The network for 'regulation of acetylcholine secretion neurotransmission' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of acetylcholine secretion neurotransmission

Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.

Name Description Probability Func Analog Organism
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.999
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.991
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.982
Bsn bassoon 0.977
Thrb thyroid hormone receptor beta 0.974
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.793
Drd2 dopamine receptor D2 0.768
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.697
Grid2 glutamate receptor, ionotropic, delta 2 0.696
Rho rhodopsin 0.622
Ache acetylcholinesterase 0.607
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.594
Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3 0.577
Ryr1 ryanodine receptor 1, skeletal muscle 0.550
Rac1 RAS-related C3 botulinum substrate 1 0.545
Mybph myosin binding protein H 0.494
Lpar5 lysophosphatidic acid receptor 5 0.488
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.470
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.469
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.410
Nos1 nitric oxide synthase 1, neuronal 0.401
Pitx3 paired-like homeodomain transcription factor 3 0.340
Myog myogenin 0.334
Kcnk4 potassium channel, subfamily K, member 4 0.333
Rapsn receptor-associated protein of the synapse 0.326
Thra thyroid hormone receptor alpha 0.324
Gprin1 G protein-regulated inducer of neurite outgrowth 1 0.323
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.307
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.289
Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.288
Gzmm granzyme M (lymphocyte met-ase 1) 0.287
Psap prosaposin 0.282
Dnajb5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.268
Krtap5-1 keratin associated protein 5-1 0.253
Has1 hyaluronan synthase1 0.251
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.235
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.233
Isl2 insulin related protein 2 (islet 2) 0.233
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.226
Arhgap1 Rho GTPase activating protein 1 0.225
Actl6b actin-like 6B 0.195
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.187
Kif5a kinesin family member 5A 0.186
Chrna10 cholinergic receptor, nicotinic, alpha polypeptide 10 0.180
Dcx doublecortin 0.173
Vip vasoactive intestinal polypeptide 0.164
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.162
Cga glycoprotein hormones, alpha subunit 0.153
Scgn secretagogin, EF-hand calcium binding protein 0.150
Dynlt1b dynein light chain Tctex-type 1D 0.147
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.134
Aff2 AF4/FMR2 family, member 2 0.133
Cadm3 cell adhesion molecule 3 0.132
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.132
Chrnb3 cholinergic receptor, nicotinic, beta polypeptide 3 0.132
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.132
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.127
Chrnd cholinergic receptor, nicotinic, delta polypeptide 0.127
Apc2 adenomatosis polyposis coli 2 0.121
Atcay ataxia, cerebellar, Cayman type homolog (human) 0.120
Cldn26 claudin 26 0.118
Grid1 glutamate receptor, ionotropic, delta 1 0.111
Tshr thyroid stimulating hormone receptor 0.111
Sag retinal S-antigen 0.110
Cpne6 copine VI 0.110
Gng4 guanine nucleotide binding protein (G protein), gamma 4 0.110
Nxnl2 nucleoredoxin-like 2 0.109
Scn8a sodium channel, voltage-gated, type VIII, alpha 0.109
Ecel1 endothelin converting enzyme-like 1 0.107
Cdk5r2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.106
Ly6h lymphocyte antigen 6 complex, locus H 0.106
Cbl Casitas B-lineage lymphoma 0.105
Alk anaplastic lymphoma kinase 0.105
Cplx1 complexin 1 0.105
Rbp3 retinol binding protein 3, interstitial 0.104
Zic4 zinc finger protein of the cerebellum 4 0.104
Sorcs3 sortilin-related VPS10 domain containing receptor 3 0.104
Stk32b serine/threonine kinase 32B 0.102
Adam11 a disintegrin and metallopeptidase domain 11 0.102
Sult4a1 sulfotransferase family 4A, member 1 0.099
Srrm3 serine/arginine repetitive matrix 3 0.098
Dcc deleted in colorectal carcinoma 0.098
Smyd1 SET and MYND domain containing 1 0.098
Drd4 dopamine receptor D4 0.098
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.096
Tpo thyroid peroxidase 0.095
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.095
Olfr140 olfactory receptor 140 0.094
Ropn1 ropporin, rhophilin associated protein 1 0.094
Per3 period homolog 3 (Drosophila) 0.092
Kcnd3 potassium voltage-gated channel, Shal-related family, member 3 0.092
Rgs8 regulator of G-protein signaling 8 0.091
Neurod2 neurogenic differentiation 2 0.089
Gh growth hormone 0.089
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.089
Lcn8 lipocalin 8 0.089
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.087
Ebf3 early B-cell factor 3 0.085
Prph2 peripherin 2 0.085
Nell2 NEL-like 2 (chicken) 0.085
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
gar-2 Protein GAR-2 0.177
itr-1 Protein ITR-1 0.162
unc-10 Protein UNC-10 0.093
F32B5.7 Protein F32B5.7 0.085
ist-1 Protein IST-1 0.080
let-23 Protein LET-23 0.072
trp-1 Protein TRP-1 0.063
nrx-1 Protein NRX-1 0.060
pkg-1 Protein PKG-1 0.045
gar-3 Protein GAR-3 0.044
nmur-4 Protein NMUR-4 0.042
rgs-6 Protein RGS-6 0.040
unc-36 Protein UNC-36 0.038
odr-7 Protein ODR-7 0.029
F28E10.1 Protein F28E10.1 0.029
egl-30 Protein EGL-30 0.028
unc-38 Protein UNC-38 0.027
cal-4 Protein CAL-4 0.027
eat-4 Protein EAT-4 0.027
F54G2.1 Protein F54G2.1 0.026
grk-2 Protein GRK-2 0.023
stim-1 Protein STIM-1 0.023
egl-36 Protein EGL-36 0.023
eat-16 Protein EAT-16 0.018
unc-17 Protein UNC-17 0.018
H10E21.5 Protein H10E21.5 0.018
unc-77 Protein UNC-77 0.017
frm-3 Protein FRM-3 0.017
egl-15 Protein EGL-15 0.017
odr-1 Protein ODR-1 0.017
aat-5 Protein AAT-5 0.017
camt-1 Protein CAMT-1 0.017
glr-5 Protein GLR-5 0.017
plc-1 Protein PLC-1 0.016
CELE_Y53F4B.5 Protein Y53F4B.5 0.016
goa-1 Protein GOA-1 0.016
unc-105 Protein UNC-105 0.016
pdfr-1 Protein PDFR-1 0.015
acr-2 Protein ACR-2 0.015
gpb-1 Protein GPB-1 0.015
unc-53 Protein UNC-53 0.014
unc-54 Protein UNC-54 0.014
unc-47 Protein UNC-47 0.014
pde-1 Protein PDE-1 0.014
R03G8.3 Protein R03G8.3 0.014
tag-89 Protein TAG-89 0.014
F45E4.3 Protein F45E4.3 0.014
nlg-1 Protein NLG-1 0.014
CELE_Y43F8C.11 Protein Y43F8C.11 0.013
tmc-2 Protein TMC-2 0.012
egl-23 Protein EGL-23 0.012
pes-7 Protein PES-7 0.012
rig-6 Protein RIG-6 0.012
unc-13 Protein UNC-13 0.012
vab-9 Protein VAB-9 0.011
sol-1 Protein SOL-1 0.011
rpm-1 Protein RPM-1 0.011
CELE_M176.5 Protein M176.5 0.011
CELE_R13H7.2 Protein R13H7.2 0.011
cah-2 Protein CAH-2 0.011
stau-1 Protein STAU-1 0.011
acc-4 Protein ACC-4 0.010
rgef-1 Protein RGEF-1 0.010
CELE_K08E7.8 Protein K08E7.8 0.010
T14B1.1 Protein T14B1.1 0.010
ccb-1 Protein CCB-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.022
Hpcal4 hippocalcin-like 4 0.013
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.012
Adora1 adenosine A1 receptor 0.012
Fgfr2 fibroblast growth factor receptor 2 0.011
Nfasc neurofascin 0.011
Hand1 heart and neural crest derivatives expressed 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism