IMP
Process View
The network for 'negative regulation of lipopolysaccharide mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of lipopolysaccharide mediated signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.247 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.063 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.060 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.059 | |
| TNIP2 | TNFAIP3 interacting protein 2 | 0.057 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.055 | |
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.051 | |
| PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.047 | |
| TRAF6 | TNF receptor-associated factor 6 | 0.042 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.030 | |
| IER2 | immediate early response 2 | 0.025 | |
| SQSTM1 | sequestosome 1 | 0.025 | |
| ATF5 | activating transcription factor 5 | 0.023 | |
| SLMAP | sarcolemma associated protein | 0.020 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.014 | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.013 | |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.012 | |
| BAD | BCL2-associated agonist of cell death | 0.012 | |
| JUN | jun proto-oncogene | 0.012 | |
| HECTD1 | HECT domain containing 1 | 0.011 | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.010 | |
| CLEC18C | C-type lectin domain family 18, member C | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tnf | tumor necrosis factor | 0.332 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.268 | |
| Il1b | interleukin 1 beta | 0.207 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.175 | |
| Il1rn | interleukin 1 receptor antagonist | 0.132 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.132 | |
| Ifitm6 | interferon induced transmembrane protein 6 | 0.120 | |
| Il1r2 | interleukin 1 receptor, type II | 0.111 | |
| Ngp | neutrophilic granule protein | 0.111 | |
| Clec4e | C-type lectin domain family 4, member e | 0.104 | |
| Traf2 | TNF receptor-associated factor 2 | 0.102 | |
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.094 | |
| Slfn4 | schlafen 4 | 0.091 | |
| Tnip1 | TNFAIP3 interacting protein 1 | 0.087 | |
| Clec4d | C-type lectin domain family 4, member d | 0.082 | |
| S100a8 | S100 calcium binding protein A8 (calgranulin A) | 0.080 | |
| Rel | reticuloendotheliosis oncogene | 0.078 | |
| Fam96a | family with sequence similarity 96, member A | 0.077 | |
| Slpi | secretory leukocyte peptidase inhibitor | 0.077 | |
| Txn1 | thioredoxin 1 | 0.068 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.065 | |
| Traf6 | TNF receptor-associated factor 6 | 0.065 | |
| Mmp8 | matrix metallopeptidase 8 | 0.060 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.057 | |
| Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.055 | |
| Tmco1 | transmembrane and coiled-coil domains 1 | 0.054 | |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.052 | |
| Fpr2 | formyl peptide receptor 2 | 0.052 | |
| Asprv1 | aspartic peptidase, retroviral-like 1 | 0.043 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.042 | |
| Tmed10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.040 | |
| Camp | cathelicidin antimicrobial peptide | 0.039 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.038 | |
| Il6 | interleukin 6 | 0.038 | |
| Cd19 | CD19 antigen | 0.036 | |
| Cd40 | CD40 antigen | 0.036 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.036 | |
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.036 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.036 | |
| Mx2 | myxovirus (influenza virus) resistance 2 | 0.036 | |
| Pim1 | proviral integration site 1 | 0.035 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.035 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.034 | |
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.034 | |
| Chi3l1 | chitinase 3-like 1 | 0.034 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.033 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.032 | |
| Mxd1 | MAX dimerization protein 1 | 0.031 | |
| Chi3l3 | chitinase 3-like 3 | 0.031 | |
| Cd300lf | CD300 antigen like family member F | 0.030 | |
| Mmp9 | matrix metallopeptidase 9 | 0.028 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.027 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.027 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.027 | |
| Sfpi1 | SFFV proviral integration 1 | 0.027 | |
| Mefv | Mediterranean fever | 0.026 | |
| Plaur | plasminogen activator, urokinase receptor | 0.026 | |
| Dusp2 | dual specificity phosphatase 2 | 0.026 | |
| Selp | selectin, platelet | 0.026 | |
| Dbi | diazepam binding inhibitor | 0.026 | |
| Adam8 | a disintegrin and metallopeptidase domain 8 | 0.025 | |
| Slfn1 | schlafen 1 | 0.025 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.024 | |
| Tnfaip2 | tumor necrosis factor, alpha-induced protein 2 | 0.024 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.024 | |
| Saa3 | serum amyloid A 3 | 0.024 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.023 | |
| Cd177 | CD177 antigen | 0.023 | |
| Gcsh | glycine cleavage system protein H (aminomethyl carrier) | 0.023 | |
| Trem1 | triggering receptor expressed on myeloid cells 1 | 0.022 | |
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.022 | |
| Ccrl2 | chemokine (C-C motif) receptor-like 2 | 0.022 | |
| Itgal | integrin alpha L | 0.022 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.022 | |
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.021 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.021 | |
| Fpr1 | formyl peptide receptor 1 | 0.021 | |
| Ubd | ubiquitin D | 0.021 | |
| Niacr1 | niacin receptor 1 | 0.021 | |
| Atf3 | activating transcription factor 3 | 0.020 | |
| Fosl2 | fos-like antigen 2 | 0.020 | |
| Hbb-b1 | hemoglobin, beta adult major chain | 0.020 | |
| Ndufs1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1 | 0.020 | |
| Lcn2 | lipocalin 2 | 0.020 | |
| Aicda | activation-induced cytidine deaminase | 0.020 | |
| Il1a | interleukin 1 alpha | 0.020 | |
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.019 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.019 | |
| Hdc | histidine decarboxylase | 0.019 | |
| Cyb5 | cytochrome b-5 | 0.018 | |
| Cst7 | cystatin F (leukocystatin) | 0.018 | |
| Kif4 | kinesin family member 4 | 0.017 | |
| Slc7a11 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 | 0.017 | |
| Padi4 | peptidyl arginine deiminase, type IV | 0.017 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.016 | |
| Zfp36 | zinc finger protein 36 | 0.016 | |
| Sell | selectin, lymphocyte | 0.016 | |
| Il10 | interleukin 10 | 0.015 | |
| Suclg1 | succinate-CoA ligase, GDP-forming, alpha subunit | 0.015 | |
| 1100001G20Rik | RIKEN cDNA 1100001G20 gene | 0.015 |