt	betaine-homocysteine methyltransferase	0.045
prickle1a	prickle-like 1 (Drosophila) a	0.041
sema3aa	semaphorin 3aa	0.040
slc4a4a	solute carrier family 4, member 4a	0.040
waca	WW domain containing adaptor with coiled-coil a	0.040
sb:cb472	sb:cb472	0.039
cntn1b	contactin 1b	0.039
zgc:110298	zgc:110298	0.037
sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.036
six4.3	sine oculis homeobox homolog 4.3	0.036
myf5	myogenic factor 5	0.036
perp	PERP, TP53 apoptosis effector	0.035
sdcbp	syndecan binding protein (syntenin)	0.033
enpp6	ectonucleotide pyrophosphatase/phosphodiesterase 6	0.033
tfec	transcription factor EC	0.033
hgfa	hepatocyte growth factor a	0.033
axin1	axin 1	0.032
LOC100003514	protein kinase C alpha type-like	0.032
crb3b	crumbs homolog 3b	0.032
nrxn1a	neurexin 1a	0.032
casz1	castor zinc finger 1	0.032
rtn4a	reticulon 4a	0.031
zgc:114199	zgc:114199	0.031
cast	calpastatin	0.031
prkcz	protein kinase C, zeta	0.031	Zebrafish
src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.031
si:ch211-272f3.4	si:ch211-272f3.4	0.030
krt8	keratin 8	0.029
apc	adenomatosis polyposis coli	0.029
arpc5b	actin related protein 2/3 complex, subunit 5B	0.028
vcl	vinculin	0.028
kif7	kinesin family member 7	0.027
LOC100331502	melanopsin-B-like	0.026
zfpl1	zinc finger protein-like 1	0.026
lman2	lectin, mannose-binding 2	0.026
zgc:153148	zgc:153148	0.026
lamc1	laminin, gamma 1	0.026
mxi1	max interacting protein	0.026
synj1	synaptojanin 1	0.025
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.025	Zebrafish
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.025
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.024
olfm1b	olfactomedin 1b	0.024
LOC100007758	novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)	0.023
ehd1	EH-domain containing 1	0.023
dopey1	dopey family member 1	0.023
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.023
tm9sf2	transmembrane 9 superfamily member 2	0.022
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.022
si:ch211-134j6.3	si:ch211-134j6.3	0.022
dlg1	discs, large (Drosophila) homolog 1	0.022
fgfrl1a	fibroblast growth factor receptor-like 1a	0.022
cyfip2	cytoplasmic FMR1 interacting protein 2	0.022
si:rp71-1p14.10	si:rp71-1p14.10	0.021
utrn	utrophin	0.021
ptk2.1	protein tyrosine kinase 2a	0.021
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.021	Fly
chm	choroideremia	0.021
crb3a	crumbs homolog 3a	0.021
dctn1a	dynactin 1a	0.020
sulf1	sulfatase 1	0.020
ilk	integrin linked kinase	0.020	Mouse
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.020
hgfb	hepatocyte growth factor b	0.020
has2	hyaluronan synthase 2	0.020
npepps	aminopeptidase puromycin sensitive	0.020
grk7a	G-protein-coupled receptor kinase 7a	0.020
im:7137555	im:7137555	0.019
lama2	laminin, alpha 2	0.019
chd7	chromodomain helicase DNA binding protein 7	0.019
smad2	MAD homolog 2 (Drosophila)	0.018
sb:cb560	sb:cb560	0.018
pkp2	plakophilin 2	0.018
zgc:195154	zgc:195154	0.018
vangl2	vang-like 2 (van gogh, Drosophila)	0.017
anxa5b	annexin A5b	0.016
c1qtnf4	C1q and tumor necrosis factor related protein 4	0.016
zgc:77439	zgc:77439	0.016
lmbr1l	limb region 1 like	0.016
dspa	desmoplakin a	0.015
sc:d0319	sc:d0319	0.015
sulf2l	sulfatase 2, like	0.015
zgc:92758	zgc:92758	0.015
oclna	occludin a	0.015
zgc:66100	zgc:66100	0.015
pcdh8	protocadherin 8	0.015
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.014
dusp4	dual specificity phosphatase 4	0.014
zgc:66385	zgc:66385	0.014
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.014
slc45a2	solute carrier family 45, member 2	0.014
robo2	roundabout homolog 2	0.014
rc3	rabconnectin 3	0.014
sb:cb730	sb:cb730	0.013
efemp2	EGF-containing fibulin-like extracellular matrix protein 2	0.013
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.013
pdlim1	PDZ and LIM domain 1 (elfin)	0.013
insrb	insulin receptor b	0.013
acvr1b	activin A receptor, type IB	0.013
opn4a	opsin 4a (melanopsin)	0.013
mpp6a	membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)	0.013	Zebrafish
lsr	lipolysis stimulated lipoprotein receptor	0.013
gab1	GRB2-associated binding protein 1	0.013
tpm1	tropomyosin 1 (alpha)	0.013
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.013
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.012
si:ch211-232m7.1	si:ch211-232m7.1	0.012
cldn12	claudin 12	0.012
fzd7a	frizzled homolog 7a	0.012
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.012
cdh6	cadherin 6	0.012
jam2a	junctional adhesion molecule 2a	0.012
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.012
xirp2b	xin actin-binding repeat containing 2b	0.012
gnsb	glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b	0.012
zgc:103586	zgc:103586	0.011
cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.011
capns1b	calpain, small subunit 1 b	0.011
mef2d	myocyte enhancer factor 2d	0.011
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.011
map3k4	mitogen activated protein kinase kinase kinase 4	0.011
zgc:101598	zgc:101598	0.011
nyx	nyctalopin	0.011
map2k4a	mitogen-activated protein kinase kinase 4a	0.011
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.011
ocrl	oculocerebrorenal syndrome of Lowe	0.011
zgc:56429	zgc:56429	0.011
plcg1	phospholipase C, gamma 1	0.011
ren	renin	0.011
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.011	Fly
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.011
si:ch211-284e13.2	si:ch211-284e13.2	0.011
crb1	crumbs homolog 1 (Drosophila)	0.011
zbtb22b	zinc finger and BTB domain containing 22b	0.011
pard3	par-3 partitioning defective 3 homolog (C. elegans)	0.011
iqgap1	IQ motif containing GTPase activating protein 1	0.010
trpa1a	transient receptor potential cation channel, subfamily A, member 1a	0.010
stil	TAL1 (SCL) interrupting locus	0.010
kif5c	kinesin family member 5C	0.010
pias4a	protein inhibitor of activated STAT, 4a	0.010
dmrt1	doublesex and mab-3 related transcription factor 1	0.010
cenph	centromere protein H	0.010
cadps2	Ca2+-dependent activator protein for secretion 2	0.010
wt1b	wilms tumor 1b	0.010
eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.010