The network for 'response to unfolded protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to unfolded protein

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.

Danio rerio
Name Description Probability Func Analog Organism
manf mesencephalic astrocyte-derived neurotrophic factor 0.918
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.793
hspd1 heat shock 60kD protein 1 (chaperonin) 0.693
dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.581
dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.506
hyou1 hypoxia up-regulated 1 0.448
vmp1 vacuole membrane protein 1 0.255
calr calreticulin and calreticulin 0.250
pdia3 protein disulfide isomerase family A, member 3 0.248
hspa5 heat shock protein 5 0.226
pdia4 protein disulfide isomerase associated 4 0.182
calrl calreticulin like 0.169
hspa9 heat shock protein 9 0.165
mbnl2 muscleblind-like 2 (Drosophila) 0.148
hdlbp high density lipoprotein-binding protein (vigilin) 0.134
ccng1 cyclin G1 0.110
ldb3a LIM-domain binding factor 3a 0.110
canx calnexin 0.101
ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 0.085
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.082
hsp90a.2 heat shock protein 90-alpha 2 0.082
mylz3 myosin, light polypeptide 3, skeletal muscle 0.077
hspa4a heat shock protein 4a 0.075
pdip5 protein disulfide isomerase-related protein (provisional) 0.073
nucb2b nucleobindin 2b 0.066
copg2 coatomer protein complex, subunit gamma 2 0.066
zgc:153260 zgc:153260 0.065
syvn1 synovial apoptosis inhibitor 1, synoviolin 0.063
ddost dolichyl-diphosphooligosaccharide-protein glycosyltransferase 0.062
tmed2 transmembrane emp24 domain trafficking protein 2 0.062
mtdha metadherin a 0.060
txnrd1 thioredoxin reductase 1 0.059
pvalb2 parvalbumin 2 0.058
zgc:162630 zgc:162630 0.058
herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.057
tmed9 transmembrane emp24 protein transport domain containing 9 0.056
arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.053
srpr signal recognition particle receptor (docking protein) 0.053
prkcsh protein kinase C substrate 80K-H 0.052
zgc:73136 zgc:73136 0.052
irf11 interferon regulatory factor 11 0.052
yars tyrosyl-tRNA synthetase 0.052
nfe2l2 nuclear factor (erythroid-derived 2)-like 2 0.051
hspe1 heat shock 10 protein 1 (chaperonin 10) 0.051
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.051
pygmb phosphorylase, glycogen (muscle) b 0.051
jun jun proto-oncogene 0.050
adra2da adrenergic, alpha-2D-, receptor a 0.050
papss2b 3'-phosphoadenosine 5'-phosphosulfate synthase 2b 0.050
scamp2 secretory carrier membrane protein 2 0.050
slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.050
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.049
mxa myxovirus (influenza) resistance A 0.049
vmhc ventricular myosin heavy chain 0.049
calrl2 calreticulin, like 2 0.048
tbx5a T-box 5a 0.048
odc1 ornithine decarboxylase 1 0.047
mapkapk2a mitogen-activated protein kinase-activated protein kinase 2a 0.047
zgc:152873 zgc:152873 0.046
prpf8 pre-mRNA processing factor 8 0.046
pi4k2a phosphatidylinositol 4-kinase type 2 alpha 0.044
tufm Tu translation elongation factor, mitochondrial 0.044
zgc:165344 zgc:165344 0.043
lonp1 lon peptidase 1, mitochondrial 0.043
ctage5 CTAGE family, member 5 0.042
copb1 coatomer protein complex, subunit beta 1 0.042
pyya peptide YYa 0.042
arf2 ADP-ribosylation factor 2 0.040
midn midnolin 0.039
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.039
lars leucyl-tRNA synthetase 0.039
zgc:56419 zgc:56419 0.039
idh3a isocitrate dehydrogenase 3 (NAD+) alpha 0.038
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.038
pvalb4 parvalbumin 4 0.038
LOC566020 Gig2-like protein DreO 0.038
abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 0.037
ucp3 uncoupling protein 3 0.037
lonp2 lon peptidase 2, peroxisomal 0.037
mstnb myostatin b 0.037
nras neuroblastoma RAS viral (v-ras) oncogene homolog 0.036
pvalb7 parvalbumin 7 0.036
c20orf24 c20orf24 homolog (H. sapiens) 0.036
tram1 translocating chain-associating membrane protein 1 0.036
jak1 Janus kinase 1 0.036
btg1 B-cell translocation gene 1 0.035
nars asparaginyl-tRNA synthetase 0.035
vipr2 vasoactive intestinal peptide receptor 2 0.035
tnni2a.4 troponin I, skeletal, fast 2a.4 0.035
opn1mw2 opsin 1 (cone pigments), medium-wave-sensitive, 2 0.034
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.034
rab11a RAB11a, member RAS oncogene family 0.034
zgc:152896 zgc:152896 0.034
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.033
prelid1 PRELI domain containing 1 0.033
ncs1b neuronal calcium sensor 1b 0.033
b2m beta-2-microglobulin 0.033
zgc:77744 zgc:77744 0.033
zgc:64098 zgc:64098 0.032
sec61al2 Sec61 alpha like 2 0.032
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
abu-15 Protein ABU-15 0.996
abu-11 Protein ABU-11 0.994
hsp-16.41 Protein HSP-16.41 0.978
hsp-16.1 Protein HSP-16.1 0.977
abu-8 Protein ABU-8 0.971
abu-1 Protein ABU-1 0.963
tag-320 Protein TAG-320 0.957
abu-6 Protein ABU-6 0.930
hsp-70 Protein HSP-70 0.925
hsp-16.2 Protein HSP-16.2 0.902
dnj-7 Protein DNJ-7 0.824
F44E5.4 Protein F44E5.4 0.764
hsp-3 Protein HSP-3 0.707
Y47D3B.6 Protein Y47D3B.6 0.698
pqn-54 Protein PQN-54 0.637
hsp-16.48 Protein HSP-16.48 0.602
abu-10 Protein ABU-10 0.600
abu-9 Protein ABU-9 0.524
CELE_T05E11.3 Protein T05E11.3 0.477
pdi-2 Protein PDI-2 0.472
CELE_T06E4.9 Protein T06E4.9 0.468
sec-22 Protein SEC-22 0.463
abu-14 Protein ABU-14 0.455
pqn-74 Protein PQN-74 0.407
dct-18 Protein DCT-18 0.376
CELE_F20G2.2 Protein F20G2.2 0.359
CELE_F19B2.5 Protein F19B2.5 0.343
CELE_T06E4.8 Protein T06E4.8 0.327
pqn-63 Protein PQN-63 0.310
hsp-4 Protein HSP-4 0.309
Y94H6A.7 Protein Y94H6A.7 0.283
ckb-2 Protein CKB-2 0.276
F13E6.5 Protein F13E6.5 0.273
T08B1.1 Protein T08B1.1 0.247
F41E6.11 Protein F41E6.11 0.245
dsc-4 Protein DSC-4 0.242
pdi-3 Protein PDI-3 0.227
R02F11.1 Protein R02F11.1 0.224
ifd-1 Protein IFD-1 0.212
dnc-2 Protein DNC-2 0.211
lys-1 Protein LYS-1 0.207
hsp-1 Protein HSP-1 0.197
vha-17 Protein VHA-17 0.187
K02G10.1 Protein K02G10.1 0.181
stt-3 Protein STT-3 0.173
crt-1 Protein CRT-1 0.169
pqn-71 Protein PQN-71 0.166
R03C1.1 Protein R03C1.1 0.158
acs-4 Protein ACS-4 0.146
nhr-17 Protein NHR-17 0.143
sgt-1 Protein SGT-1 0.141
nipi-3 Protein NIPI-3 0.127
F22H10.3 Protein F22H10.3 0.125
dop-3 Protein DOP-3 0.125
tsr-1 Protein TSR-1 0.124
lbp-6 Protein LBP-6 0.120
Y51H7C.13 Protein Y51H7C.13 0.118
nspb-12 Protein NSPB-12 0.117
C01A2.4 Protein C01A2.4 0.115
Y76B12C.3 Protein Y76B12C.3 0.113
trap-2 Protein TRAP-2 0.113
pssy-1 Protein PSSY-1 0.111
paa-1 Protein PAA-1 0.111
apa-2 Protein APA-2 0.108
ppk-1 Protein PPK-1 0.106
rsbp-1 Protein RSBP-1 0.105
lron-2 Protein LRON-2 0.105
cnp-3 Protein CNP-3 0.104
ser-3 Protein SER-3 0.102
pqn-76 Protein PQN-76 0.102
tufm-1 Protein TUFM-1 0.102
CELE_Y39B6A.1 Protein Y39B6A.1 0.101
CELE_Y41C4A.11 Protein Y41C4A.11 0.100
haly-1 Protein HALY-1 0.098
hsp-17 Protein HSP-17 0.094
tars-1 Protein TARS-1 0.091
glod-4 Protein GLOD-4 0.087
dnj-13 Protein DNJ-13 0.086
mtp-18 Protein MTP-18 0.086
F54E2.1 Protein F54E2.1 0.086
F49E10.4 Protein F49E10.4 0.085
hsp-16.11 Protein HSP-16.11 0.084
lec-6 Protein LEC-6 0.078
gst-23 Protein GST-23 0.077
imp-2 Protein IMP-2 0.076
wdr-23 Protein WDR-23 0.075
mdt-28 Protein MDT-28 0.073
T25F10.3 Protein T25F10.3 0.072
unc-52 Protein UNC-52 0.071
F08H9.4 Protein F08H9.4 0.070
T14G8.3 Protein T14G8.3 0.070
Y5H2A.4 Protein Y5H2A.4 0.070
CELE_F52B11.2 Protein F52B11.2 0.069
scav-1 Protein SCAV-1 0.068
gst-1 Protein GST-1 0.067
coq-8 Protein COQ-8 0.066
grl-7 Protein GRL-7 0.066
somi-1 Protein SOMI-1 0.066
mec-8 Protein MEC-8 0.066
T21B6.3 Protein T21B6.3 0.065
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
CG7830 CG7830 gene product from transcript CG7830-RA 0.570
Acsl Acyl-CoA synthetase long-chain 0.371
Herp Homocysteine-induced endoplasmic reticulum protein 0.163
Spp Signal peptide protease 0.095
Rel Relish 0.092
CG3061 CG3061 gene product from transcript CG3061-RA 0.090
CG7371 CG7371 gene product from transcript CG7371-RA 0.077
scny scrawny 0.076
CG3781 CG3781 gene product from transcript CG3781-RA 0.061
Manf Mesencephalic astrocyte-derived neurotrophic factor 0.048
cwo clockwork orange 0.046
Vha55 Vacuolar H[+]-ATPase 55kD B subunit 0.046
CaBP1 CG5809 gene product from transcript CG5809-RA 0.044
CG9318 CG9318 gene product from transcript CG9318-RA 0.042
P58IPK CG8286 gene product from transcript CG8286-RA 0.042
Arr2 Arrestin 2 0.039
imd immune deficiency 0.039
myoglianin CG1838 gene product from transcript CG1838-RD 0.036
Pdi Protein disulfide isomerase 0.035
Der-2 Derlin-2 0.035
ERp60 CG8983 gene product from transcript CG8983-RA 0.033
milt milton 0.033
Spase25 Spase 25-subunit 0.031
Pak PAK-kinase 0.030
Hsc70-5 Heat shock protein cognate 5 0.030
Ark Apaf-1-related-killer 0.029
CG5484 CG5484 gene product from transcript CG5484-RC 0.028
Ero1L Endoplasmic reticulum oxidoreductin-1-like 0.028
ird5 immune response deficient 5 0.028
KdelR KDEL receptor 0.027
BG4 CG12297 gene product from transcript CG12297-RA 0.025
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.024
chp chaoptic 0.024
CG6191 CG6191 gene product from transcript CG6191-RA 0.023
Syx17 Syntaxin 17 0.022
CG4957 CG4957 gene product from transcript CG4957-RA 0.022
CG1418 CG1418 gene product from transcript CG1418-RA 0.022
Traf4 TNF-receptor-associated factor 4 0.022
Surf4 Surfeit 4 0.022
TRAM CG11642 gene product from transcript CG11642-RB 0.020
Gp93 Glycoprotein 93 0.018
flower CG6151 gene product from transcript CG6151-RA 0.017
Der-1 Derlin-1 0.017
CG6490 CG6490 gene product from transcript CG6490-RB 0.016
MESR6 Misexpression suppressor of ras 6 0.015
RagA CG11968 gene product from transcript CG11968-RA 0.014
CG9801 CG9801 gene product from transcript CG9801-RC 0.013
CG18619 CG18619 gene product from transcript CG18619-RD 0.013
