The network for 'regulation of neutrophil chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of neutrophil chemotaxis

Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CCL5 chemokine (C-C motif) ligand 5 0.990
IL8 interleukin 8 0.983
CCL4 chemokine (C-C motif) ligand 4 0.969
CXCL9 chemokine (C-X-C motif) ligand 9 0.862
CCR7 chemokine (C-C motif) receptor 7 0.820
CCL2 chemokine (C-C motif) ligand 2 0.819
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.795
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.652
CCL19 chemokine (C-C motif) ligand 19 0.647
CCL8 chemokine (C-C motif) ligand 8 0.614
IL1B interleukin 1, beta 0.585
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.542
CCR4 chemokine (C-C motif) receptor 4 0.539
IFNG interferon, gamma 0.461
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.458
PLEK pleckstrin 0.445
CCL20 chemokine (C-C motif) ligand 20 0.430
CXCL2 chemokine (C-X-C motif) ligand 2 0.396
IL6 interleukin 6 (interferon, beta 2) 0.386
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.383
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.358
IL2RB interleukin 2 receptor, beta 0.337
CXCL3 chemokine (C-X-C motif) ligand 3 0.321
CCR1 chemokine (C-C motif) receptor 1 0.305
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.295
CCL7 chemokine (C-C motif) ligand 7 0.289
CCL3 chemokine (C-C motif) ligand 3 0.285
CCL22 chemokine (C-C motif) ligand 22 0.281
CCL13 chemokine (C-C motif) ligand 13 0.274
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.269
CXCL13 chemokine (C-X-C motif) ligand 13 0.266
CXCL10 chemokine (C-X-C motif) ligand 10 0.259
DPP4 dipeptidyl-peptidase 4 0.186
TNF tumor necrosis factor 0.185
NCF2 neutrophil cytosolic factor 2 0.169
JAM2 junctional adhesion molecule 2 0.155
PLAUR plasminogen activator, urokinase receptor 0.145
TLR2 toll-like receptor 2 0.132
RGS1 regulator of G-protein signaling 1 0.129
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.125
ICAM1 intercellular adhesion molecule 1 0.103
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.099
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.095
IL2RG interleukin 2 receptor, gamma 0.083
VCAM1 vascular cell adhesion molecule 1 0.082
IRF4 interferon regulatory factor 4 0.079
JAM3 junctional adhesion molecule 3 0.070
SELE selectin E 0.067
IL7R interleukin 7 receptor 0.064
SLAMF7 SLAM family member 7 0.062
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.062
IL10RA interleukin 10 receptor, alpha 0.061
BCL2A1 BCL2-related protein A1 0.061
CXCL5 chemokine (C-X-C motif) ligand 5 0.058
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.057
VCAN versican 0.057
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.057
CXCL11 chemokine (C-X-C motif) ligand 11 0.055
AQP9 aquaporin 9 0.051
MYD88 myeloid differentiation primary response gene (88) 0.050
PDZK1 PDZ domain containing 1 0.049
TLR4 toll-like receptor 4 0.048
SOCS3 suppressor of cytokine signaling 3 0.048
IRAK4 interleukin-1 receptor-associated kinase 4 0.044
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.043
CD93 CD93 molecule 0.043
CD40LG CD40 ligand 0.042
CD83 CD83 molecule 0.039
TREM1 triggering receptor expressed on myeloid cells 1 0.039
CLEC7A C-type lectin domain family 7, member A 0.038
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.038
IL1RN interleukin 1 receptor antagonist 0.038
IL1R2 interleukin 1 receptor, type II 0.038
CD48 CD48 molecule 0.035
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.034
IL18RAP interleukin 18 receptor accessory protein 0.033
GYPC glycophorin C (Gerbich blood group) 0.032
CCR6 chemokine (C-C motif) receptor 6 0.031
IL1R1 interleukin 1 receptor, type I 0.031
DPT dermatopontin 0.030
CCL11 chemokine (C-C motif) ligand 11 0.030
TGFB1 transforming growth factor, beta 1 0.029
HLA-DRA major histocompatibility complex, class II, DR alpha 0.028
CXCR5 chemokine (C-X-C motif) receptor 5 0.028
IL16 interleukin 16 (lymphocyte chemoattractant factor) 0.028
SOD2 superoxide dismutase 2, mitochondrial 0.028
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.028
IDE insulin-degrading enzyme 0.027
CD86 CD86 molecule 0.026
CXCR2 chemokine (C-X-C motif) receptor 2 0.025
CD163 CD163 molecule 0.024
CCR3 chemokine (C-C motif) receptor 3 0.024
CXCR3 chemokine (C-X-C motif) receptor 3 0.024
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.024
PLAU plasminogen activator, urokinase 0.023
IL10 interleukin 10 0.020
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.020
FPR1 formyl peptide receptor 1 0.020
INHBA inhibin, beta A 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
jam2a junctional adhesion molecule 2a 0.060
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.042
dld deltaD 0.040
si:dkey-261h17.1 si:dkey-261h17.1 0.038
col1a1b collagen, type I, alpha 1b 0.028
kdrl kinase insert domain receptor like 0.023
angptl7 angiopoietin-like 7 0.020
card9 caspase recruitment domain family, member 9 0.016
myod1 myogenic differentiation 1 0.016
twist1a twist1a 0.014
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.014
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.013
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.013
sulf1 sulfatase 1 0.013
si:dkey-236e20.2 si:dkey-236e20.2 0.012
vgll2b vestigial like 2b 0.012
scpep1 serine carboxypeptidase 1 0.012
spns2 spinster homolog 2 (Drosophila) 0.012
prickle1b prickle homolog 1 (Drosophila) b 0.011
plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.011
nod1 nucleotide-binding oligomerization domain containing 1 0.011
fbn2b fibrillin 2b 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.987
Cd44 CD44 antigen 0.967
Ccr1 chemokine (C-C motif) receptor 1 0.966
Selp selectin, platelet 0.962
Ccr2 chemokine (C-C motif) receptor 2 0.959
Il1b interleukin 1 beta 0.813
Ccl3 chemokine (C-C motif) ligand 3 0.788
Lyz2 lysozyme 2 0.729
Itgax integrin alpha X 0.716
Ccl8 chemokine (C-C motif) ligand 8 0.535
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.506
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.492
Cxcl13 chemokine (C-X-C motif) ligand 13 0.492
H2-Aa histocompatibility 2, class II antigen A, alpha 0.471
Ltb lymphotoxin B 0.451
C3ar1 complement component 3a receptor 1 0.437
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.436
Fcgr1 Fc receptor, IgG, high affinity I 0.434
Il2rb interleukin 2 receptor, beta chain 0.418
Itgb2 integrin beta 2 0.409
H2-Eb1 histocompatibility 2, class II antigen E beta 0.394
Icam1 intercellular adhesion molecule 1 0.306
Batf basic leucine zipper transcription factor, ATF-like 0.300
AF251705 cDNA sequence AF251705 0.299
Ctsw cathepsin W 0.296
Cxcr2 chemokine (C-X-C motif) receptor 2 0.291
Ccl7 chemokine (C-C motif) ligand 7 0.279
Il1r1 interleukin 1 receptor, type I 0.274
Ccl9 chemokine (C-C motif) ligand 9 0.244
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.243
Tnf tumor necrosis factor 0.240
Il10ra interleukin 10 receptor, alpha 0.232
Ccl12 chemokine (C-C motif) ligand 12 0.232
Sfpi1 SFFV proviral integration 1 0.217
Hp haptoglobin 0.214
Cx3cr1 chemokine (C-X3-C) receptor 1 0.205
Ccl4 chemokine (C-C motif) ligand 4 0.204
Gzma granzyme A 0.196
Chi3l3 chitinase 3-like 3 0.188
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.185
Ifng interferon gamma 0.181
Il1rn interleukin 1 receptor antagonist 0.180
Mmp8 matrix metallopeptidase 8 0.171
Mmp12 matrix metallopeptidase 12 0.168
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.164
Ccl6 chemokine (C-C motif) ligand 6 0.164
Cd7 CD7 antigen 0.162
Sele selectin, endothelial cell 0.157
Lin7c lin-7 homolog C (C. elegans) 0.157
Msr1 macrophage scavenger receptor 1 0.155
Cybb cytochrome b-245, beta polypeptide 0.149
Slfn1 schlafen 1 0.143
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.142
Folr2 folate receptor 2 (fetal) 0.141
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.138
Itgal integrin alpha L 0.138
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.137
Lta lymphotoxin A 0.121
Il1a interleukin 1 alpha 0.120
Cxcl2 chemokine (C-X-C motif) ligand 2 0.115
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.115
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.114
Bdkrb1 bradykinin receptor, beta 1 0.109
Cd3e CD3 antigen, epsilon polypeptide 0.109
Ifitm6 interferon induced transmembrane protein 6 0.102
Csf1 colony stimulating factor 1 (macrophage) 0.102
Mmp9 matrix metallopeptidase 9 0.099
Ciita class II transactivator 0.099
Ch25h cholesterol 25-hydroxylase 0.097
Ubd ubiquitin D 0.097
Cd14 CD14 antigen 0.097
Selplg selectin, platelet (p-selectin) ligand 0.096
Xcr1 chemokine (C motif) receptor 1 0.096
Casp1 caspase 1 0.095
Sh2d2a SH2 domain protein 2A 0.093
Myo1f myosin IF 0.091
Tlr4 toll-like receptor 4 0.091
Slit3 slit homolog 3 (Drosophila) 0.090
Gzmb granzyme B 0.085
Rac1 RAS-related C3 botulinum substrate 1 0.085
Stat5a signal transducer and activator of transcription 5A 0.084
Fpr3 formyl peptide receptor 3 0.083
Cd96 CD96 antigen 0.081
Gm14548 predicted gene 14548 0.081
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.080
C3 complement component 3 0.080
Cxcr3 chemokine (C-X-C motif) receptor 3 0.080
Fas Fas (TNF receptor superfamily member 6) 0.078
Tlr2 toll-like receptor 2 0.077
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.077
Robo1 roundabout homolog 1 (Drosophila) 0.076
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.071
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.071
Cxcl1 chemokine (C-X-C motif) ligand 1 0.071
Il18r1 interleukin 18 receptor 1 0.071
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.070
Cd2 CD2 antigen 0.069
Ly9 lymphocyte antigen 9 0.067
Ifngr1 interferon gamma receptor 1 0.065
Ccl5 chemokine (C-C motif) ligand 5 0.064
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Rattus norvegicus
Name Description Probability Func Analog Organism
Il2rg interleukin 2 receptor, gamma 0.230
Ccl3 chemokine (C-C motif) ligand 3 0.182
Ccl4 chemokine (C-C motif) ligand 4 0.180
Il1a interleukin 1 alpha 0.153
Il6 interleukin 6 0.101
Cxcl2 chemokine (C-X-C motif) ligand 2 0.100
Mefv Mediterranean fever 0.085
Csf3 colony stimulating factor 3 (granulocyte) 0.083
Cd83 CD83 molecule 0.079
Ccr5 chemokine (C-C motif) receptor 5 0.073
RT1-Da RT1 class II, locus Da 0.066
Ccr2 chemokine (C-C motif) receptor 2 0.064
Gzmk granzyme K 0.057
Il9r interleukin 9 receptor 0.056
Cd86 CD86 molecule 0.050
Ccr3 chemokine (C-C motif) receptor 3 0.049
Reg3g regenerating islet-derived 3 gamma 0.039
Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma 0.035
Selp selectin P 0.031
Olr1500 olfactory receptor 1500 0.030
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.028
Tcrb T-cell receptor beta chain 0.028
RT1-DMa RT1 class II, locus DMa 0.027
RT1-DMb RT1 class II, locus DMb 0.026
Ccl20 chemokine (C-C motif) ligand 20 0.025
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.024
Psp parotid secretory protein 0.023
Fcnb ficolin B 0.022
Zcwpw1 zinc finger, CW-type with PWWP domain 1 0.022
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.022
Gabre gamma-aminobutyric acid (GABA) A receptor, epsilon 0.021
Cd69 Cd69 molecule 0.021
Napsa napsin A aspartic peptidase 0.020
Cxcl10 chemokine (C-X-C motif) ligand 10 0.020
Cd4 Cd4 molecule 0.019
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.018
Hck hemopoietic cell kinase 0.018
Batf basic leucine zipper transcription factor, ATF-like 0.018
Fgf2 fibroblast growth factor 2 0.017
RT1-Ba RT1 class II, locus Ba 0.016
Rab20 RAB20, member RAS oncogene family 0.015
Ptprc protein tyrosine phosphatase, receptor type, C 0.014
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.013
Fam65b family with sequence similarity 65, member B 0.013
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.012
Arl5c ADP-ribosylation factor-like 5C 0.012
S1pr2 sphingosine-1-phosphate receptor 2 0.012
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.012
Tcf4 transcription factor 4 0.011
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.011
Dio2 deiodinase, iodothyronine, type II 0.011
Cdon Cdon homolog (mouse) 0.011
Lepr leptin receptor 0.011
Il1b interleukin 1 beta 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism