The network for 'leukocyte migration involved in inflammatory response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leukocyte migration involved in inflammatory response

The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.

Name Description Probability Func Analog Organism
S100A6 S100 calcium binding protein A6 1.000
S100A8 S100 calcium binding protein A8 1.000
S100A9 S100 calcium binding protein A9 0.999
S100A4 S100 calcium binding protein A4 0.982
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.982
S100A11 S100 calcium binding protein A11 0.940
ANXA2 annexin A2 0.864
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.847
S100A14 S100 calcium binding protein A14 0.755
S100B S100 calcium binding protein B 0.726
S100A2 S100 calcium binding protein A2 0.574
FKBP4 FK506 binding protein 4, 59kDa 0.482
AREG amphiregulin 0.473
LGALS1 lectin, galactoside-binding, soluble, 1 0.397
S100A1 S100 calcium binding protein A1 0.326
AGER advanced glycosylation end product-specific receptor 0.287
TMSB10 thymosin beta 10 0.278
S100A10 S100 calcium binding protein A10 0.232
LGALS3 lectin, galactoside-binding, soluble, 3 0.184
EMP3 epithelial membrane protein 3 0.171
S100P S100 calcium binding protein P 0.144
ANXA1 annexin A1 0.111
S100A13 S100 calcium binding protein A13 0.086
TIMP1 TIMP metallopeptidase inhibitor 1 0.085
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.077
CSTA cystatin A (stefin A) 0.075
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.073
PF4 platelet factor 4 0.072
S100A12 S100 calcium binding protein A12 0.065
NCF2 neutrophil cytosolic factor 2 0.054
GORAB golgin, RAB6-interacting 0.053
JAM2 junctional adhesion molecule 2 0.052
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.048
IL1R2 interleukin 1 receptor, type II 0.047
LMNA lamin A/C 0.045
CLIC1 chloride intracellular channel 1 0.043
FPR1 formyl peptide receptor 1 0.040
CAPG capping protein (actin filament), gelsolin-like 0.037
CLEC4M C-type lectin domain family 4, member M 0.027
RRAS related RAS viral (r-ras) oncogene homolog 0.027
IGSF21 immunoglobin superfamily, member 21 0.026
C4BPA complement component 4 binding protein, alpha 0.026
SLPI secretory leukocyte peptidase inhibitor 0.023
PI3 peptidase inhibitor 3, skin-derived 0.021
CD14 CD14 molecule 0.021
HIPK2 homeodomain interacting protein kinase 2 0.020
HBB hemoglobin, beta 0.018
ANXA5 annexin A5 0.018
LCN2 lipocalin 2 0.017
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.015
FLNA filamin A, alpha 0.015
AHNAK AHNAK nucleoprotein 0.015
CD63 CD63 molecule 0.015
SFN stratifin 0.014
MXD1 MAX dimerization protein 1 0.014
TGFBI transforming growth factor, beta-induced, 68kDa 0.014
CRIP1 cysteine-rich protein 1 (intestinal) 0.013
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.013
CSTB cystatin B (stefin B) 0.013
C5AR1 complement component 5a receptor 1 0.013
FPR2 formyl peptide receptor 2 0.013
NPC2 Niemann-Pick disease, type C2 0.013
EFNA1 ephrin-A1 0.012
HSPB1 heat shock 27kDa protein 1 0.012
TSPO translocator protein (18kDa) 0.011
BTC betacellulin 0.011
TREM1 triggering receptor expressed on myeloid cells 1 0.011
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.011
KRT23 keratin 23 (histone deacetylase inducible) 0.011
GPR109B G protein-coupled receptor 109B 0.010
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.010
BST1 bone marrow stromal cell antigen 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.949
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.876
Ngp neutrophilic granule protein 0.353
Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) 0.350
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.304
Itgb3 integrin beta 3 0.302
Mpdz multiple PDZ domain protein 0.251
Pick1 protein interacting with C kinase 1 0.245
Camp cathelicidin antimicrobial peptide 0.206
Clec4d C-type lectin domain family 4, member d 0.199
Mmp8 matrix metallopeptidase 8 0.197
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.153
Tgfb2 transforming growth factor, beta 2 0.152
Hbegf heparin-binding EGF-like growth factor 0.136
Jag1 jagged 1 0.132
Efnb2 ephrin B2 0.127
C5ar1 complement component 5a receptor 1 0.112
Plaur plasminogen activator, urokinase receptor 0.109
Klf3 Kruppel-like factor 3 (basic) 0.108
Prnp prion protein 0.105
Lcn2 lipocalin 2 0.093
Chi3l3 chitinase 3-like 3 0.089
Cxcr7 chemokine (C-X-C motif) receptor 7 0.085
Egfr epidermal growth factor receptor 0.070
Ltf lactotransferrin 0.067
Slfn4 schlafen 4 0.063
Tpo thyroid peroxidase 0.059
Adam15 a disintegrin and metallopeptidase domain 15 (metargidin) 0.058
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.058
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.054
Gja1 gap junction protein, alpha 1 0.052
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.048
Clec4e C-type lectin domain family 4, member e 0.046
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.043
Ntf3 neurotrophin 3 0.042
Mmp9 matrix metallopeptidase 9 0.041
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.039
Il1b interleukin 1 beta 0.036
Acvrl1 activin A receptor, type II-like 1 0.035
Cd44 CD44 antigen 0.034
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.033
Il1r2 interleukin 1 receptor, type II 0.030
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.029
Ccl4 chemokine (C-C motif) ligand 4 0.029
Sos1 son of sevenless homolog 1 (Drosophila) 0.027
Ccr1 chemokine (C-C motif) receptor 1 0.026
Adam8 a disintegrin and metallopeptidase domain 8 0.024
Efna1 ephrin A1 0.024
Nfe2 nuclear factor, erythroid derived 2 0.024
Ifitm6 interferon induced transmembrane protein 6 0.024
Chi3l1 chitinase 3-like 1 0.023
1100001G20Rik RIKEN cDNA 1100001G20 gene 0.023
Cxcl5 chemokine (C-X-C motif) ligand 5 0.022
Lama5 laminin, alpha 5 0.022
Jup junction plakoglobin 0.022
Saa3 serum amyloid A 3 0.022
Cd38 CD38 antigen 0.022
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.020
Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 0.020
Ggta1 glycoprotein galactosyltransferase alpha 1, 3 0.020
Mcpt8 mast cell protease 8 0.019
Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 0.019
Eng endoglin 0.018
Il18rap interleukin 18 receptor accessory protein 0.018
Il1rn interleukin 1 receptor antagonist 0.018
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.017
Fpr2 formyl peptide receptor 2 0.017
Ciita class II transactivator 0.017
Pglyrp1 peptidoglycan recognition protein 1 0.017
Thbs1 thrombospondin 1 0.017
Sell selectin, lymphocyte 0.016
Pdcd1lg2 programmed cell death 1 ligand 2 0.016
Tnfaip2 tumor necrosis factor, alpha-induced protein 2 0.016
Slpi secretory leukocyte peptidase inhibitor 0.015
Gp5 glycoprotein 5 (platelet) 0.015
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.015
Idua iduronidase, alpha-L- 0.015
Cx3cr1 chemokine (C-X3-C) receptor 1 0.015
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.015
Hdc histidine decarboxylase 0.014
Vegfa vascular endothelial growth factor A 0.014
Trem1 triggering receptor expressed on myeloid cells 1 0.014
Asprv1 aspartic peptidase, retroviral-like 1 0.014
Glipr2 GLI pathogenesis-related 2 0.013
Gata4 GATA binding protein 4 0.013
Mcam melanoma cell adhesion molecule 0.013
Wt1 Wilms tumor 1 homolog 0.012
Acr acrosin prepropeptide 0.012
Ccr6 chemokine (C-C motif) receptor 6 0.012
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.012
Selp selectin, platelet 0.012
Ccr2 chemokine (C-C motif) receptor 2 0.012
Gpr97 G protein-coupled receptor 97 0.012
Hif1a hypoxia inducible factor 1, alpha subunit 0.012
Ccl3 chemokine (C-C motif) ligand 3 0.012
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.011
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.011
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.011
Allc allantoicase 0.011
Ccl17 chemokine (C-C motif) ligand 17 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
S100a9 S100 calcium binding protein A9 0.068
S100a8 S100 calcium binding protein A8 0.029
Anxa1 annexin A1 0.014
Il1b interleukin 1 beta 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism