The network for 'regulation of high voltage gated calcium channel activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of high voltage gated calcium channel activity

Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.

Name Description Probability Func Analog Organism
Pax2 paired box gene 2 0.963
Fgf10 fibroblast growth factor 10 0.937
Pax3 paired box gene 3 0.777
Shc3 src homology 2 domain-containing transforming protein C3 0.621
Nkx2-1 NK2 homeobox 1 0.492
Tbx10 T-box 10 0.439
Eya1 eyes absent 1 homolog (Drosophila) 0.313
Twist2 twist homolog 2 (Drosophila) 0.290
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.289
Hoxd11 homeobox D11 0.284
Zfpm2 zinc finger protein, multitype 2 0.275
Tcf21 transcription factor 21 0.267
Gbx2 gastrulation brain homeobox 2 0.264
Fgfr2 fibroblast growth factor receptor 2 0.259
Hmx3 H6 homeobox 3 0.233
Fgf3 fibroblast growth factor 3 0.231
Adra1a adrenergic receptor, alpha 1a 0.230
Shh sonic hedgehog 0.217
Cux2 cut-like homeobox 2 0.206
Hoxa11 homeobox A11 0.194
Lmx1a LIM homeobox transcription factor 1 alpha 0.168
Gata3 GATA binding protein 3 0.162
Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 0.156
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.153
Syt7 synaptotagmin VII 0.149
Cntn4 contactin 4 0.147
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.141
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.141
Chd7 chromodomain helicase DNA binding protein 7 0.141
Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.137
Hoxa1 homeobox A1 0.135
Pou3f4 POU domain, class 3, transcription factor 4 0.123
Hoxd13 homeobox D13 0.122
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.116
Kcnk3 potassium channel, subfamily K, member 3 0.111
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.105
Fgf8 fibroblast growth factor 8 0.103
AI118078 expressed sequence AI118078 0.098
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.097
Nog noggin 0.091
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.090
Rasgrp1 RAS guanyl releasing protein 1 0.087
Htr1f 5-hydroxytryptamine (serotonin) receptor 1F 0.084
Wnt9b wingless-type MMTV integration site 9B 0.083
Inpp5j inositol polyphosphate 5-phosphatase J 0.080
Gli1 GLI-Kruppel family member GLI1 0.080
Sox2 SRY-box containing gene 2 0.080
Egfr epidermal growth factor receptor 0.075
Cckbr cholecystokinin B receptor 0.075
Gdf11 growth differentiation factor 11 0.075
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.075
Cnih2 cornichon homolog 2 (Drosophila) 0.072
Spry4 sprouty homolog 4 (Drosophila) 0.072
Prrx1 paired related homeobox 1 0.071
Pitx2 paired-like homeodomain transcription factor 2 0.071
Adrb1 adrenergic receptor, beta 1 0.071
Btbd17 BTB (POZ) domain containing 17 0.070
Gja3 gap junction protein, alpha 3 0.068
Tmsb4x thymosin, beta 4, X chromosome 0.068
Pax8 paired box gene 8 0.067
Fgfbp1 fibroblast growth factor binding protein 1 0.066
Mme membrane metallo endopeptidase 0.066
Oprd1 opioid receptor, delta 1 0.065
Pou3f3 POU domain, class 3, transcription factor 3 0.065
Krt34 keratin 34 0.064
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.064
Pitx1 paired-like homeodomain transcription factor 1 0.064
Ebf3 early B-cell factor 3 0.063
Casq2 calsequestrin 2 0.063
Phkg1 phosphorylase kinase gamma 1 0.062
Hoxa13 homeobox A13 0.061
Gabrd gamma-aminobutyric acid (GABA) A receptor, subunit delta 0.061
Gh growth hormone 0.060
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.059
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.059
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.058
Park2 Parkinson disease (autosomal recessive, juvenile) 2, parkin 0.057
Usp13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.057
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.055
Mmp17 matrix metallopeptidase 17 0.055
Rgs4 regulator of G-protein signaling 4 0.055
Rxrg retinoid X receptor gamma 0.054
Dmrt1 doublesex and mab-3 related transcription factor 1 0.054
Rarb retinoic acid receptor, beta 0.053
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.053
Bai1 brain-specific angiogenesis inhibitor 1 0.052
Gnao1 guanine nucleotide binding protein, alpha O 0.051
Sult4a1 sulfotransferase family 4A, member 1 0.049
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.048
Dmc1 DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) 0.048
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.048
Tbx3 T-box 3 0.048
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.047
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.047
Jag1 jagged 1 0.046
Homer1 homer homolog 1 (Drosophila) 0.046
Gli2 GLI-Kruppel family member GLI2 0.045
Fgf13 fibroblast growth factor 13 0.045
Dhh desert hedgehog 0.045
Gpr37 G protein-coupled receptor 37 0.045
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.086
TBCB tubulin folding cofactor B 0.059
CAPN2 calpain 2, (m/II) large subunit 0.032
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.013
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.012
CAPZB capping protein (actin filament) muscle Z-line, beta 0.012
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.010
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.476
Sub1 SUB1 homolog (S. cerevisiae) 0.316
Calm1 calmodulin 1 0.292
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.265
Calm2 calmodulin 2 0.235
Dynll1 dynein light chain LC8-type 1 0.198
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.166
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.125
Hsbp1 heat shock factor binding protein 1 0.058
Tuba1c tubulin, alpha 1C 0.042
Tsc22d1 TSC22 domain family, member 1 0.029
Prnp prion protein 0.027
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.024
Ap2s1 adaptor-related protein complex 2, sigma 1 subunit 0.022
Tspan3 tetraspanin 3 0.017
Pfkm phosphofructokinase, muscle 0.016
Mrfap1 Mof4 family associated protein 1 0.016
Snurf SNRPN upstream reading frame 0.016
Ak1 adenylate kinase 1 0.016
Cltc clathrin, heavy chain (Hc) 0.015
Ubb ubiquitin B 0.013
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.013
COX2 COXII 0.013
Fkbp1a FK506 binding protein 1a 0.013
Cpe carboxypeptidase E 0.012
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.012
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.012
Nptn neuroplastin 0.011
Rab3a RAB3A, member RAS oncogene family 0.011
Prkaca protein kinase, cAMP-dependent, catalytic, alpha 0.011
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism