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Process View

Homo sapiens

22 genes annotated in human

hormone biosynthetic process

The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hormone biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hormone biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.928	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.893
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.807	Human
EPAS1	endothelial PAS domain protein 1	0.726	Human
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.687	Rat
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.665	Fly
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.524	Fly
ESR1	estrogen receptor 1	0.456
GH1	growth hormone 1	0.427	Rat
EGFR	epidermal growth factor receptor	0.364
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.317
CSH2	chorionic somatomammotropin hormone 2	0.243	Rat
CREBBP	CREB binding protein	0.210
EGLN1	egl nine homolog 1 (C. elegans)	0.208
GH2	growth hormone 2	0.202	Rat
ITGB1BP3	integrin beta 1 binding protein 3	0.198
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.189
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.183
AHR	aryl hydrocarbon receptor	0.164
BMPR1B	bone morphogenetic protein receptor, type IB	0.151
CSHL1	chorionic somatomammotropin hormone-like 1	0.135	Rat
EGLN3	egl nine homolog 3 (C. elegans)	0.128
CLOCK	clock homolog (mouse)	0.104
VHL	von Hippel-Lindau tumor suppressor	0.103
PDCD6IP	programmed cell death 6 interacting protein	0.088
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.062
GRB10	growth factor receptor-bound protein 10	0.054
SOS1	son of sevenless homolog 1 (Drosophila)	0.050
SH3GL3	SH3-domain GRB2-like 3	0.050
CD2	CD2 molecule	0.050
SH3KBP1	SH3-domain kinase binding protein 1	0.046
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.045
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.042
SH3GL2	SH3-domain GRB2-like 2	0.038
FAF1	Fas (TNFRSF6) associated factor 1	0.038
NCOA1	nuclear receptor coactivator 1	0.037
ARNT	aryl hydrocarbon receptor nuclear translocator	0.035
FGF18	fibroblast growth factor 18	0.034
AR	androgen receptor	0.032
MTA3	metastasis associated 1 family, member 3	0.031
IGF2R	insulin-like growth factor 2 receptor	0.031
MAPK15	mitogen-activated protein kinase 15	0.030
TUBB2B	tubulin, beta 2B	0.028
FGF4	fibroblast growth factor 4	0.027
WNT4	wingless-type MMTV integration site family, member 4	0.027
BLNK	B-cell linker	0.027
MYO6	myosin VI	0.026
CAT	catalase	0.025
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.024
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.024
ZFYVE9	zinc finger, FYVE domain containing 9	0.023
FGF8	fibroblast growth factor 8 (androgen-induced)	0.023
PGRMC1	progesterone receptor membrane component 1	0.023
NCOA2	nuclear receptor coactivator 2	0.022
SPRY2	sprouty homolog 2 (Drosophila)	0.022
CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	0.022
NCOA3	nuclear receptor coactivator 3	0.021
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.021
SSX4	synovial sarcoma, X breakpoint 4	0.021
IRS1	insulin receptor substrate 1	0.021
CD2AP	CD2-associated protein	0.021
COL2A1	collagen, type II, alpha 1	0.019
KAT2B	K(lysine) acetyltransferase 2B	0.019
WIF1	WNT inhibitory factor 1	0.019
SMAD9	SMAD family member 9	0.019
MED13	mediator complex subunit 13	0.019
SMAD3	SMAD family member 3	0.018
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.018
NRP1	neuropilin 1	0.018
RCOR1	REST corepressor 1	0.018
DLX4	distal-less homeobox 4	0.017
TG	thyroglobulin	0.017
LPHN1	latrophilin 1	0.017
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.017
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.016	Human
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.016
NIPSNAP3A	nipsnap homolog 3A (C. elegans)	0.016
PRKCQ	protein kinase C, theta	0.016
SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	0.015
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.015
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.015
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.015
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.015
CARHSP1	calcium regulated heat stable protein 1, 24kDa	0.015
FZD10	frizzled homolog 10 (Drosophila)	0.015
LTBP4	latent transforming growth factor beta binding protein 4	0.015
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.015
HOXD9	homeobox D9	0.014
FOXD3	forkhead box D3	0.014
FSTL1	follistatin-like 1	0.014
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.014
SOX21	SRY (sex determining region Y)-box 21	0.014
PTH1R	parathyroid hormone 1 receptor	0.014
MMP25	matrix metallopeptidase 25	0.014
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.013
CALCA	calcitonin-related polypeptide alpha	0.013
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.013
ANXA4	annexin A4	0.013
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.013
WNT1	wingless-type MMTV integration site family, member 1	0.013	Human
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.013
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.013
SP1	Sp1 transcription factor	0.012
CREB1	cAMP responsive element binding protein 1	0.012
IHH	Indian hedgehog	0.012
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.012
SFRP1	secreted frizzled-related protein 1	0.012
TRAF4	TNF receptor-associated factor 4	0.012
EFNB3	ephrin-B3	0.012
RET	ret proto-oncogene	0.012
CSK	c-src tyrosine kinase	0.012
DUSP9	dual specificity phosphatase 9	0.012
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.012
SNAI1	snail homolog 1 (Drosophila)	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
POU2F1	POU class 2 homeobox 1	0.011
PTHLH	parathyroid hormone-like hormone	0.011
RXRA	retinoid X receptor, alpha	0.011
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.011
TGOLN2	trans-golgi network protein 2	0.011
NPAS2	neuronal PAS domain protein 2	0.011
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.011
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.011
PRMT6	protein arginine methyltransferase 6	0.011
COL4A6	collagen, type IV, alpha 6	0.011
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.011
JPH3	junctophilin 3	0.011
BNC1	basonuclin 1	0.011
ZMYND11	zinc finger, MYND-type containing 11	0.011
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.010
BZRAP1	benzodiazapine receptor (peripheral) associated protein 1	0.010
FOXF2	forkhead box F2	0.010
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.010
ARTN	artemin	0.010
PAX7	paired box 7	0.010
UTF1	undifferentiated embryonic cell transcription factor 1	0.010
RARA	retinoic acid receptor, alpha	0.010
PAX2	paired box 2	0.010
B2M	beta-2-microglobulin	0.010
BMP8A	bone morphogenetic protein 8a	0.010	Human
MEGF6	multiple EGF-like-domains 6	0.010
VEGFC	vascular endothelial growth factor C	0.010
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.010