Vhl von Hippel-Lindau 0.013
Lsd-2 Lipid storage droplet-2 0.013
CG5727 CG5727 gene product from transcript CG5727-RA 0.013
trbd trabid 0.012
CG9706 CG9706 gene product from transcript CG9706-RA 0.012
Coq2 Coenzyme Q biosynthesis protein 2 0.012
dmt dalmatian 0.011
CG1486 CG1486 gene product from transcript CG1486-RA 0.011
Smox Smad on X 0.011
sec63 CG8583 gene product from transcript CG8583-RA 0.011
CYLD cylindromatosis 0.011
Npc1b Niemann-Pick type C-1b 0.011
Sec22 CG7359 gene product from transcript CG7359-RA 0.011
slik Sterile20-like kinase 0.011
CG6259 CG6259 gene product from transcript CG6259-RA 0.011
Trxr-1 Thioredoxin reductase-1 0.011
desat1 CG5887 gene product from transcript CG5887-RA 0.011
CG15423 CG15423 gene product from transcript CG15423-RA 0.010
mnb minibrain 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.000
PDIA3 protein disulfide isomerase family A, member 3 1.000
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.000
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.999
HSPA8 heat shock 70kDa protein 8 0.994
VCP valosin containing protein 0.992
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.988
HSPA1B heat shock 70kDa protein 1B 0.984
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.973
PDIA4 protein disulfide isomerase family A, member 4 0.961
PDIA6 protein disulfide isomerase family A, member 6 0.957
CANX calnexin 0.954
BCL2L1 BCL2-like 1 0.933
HSPA1A heat shock 70kDa protein 1A 0.918
HSPH1 heat shock 105kDa/110kDa protein 1 0.867
GHR growth hormone receptor 0.768
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.751
DERL1 Der1-like domain family, member 1 0.723
BCL2 B-cell CLL/lymphoma 2 0.687
BAG3 BCL2-associated athanogene 3 0.658
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.650
HYOU1 hypoxia up-regulated 1 0.644
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.629
RPN1 ribophorin I 0.580
STON2 stonin 2 0.578
SELS selenoprotein S 0.572
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.558
BAX BCL2-associated X protein 0.534
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.469
P4HB prolyl 4-hydroxylase, beta polypeptide 0.449
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.437
MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) 0.397
FKBP4 FK506 binding protein 4, 59kDa 0.353
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.341
BAG1 BCL2-associated athanogene 0.325
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.245
BAG2 BCL2-associated athanogene 2 0.224
RPN2 ribophorin II 0.218
C19orf10 chromosome 19 open reading frame 10 0.218
C4orf14 chromosome 4 open reading frame 14 0.212
HSPB1 heat shock 27kDa protein 1 0.185
GANAB glucosidase, alpha; neutral AB 0.177
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.163
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.149
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.144
WDR83 WD repeat domain 83 0.143
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.132
CCND3 cyclin D3 0.131
MANF mesencephalic astrocyte-derived neurotrophic factor 0.131
ATF3 activating transcription factor 3 0.124
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.112
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.106
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.096
STIP1 stress-induced-phosphoprotein 1 0.095
BAK1 BCL2-antagonist/killer 1 0.093
JUN jun proto-oncogene 0.092
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.089
UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) 0.085
ATXN3 ataxin 3 0.082
AMFR autocrine motility factor receptor 0.076
BAD BCL2-associated agonist of cell death 0.076
USP46 ubiquitin specific peptidase 46 0.073
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.069
ATF2 activating transcription factor 2 0.067
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.067
COPG coatomer protein complex, subunit gamma 0.065
IER2 immediate early response 2 0.061
VDAC1 voltage-dependent anion channel 1 0.061
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.058
SSR1 signal sequence receptor, alpha 0.056
PPP5C protein phosphatase 5, catalytic subunit 0.055
TP53 tumor protein p53 0.054
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.052
RB1 retinoblastoma 1 0.050
NUCB2 nucleobindin 2 0.048
RNF144B ring finger protein 144B 0.045
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.044
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.043
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.041
DERL2 Der1-like domain family, member 2 0.041
GRB10 growth factor receptor-bound protein 10 0.040
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.037
SART1 squamous cell carcinoma antigen recognized by T cells 0.034
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.033
ERN1 endoplasmic reticulum to nucleus signaling 1 0.033
RNR2 l-rRNA 0.033
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase 0.031
OSBPL9 oxysterol binding protein-like 9 0.030
HM13 histocompatibility (minor) 13 0.029
KEAP1 kelch-like ECH-associated protein 1 0.029
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.029
TMED2 transmembrane emp24 domain trafficking protein 2 0.029
PPID peptidylprolyl isomerase D 0.028
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.028
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.028
UBE4B ubiquitination factor E4B (UFD2 homolog, yeast) 0.028
SEC62 SEC62 homolog (S. cerevisiae) 0.027
UBXN2A UBX domain protein 2A 0.026
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.026
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.026
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Hspa5 heat shock protein 5 0.996
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.994
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.867
Manf mesencephalic astrocyte-derived neurotrophic factor 0.784
Pdia3 protein disulfide isomerase associated 3 0.770
Cdk4 cyclin-dependent kinase 4 0.759
Cdk6 cyclin-dependent kinase 6 0.665
Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.663
Creld2 cysteine-rich with EGF-like domains 2 0.541
Sdf2l1 stromal cell-derived factor 2-like 1 0.507
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.469
Canx calnexin 0.454
Xbp1 X-box binding protein 1 0.378
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.332
Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 0.331
Edem1 ER degradation enhancer, mannosidase alpha-like 1 0.286
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.281
Pdia6 protein disulfide isomerase associated 6 0.252
Tram1 translocating chain-associating membrane protein 1 0.212
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.203
Magt1 magnesium transporter 1 0.200
H47 histocompatibility 47 0.199
Surf4 surfeit gene 4 0.184
Ngly1 N-glycanase 1 0.184
Slc39a7 solute carrier family 39 (zinc transporter), member 7 0.182
Mgat2 mannoside acetylglucosaminyltransferase 2 0.177
Serp1 stress-associated endoplasmic reticulum protein 1 0.165
Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.156
Tmed7 transmembrane emp24 protein transport domain containing 7 0.156
Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.152
Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 0.151
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.144
Slc30a5 solute carrier family 30 (zinc transporter), member 5 0.144
Lman1 lectin, mannose-binding, 1 0.126
Ssr1 signal sequence receptor, alpha 0.118
Vcp valosin containing protein 0.097
Atf6 activating transcription factor 6 0.093
Ccnd1 cyclin D1 0.086
Prkcsh protein kinase C substrate 80K-H 0.083
Il18 interleukin 18 0.077
Erp44 endoplasmic reticulum protein 44 0.075
Atf4 activating transcription factor 4 0.068
Hspd1 heat shock protein 1 (chaperonin) 0.068
Slc35b1 solute carrier family 35, member B1 0.068
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 0.066
Gbp5 guanylate binding protein 5 0.066
Tlr4 toll-like receptor 4 0.063
Tm9sf3 transmembrane 9 superfamily member 3 0.061
Rpn2 ribophorin II 0.061
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.059
Calr calreticulin 0.058
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.057
Sars seryl-aminoacyl-tRNA synthetase 0.057
Fndc3a fibronectin type III domain containing 3A 0.055
Rpn1 ribophorin I 0.055
Pdia4 protein disulfide isomerase associated 4 0.052
Tmem33 transmembrane protein 33 0.050
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.048
Rrbp1 ribosome binding protein 1 0.047
Dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.046
Slc31a1 solute carrier family 31, member 1 0.043
Il1b interleukin 1 beta 0.043
Mcfd2 multiple coagulation factor deficiency 2 0.042
Hspa9 heat shock protein 9 0.041
Bak1 BCL2-antagonist/killer 1 0.039
Rnf103 ring finger protein 103 0.039
Sec23b SEC23B (S. cerevisiae) 0.037
Hsph1 heat shock 105kDa/110kDa protein 1 0.036
P4hb prolyl 4-hydroxylase, beta polypeptide 0.035
Gbp7 guanylate binding protein 7 0.035
Txndc5 thioredoxin domain containing 5 0.035
Ssr3 signal sequence receptor, gamma 0.034
Hif1a hypoxia inducible factor 1, alpha subunit 0.034
Tmed2 transmembrane emp24 domain trafficking protein 2 0.034
Hspa8 heat shock protein 8 0.033
Tm9sf2 transmembrane 9 superfamily member 2 0.032
Uba5 ubiquitin-like modifier activating enzyme 5 0.032
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.031
Arhgap31 Rho GTPase activating protein 31 0.030
Lass2 LAG1 homolog, ceramide synthase 2 0.029
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.026
Rpe ribulose-5-phosphate-3-epimerase 0.026
Syvn1 synovial apoptosis inhibitor 1, synoviolin 0.026
Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.025
Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) 0.025
Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.025
Nars asparaginyl-tRNA synthetase 0.025
Hspa13 heat shock protein 70 family, member 13 0.024
Tars threonyl-tRNA synthetase 0.023
Hyou1 hypoxia up-regulated 1 0.023
Nmi N-myc (and STAT) interactor 0.023
Derl2 Der1-like domain family, member 2 0.023
Lonp1 lon peptidase 1, mitochondrial 0.022
Yars tyrosyl-tRNA synthetase 0.022
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.021
Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 0.021
Map3k2 mitogen-activated protein kinase kinase kinase 2 0.021
Gmppb GDP-mannose pyrophosphorylase B 0.021
Cdk2 cyclin-dependent kinase 2 0.021
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.021
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hsph1 heat shock 105/110 protein 1 0.839
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.524
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.397
Hspd1 heat shock protein 1 (chaperonin) 0.294
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.210
Hspa8 heat shock protein 8 0.199
Stip1 stress-induced phosphoprotein 1 0.104
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.049
Hspa5 heat shock protein 5 0.042
LOC681996 similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 1 0.031
Pdia6 protein disulfide isomerase family A, member 6 0.019
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.016
Canx calnexin 0.013
Hsp90b1 heat shock protein 90, beta, member 1 0.012
Hspb1 heat shock protein 1 0.012
Lamp2 lysosomal-associated membrane protein 2 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
PMT1 Pmt1p 0.340
PMT2 Pmt2p 0.151
KSS1 Kss1p 0.150
MSG5 Msg5p 0.134
SSA3 Ssa3p 0.102
PMT3 Pmt3p 0.071
ERO1 Ero1p 0.070
RLM1 Rlm1p 0.067
RIM21 Rim21p 0.066
SSA4 Ssa4p 0.066
HRD3 Hrd3p 0.062
SPF1 Spf1p 0.055
SIS1 Sis1p 0.051
STI1 Sti1p 0.051
ALD6 Ald6p 0.049
DFM1 Dfm1p 0.049
KRE1 Kre1p 0.048
YHB1 Yhb1p 0.043
SFB3 Sfb3p 0.043
DER1 Der1p 0.042
PMT5 Pmt5p 0.042
GLO3 Glo3p 0.039
CAB3 Cab3p 0.039
SSA1 Ssa1p 0.037
SIL1 Sil1p 0.036
USA1 Usa1p 0.035
PDI1 Pdi1p 0.035
SSA2 Ssa2p 0.035
HAC1 Hac1p 0.033
AHA1 Aha1p 0.033
YDJ1 Ydj1p 0.032
VHS3 Vhs3p 0.032
KAR2 Kar2p 0.032
YIP4 Yip4p 0.031
BST1 Bst1p 0.030
CTR9 Ctr9p 0.029
TRA1 Tra1p 0.029
GID8 Gid8p 0.029
VMA13 Vma13p 0.028
PDR12 Pdr12p 0.027
JEM1 Jem1p 0.027
PMA1 Pma1p 0.027
BFR1 Bfr1p 0.026
CRP1 Crp1p 0.026
KTR1 Ktr1p 0.025
MCD4 Mcd4p 0.025
OYE2 Oye2p 0.025
PCL9 Pcl9p 0.025
HDA2 Hda2p 0.024
HEM13 Hem13p 0.024
BIG1 Big1p 0.024
SCS2 Scs2p 0.024
RSN1 Rsn1p 0.023
HSP60 Hsp60p 0.023
YPL088W hypothetical protein 0.023
MDL1 Mdl1p 0.023
IRA1 Ira1p 0.023
BTN2 Btn2p 0.022
FUS3 Fus3p 0.022
SOK2 Sok2p 0.022
YHR162W hypothetical protein 0.022
SGT2 Sgt2p 0.022
KRE6 Kre6p 0.022
KNH1 Knh1p 0.022
INO2 Ino2p 0.022
PMT6 Pmt6p 0.022
PCL5 Pcl5p 0.021
MGR1 Mgr1p 0.021
PBS2 Pbs2p 0.021
UFD2 Ufd2p 0.021
BUL2 Bul2p 0.021
TSC3 Tsc3p 0.020
BCK2 Bck2p 0.020
PDR5 Pdr5p 0.020
SRD1 Srd1p 0.020
KSP1 Ksp1p 0.020
ALG12 Alg12p 0.019
MPD1 Mpd1p 0.019
ADA2 Ada2p 0.019
SSK1 Ssk1p 0.019
YLR264C-A hypothetical protein 0.019
YLR162W hypothetical protein 0.019
MDH2 Mdh2p 0.019
YML6 Yml6p 0.019
RGD2 Rgd2p 0.018
ARG8 Arg8p 0.018
CWH43 Cwh43p 0.018
CUP1-1 Cup1-1p 0.018
HMG2 Hmg2p 0.018
LEU2 Leu2p 0.018
RAD34 Rad34p 0.018
LHS1 Lhs1p 0.018
URA3 Ura3p 0.018
CWH41 Cwh41p 0.018
RHO1 Rho1p 0.018
EMP24 Emp24p 0.018
ATG13 Atg13p 0.018
CNE1 Cne1p 0.018
YOL038C-A hypothetical protein 0.017
BET2 Bet2p 0.017