IMP

Process View

Homo sapiens

7 genes annotated in human

Multi-species View

negative regulation of interleukin 2 production

GO:0032703

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 2 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of interleukin 2 production" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.815
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.444
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.322
CXCL2	chemokine (C-X-C motif) ligand 2	0.266
WDR5	WD repeat domain 5	0.230
CXCL9	chemokine (C-X-C motif) ligand 9	0.192
AR	androgen receptor	0.100
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.090
KAT5	K(lysine) acetyltransferase 5	0.076
TRIM21	tripartite motif containing 21	0.074	Human
CCL2	chemokine (C-C motif) ligand 2	0.070	Human
CCL8	chemokine (C-C motif) ligand 8	0.063	Human
PML	promyelocytic leukemia	0.061
MED15	mediator complex subunit 15	0.058
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.055	Human
CCR7	chemokine (C-C motif) receptor 7	0.053
CXCL10	chemokine (C-X-C motif) ligand 10	0.052
RGS1	regulator of G-protein signaling 1	0.049
SLMAP	sarcolemma associated protein	0.048
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.047
TRIM5	tripartite motif containing 5	0.045	Human
CCL13	chemokine (C-C motif) ligand 13	0.041	Human
DPP4	dipeptidyl-peptidase 4	0.039
CCL5	chemokine (C-C motif) ligand 5	0.035	Human
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.033
ZNF263	zinc finger protein 263	0.033
TNF	tumor necrosis factor	0.031
PRKD2	protein kinase D2	0.029
CDK11B	cyclin-dependent kinase 11B	0.028
HDAC4	histone deacetylase 4	0.026	Human
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.026
CXCL11	chemokine (C-X-C motif) ligand 11	0.026
TRIM39	tripartite motif containing 39	0.025	Human
IL8	interleukin 8	0.023
PLK3	polo-like kinase 3	0.022
PPARA	peroxisome proliferator-activated receptor alpha	0.022
IFI16	interferon, gamma-inducible protein 16	0.022
IFNG	interferon, gamma	0.021
IL6	interleukin 6 (interferon, beta 2)	0.018
MAGEA2	melanoma antigen family A, 2	0.018
CCR4	chemokine (C-C motif) receptor 4	0.018
RNF11	ring finger protein 11	0.017
EEF1G	eukaryotic translation elongation factor 1 gamma	0.017
IL1B	interleukin 1, beta	0.017
ARIH2	ariadne homolog 2 (Drosophila)	0.016
FPR3	formyl peptide receptor 3	0.016
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.016
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.016
CCL19	chemokine (C-C motif) ligand 19	0.014	Human
IDE	insulin-degrading enzyme	0.014
ZNF473	zinc finger protein 473	0.013
CXCL13	chemokine (C-X-C motif) ligand 13	0.013
HDAC7	histone deacetylase 7	0.013
CCL4	chemokine (C-C motif) ligand 4	0.013	Human
ATM	ataxia telangiectasia mutated	0.013
TRIM17	tripartite motif containing 17	0.012	Human
UBD	ubiquitin D	0.012
KIAA1377	KIAA1377	0.012
CCL22	chemokine (C-C motif) ligand 22	0.011	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.011
IL7R	interleukin 7 receptor	0.011
NCOR1	nuclear receptor corepressor 1	0.011
IL2RB	interleukin 2 receptor, beta	0.011
TRIM26	tripartite motif containing 26	0.010
FHL1	four and a half LIM domains 1	0.010