Process View
The network for 'cardiac muscle cell myoblast differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.932 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.883 | |
| NOTCH1 | notch 1 | 0.787 | |
| JAG1 | jagged 1 | 0.765 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.608 | |
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.588 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.547 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.424 | |
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.383 | |
| ATXN1L | ataxin 1-like | 0.333 | |
| NOTCH3 | notch 3 | 0.265 | |
| XIAP | X-linked inhibitor of apoptosis | 0.149 | |
| MYOG | myogenin (myogenic factor 4) | 0.039 | |
| MYOD1 | myogenic differentiation 1 | 0.029 | |
| SMAD1 | SMAD family member 1 | 0.026 | |
| GATA4 | GATA binding protein 4 | 0.021 | |
| MKL2 | MKL/myocardin-like 2 | 0.021 | |
| NOTCH2 | notch 2 | 0.019 | |
| SNW1 | SNW domain containing 1 | 0.016 | |
| ATXN1 | ataxin 1 | 0.015 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.013 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Shh | sonic hedgehog | 0.999 | |
| Pax2 | paired box gene 2 | 0.998 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.998 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.989 | |
| Pax3 | paired box gene 3 | 0.988 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.975 | |
| Fgf8 | fibroblast growth factor 8 | 0.956 | |
| Jag1 | jagged 1 | 0.947 | |
| Foxg1 | forkhead box G1 | 0.942 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.935 | |
| Pax6 | paired box gene 6 | 0.932 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.926 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.911 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.907 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.907 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.891 | |
| Sox2 | SRY-box containing gene 2 | 0.871 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.814 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.788 | |
| Wt1 | Wilms tumor 1 homolog | 0.783 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.769 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.767 | |
| Foxc1 | forkhead box C1 | 0.738 | |
| Hoxa1 | homeobox A1 | 0.717 | |
| Nodal | nodal | 0.664 | |
| Bmp4 | bone morphogenetic protein 4 | 0.648 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.630 | |
| Tbx1 | T-box 1 | 0.624 | |
| Foxc2 | forkhead box C2 | 0.621 | |
| Bdnf | brain derived neurotrophic factor | 0.615 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.589 | |
| Sall4 | sal-like 4 (Drosophila) | 0.580 | |
| Gata4 | GATA binding protein 4 | 0.525 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.502 | |
| Nanog | Nanog homeobox | 0.484 | |
| Dll1 | delta-like 1 (Drosophila) | 0.417 | |
| Msx1 | homeobox, msh-like 1 | 0.415 | |
| Lhx1 | LIM homeobox protein 1 | 0.402 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.386 | |
| Lhx3 | LIM homeobox protein 3 | 0.365 | |
| En1 | engrailed 1 | 0.349 | |
| Gata3 | GATA binding protein 3 | 0.343 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.342 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.339 | |
| Fgf10 | fibroblast growth factor 10 | 0.326 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.295 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.278 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.262 | |
| Msx2 | homeobox, msh-like 2 | 0.260 | |
| Psen1 | presenilin 1 | 0.257 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.254 | |
| Dlx5 | distal-less homeobox 5 | 0.244 | |
| Lhx9 | LIM homeobox protein 9 | 0.228 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.226 | |
| Hoxa13 | homeobox A13 | 0.223 | |
| Dll4 | delta-like 4 (Drosophila) | 0.220 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.201 | |
| Tbx3 | T-box 3 | 0.196 | |
| Efnb2 | ephrin B2 | 0.185 | |
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.184 | |
| Gsc | goosecoid homeobox | 0.179 | |
| Rarg | retinoic acid receptor, gamma | 0.179 | |
| Fgf3 | fibroblast growth factor 3 | 0.170 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.160 | |
| Phox2b | paired-like homeobox 2b | 0.155 | |
| Sox11 | SRY-box containing gene 11 | 0.146 | |
| Gja5 | gap junction protein, alpha 5 | 0.133 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.129 | |
| Rxra | retinoid X receptor alpha | 0.125 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.113 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.111 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.108 | |
| Hoxa11 | homeobox A11 | 0.094 | |
| Gata6 | GATA binding protein 6 | 0.092 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.090 | |
| Sall1 | sal-like 1 (Drosophila) | 0.085 | |
| Osr1 | odd-skipped related 1 (Drosophila) | 0.079 | |
| Prrx1 | paired related homeobox 1 | 0.078 | |
| Nog | noggin | 0.077 | |
| Foxh1 | forkhead box H1 | 0.073 | |
| En2 | engrailed 2 | 0.071 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.067 | |
| Smo | smoothened homolog (Drosophila) | 0.066 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.061 | |
| Sox9 | SRY-box containing gene 9 | 0.060 | |
| Hoxd11 | homeobox D11 | 0.057 | |
| Hmx3 | H6 homeobox 3 | 0.056 | |
| Tbx5 | T-box 5 | 0.055 | |
| Htt | huntingtin | 0.055 | |
| Bnc1 | basonuclin 1 | 0.053 | |
| Sox3 | SRY-box containing gene 3 | 0.049 | |
| Nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.049 | |
| Dlx2 | distal-less homeobox 2 | 0.047 | |
| Dlx1 | distal-less homeobox 1 | 0.047 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.045 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.045 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.043 | |
| Neurog2 | neurogenin 2 | 0.042 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.042 |