The network for 'proton transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proton transport

The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Homo sapiens
Name Description Probability Func Analog Organism
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.838
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.785
COX5B cytochrome c oxidase subunit Vb 0.734
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.551
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 0.517
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.352
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.341
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.265
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.213
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.198
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.181
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.180
COX2 cytochrome c oxidase subunit II 0.164
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.162
COX1 cytochrome c oxidase subunit I 0.158
COX7B cytochrome c oxidase subunit VIIb 0.150
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.147
CYC1 cytochrome c-1 0.112
SETD8 SET domain containing (lysine methyltransferase) 8 0.106
COX5A cytochrome c oxidase subunit Va 0.103
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.103
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.100
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.100
NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 0.094
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.082
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 0.079
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.073
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.072
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.066
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 0.062
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.061
PARK7 Parkinson disease (autosomal recessive, early onset) 7 0.051
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.051
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.048
TBC1D10A TBC1 domain family, member 10A 0.045
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.041
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.038
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.036
ND2 MTND2 0.036
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.033
EPB42 erythrocyte membrane protein band 4.2 0.033
PRDX2 peroxiredoxin 2 0.033
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.029
SLC9A1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.029
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.027
MRPS15 mitochondrial ribosomal protein S15 0.027
CA4 carbonic anhydrase IV 0.027
ANXA7 annexin A7 0.024
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 0.023
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.023
YBX1 Y box binding protein 1 0.023
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.022
CLN3 ceroid-lipofuscinosis, neuronal 3 0.021
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.021
EZR ezrin 0.020
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.020
SOD1 superoxide dismutase 1, soluble 0.019
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.018
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.018
CHP2 calcineurin B homologous protein 2 0.017
UBE4A ubiquitination factor E4A (UFD2 homolog, yeast) 0.017
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.017
CCDC56 coiled-coil domain containing 56 0.016
COX6C cytochrome c oxidase subunit VIc 0.015
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.015
EIF3I eukaryotic translation initiation factor 3, subunit I 0.014
PSAP prosaposin 0.014
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.013
PDZK1 PDZ domain containing 1 0.013
DDT D-dopachrome tautomerase 0.013
RAI1 retinoic acid induced 1 0.012
ODC1 ornithine decarboxylase 1 0.012
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.012
ATP6 ATP synthase F0 subunit 6 0.012
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.012
SIGMAR1 sigma non-opioid intracellular receptor 1 0.012
C2orf18 chromosome 2 open reading frame 18 0.012
ANXA9 annexin A9 0.011
NAGK N-acetylglucosamine kinase 0.011
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.011
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.011
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.318
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.210
cox5ab cytochrome c oxidase subunit Vab 0.181
cox8a cytochrome c oxidase subunit 8a 0.171
ca15a carbonic anhydrase XV a 0.070
pah phenylalanine hydroxylase 0.063
osr2 odd-skipped related 2 (Drosophila) 0.062
actn2 actinin, alpha 2 0.053
sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.042
cox6a1 cytochrome c oxidase subunit VIa polypeptide 1 0.041
slc4a4a solute carrier family 4, member 4a 0.038
zgc:111961 zgc:111961 0.036
cx39.9 connexin 39.9 0.034
atp6v1g1 ATPase, H+ transporting, V1 subunit G isoform 1 0.034
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.027
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.026
fgf20b fibroblast growth factor 20b 0.026
zgc:73293 zgc:73293 0.024
ndfip1 Nedd4 family interacting protein 1 0.023
atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.022
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.022
pdzk1 PDZ domain containing 1 0.021
cdh17 cadherin 17, LI cadherin (liver-intestine) 0.020
slc25a3a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a 0.018
atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d 0.018
slc25a3b solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b 0.018
stra6 stimulated by retinoic acid gene 6 homolog (mouse) 0.017
cap2 CAP, adenylate cyclase-associated protein, 2 (yeast) 0.017
zgc:194876 zgc:194876 0.016
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.016
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.016
uqcrb ubiquinol-cytochrome c reductase binding protein 0.016
ndufs7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase) 0.015
slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.015
alx4a aristaless-like homeobox 4a 0.014
LOC100332034 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like 0.014
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.011
aco2 aconitase 2, mitochondrial 0.011
gja3 gap junction protein, alpha 3 0.011
slc4a2a solute carrier family 4, anion exchanger, member 2a 0.011
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.010
zgc:92631 zgc:92631 0.010
slc13a1 solute carrier family 13 (sodium/sulphate symporters), member 1 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Vha55 Vacuolar H[+]-ATPase 55kD B subunit 0.421
Vha26 Vacuolar H[+]-ATPase 26kD E subunit 0.119
VhaSFD Vacuolar H[+]-ATPase SFD subunit 0.074
a5 antennal protein 5 0.068
l(1)G0230 lethal (1) G0230 0.045
l(2)06225 lethal (2) 06225 0.036
ATPsyn-gamma ATP synthase-gamma chain 0.028
CG10664 CG10664 gene product from transcript CG10664-RB 0.028
mtt mangetout 0.022
VhaPPA1-1 CG7007 gene product from transcript CG7007-RA 0.021
AGO2 Argonaute 2 0.018
EfTuM Elongation factor Tu mitochondrial 0.018
Cyt-c-p Cytochrome c proximal 0.017
ATPsyn-b ATP synthase, subunit b 0.016
Hsc70-5 Heat shock protein cognate 5 0.015
Acon Aconitase 0.014
l(2)35Di lethal (2) 35Di 0.012
slif slimfast 0.012
Vps35 Vacuolar protein sorting 35 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.860
Neurod1 neurogenic differentiation 1 0.791
Kiss1 KiSS-1 metastasis-suppressor 0.599
Spna1 spectrin alpha 1 0.401
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.345
Pax6 paired box gene 6 0.329
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.311
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.305
Cox5b cytochrome c oxidase, subunit Vb 0.304
Aco2 aconitase 2, mitochondrial 0.246
Ptf1a pancreas specific transcription factor, 1a 0.223
Hbb-b1 hemoglobin, beta adult major chain 0.218
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.213
Hand2 heart and neural crest derivatives expressed transcript 2 0.207
Neurod4 neurogenic differentiation 4 0.187
Msx1 homeobox, msh-like 1 0.184
Umod uromodulin 0.183
Ank1 ankyrin 1, erythroid 0.167
Hand1 heart and neural crest derivatives expressed transcript 1 0.151
Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 0.143
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.142
Nhlh1 nescient helix loop helix 1 0.134
Dlx6 distal-less homeobox 6 0.131
Neurog2 neurogenin 2 0.118
Cyc1 cytochrome c-1 0.113
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.113
Atp6v0b ATPase, H+ transporting, lysosomal V0 subunit B 0.112
Gsc goosecoid homeobox 0.110
Vamp2 vesicle-associated membrane protein 2 0.102
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.099
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.096
Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.092
Pax9 paired box gene 9 0.087
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.086
Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 0.085
Evx1 even skipped homeotic gene 1 homolog 0.084
Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.083
Tbx1 T-box 1 0.075
Isl1 ISL1 transcription factor, LIM/homeodomain 0.075
Otx2 orthodenticle homolog 2 (Drosophila) 0.072
Kcnk3 potassium channel, subfamily K, member 3 0.071
Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C 0.071
Clstn1 calsyntenin 1 0.069
Neurog3 neurogenin 3 0.068
Foxi1 forkhead box I1 0.067
Prrx1 paired related homeobox 1 0.065
Mab21l2 mab-21-like 2 (C. elegans) 0.065
Cidec cell death-inducing DFFA-like effector c 0.064
Prph2 peripherin 2 0.064
Mecom MDS1 and EVI1 complex locus 0.061
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.060
Bspry B-box and SPRY domain containing 0.059
Pdzd3 PDZ domain containing 3 0.059
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.059
BC031181 cDNA sequence BC031181 0.056
Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 0.056
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.056
Sim2 single-minded homolog 2 (Drosophila) 0.055
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.055
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.054
Phb2 prohibitin 2 0.054
Prrx2 paired related homeobox 2 0.053
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.053
Fgf8 fibroblast growth factor 8 0.052
Cckbr cholecystokinin B receptor 0.052
Pdx1 pancreatic and duodenal homeobox 1 0.052
Mdh2 malate dehydrogenase 2, NAD (mitochondrial) 0.052
Epor erythropoietin receptor 0.051
Smo smoothened homolog (Drosophila) 0.048
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.047
Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.046
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.046
Cryga crystallin, gamma A 0.045
Prox1 prospero-related homeobox 1 0.044
Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 0.044
Osta organic solute transporter alpha 0.043
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.043
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.043
Hbb-b2 hemoglobin, beta adult minor chain 0.042
Etv2 ets variant gene 2 0.042
Fgf4 fibroblast growth factor 4 0.042
Asb9 ankyrin repeat and SOCS box-containing 9 0.042
Gata1 GATA binding protein 1 0.042
Tcfap2a transcription factor AP-2, alpha 0.041
Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H 0.041
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.039
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.039
Dlx2 distal-less homeobox 2 0.039
Lmx1b LIM homeobox transcription factor 1 beta 0.039
Atp6v1e1 ATPase, H+ transporting, lysosomal V1 subunit E1 0.039
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.039
Klf1 Kruppel-like factor 1 (erythroid) 0.038
Slc26a7 solute carrier family 26, member 7 0.038
Exoc6 exocyst complex component 6 0.038
Prr15 proline rich 15 0.037
Cs citrate synthase 0.037
Prph peripherin 0.037
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.036
Scnn1g sodium channel, nonvoltage-gated 1 gamma 0.035
Il9r interleukin 9 receptor 0.035
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ATP1 Atp1p 0.997
ATP4 Atp4p 0.995
ATP2 Atp2p 0.921
ATP5 Atp5p 0.872
ATP7 Atp7p 0.835
ENA5 Ena5p 0.785
ATP18 Atp18p 0.775
ATP20 Atp20p 0.740
PET9 Pet9p 0.634
VMA13 Vma13p 0.586
VMA1 Vma1p 0.541
ATP15 Atp15p 0.533
ENA2 Ena2p 0.520
ATP16 Atp16p 0.501
VMA5 Vma5p 0.492
ATP17 Atp17p 0.482
ATP3 Atp3p 0.464
ATP14 Atp14p 0.453
AFG3 Afg3p 0.300
NDE1 Nde1p 0.251
TIM11 Tim11p 0.171
ATP6 Atp6p 0.158
COX8 Cox8p 0.131
COX9 Cox9p 0.131
MDM38 Mdm38p 0.131
MIR1 Mir1p 0.098
INH1 Inh1p 0.095
IMD2 Imd2p 0.087
COX7 Cox7p 0.085
VMA4 Vma4p 0.080
SFB3 Sfb3p 0.078
USA1 Usa1p 0.071
COX4 Cox4p 0.068
TNA1 Tna1p 0.057
LCB2 Lcb2p 0.057
PEX2 Pex2p 0.055
MDM32 Mdm32p 0.049
YER064C hypothetical protein 0.048
ENA1 Ena1p 0.047
SPF1 Spf1p 0.045
PDC5 Pdc5p 0.044
RPM2 Rpm2p 0.043
HOR2 Hor2p 0.042
PMA1 Pma1p 0.040
GDH3 Gdh3p 0.040
ARR3 Arr3p 0.040
YLR264C-A hypothetical protein 0.039
SRD1 Srd1p 0.038
ATP8 Atp8p 0.038
YNL217W hypothetical protein 0.037
MLS1 Mls1p 0.037
ZPR1 Zpr1p 0.036
YHR033W hypothetical protein 0.035
QCR6 Qcr6p 0.035
COX13 Cox13p 0.035
YLR162W hypothetical protein 0.034
HXK2 Hxk2p 0.033
YCL057C-A hypothetical protein 0.033
KHA1 Kha1p 0.033
YJR120W hypothetical protein 0.032
YOL038C-A hypothetical protein 0.032
YHR078W hypothetical protein 0.032
GSC2 Gsc2p 0.032
COX2 Cox2p 0.031
ZPS1 Zps1p 0.031
ADH2 Adh2p 0.031
YJL107C hypothetical protein 0.030
MER1 Mer1p 0.030
LEU2 Leu2p 0.030
UPS3 Ups3p 0.030
OPT2 Opt2p 0.029
HPF1 Hpf1p 0.029
KNH1 Knh1p 0.028
OLI1 F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2 0.028
CUP1-1 Cup1-1p 0.028
ARP10 Arp10p 0.027
CWP1 Cwp1p 0.027
PDC6 Pdc6p 0.027
YOL014W hypothetical protein 0.027
BI4 Bi4p 0.026
YAR068W hypothetical protein 0.026
ICS2 Ics2p 0.026
NEO1 Neo1p 0.026
HXT3 Hxt3p 0.026
SGE1 Sge1p 0.026
SNG1 Sng1p 0.026
YEL073C hypothetical protein 0.025
BSC2 Bsc2p 0.025
ARO10 Aro10p 0.025
YBR013C hypothetical protein 0.025
CAM1 Cam1p 0.025
YDR387C hypothetical protein 0.025
FMT1 Fmt1p 0.025
LRO1 Lro1p 0.024
MRH1 Mrh1p 0.024
ALY1 Aly1p 0.024
SIM1 Sim1p 0.024
AUA1 Aua1p 0.024
QCR2 Qcr2p 0.023
AIM13 Aim13p 0.023