IMP

Process View

Homo sapiens

3 genes annotated in human

skeletal myofibril assembly

The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal myofibril assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "skeletal myofibril assembly" (in gray)

Name	Description	Probability	Func Analog Organism
ACTB	actin, beta	0.855	Human
ACTG1	actin, gamma 1	0.840	Human
TRIM63	tripartite motif containing 63	0.784
CFL1	cofilin 1 (non-muscle)	0.698
ARHGAP1	Rho GTPase activating protein 1	0.599
NEB	nebulin	0.542
MYOZ1	myozenin 1	0.517
ANK1	ankyrin 1, erythrocytic	0.325
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.244
TNNC1	troponin C type 1 (slow)	0.200
RHOA	ras homolog gene family, member A	0.189	Worm
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.188
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.171
MYH9	myosin, heavy chain 9, non-muscle	0.154
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.145
HDAC4	histone deacetylase 4	0.145
TUBA1B	tubulin, alpha 1b	0.095
MYH11	myosin, heavy chain 11, smooth muscle	0.087
HNF4A	hepatocyte nuclear factor 4, alpha	0.084
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.083
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.080
CNN2	calponin 2	0.077
ACTN1	actinin, alpha 1	0.076
CAPN3	calpain 3, (p94)	0.072
CFL2	cofilin 2 (muscle)	0.071
FAS	Fas (TNF receptor superfamily, member 6)	0.066
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.056
TAGLN2	transgelin 2	0.049
ACTA1	actin, alpha 1, skeletal muscle	0.047
HDAC9	histone deacetylase 9	0.045
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.045
ZYX	zyxin	0.044
TPM4	tropomyosin 4	0.036
SUGT1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	0.035
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.035
CACYBP	calcyclin binding protein	0.033
OBSL1	obscurin-like 1	0.031
FLNA	filamin A, alpha	0.029
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.026
TPM1	tropomyosin 1 (alpha)	0.026
ACTA2	actin, alpha 2, smooth muscle, aorta	0.025	Human
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.024
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.023
ACTC1	actin, alpha, cardiac muscle 1	0.023	Human
TNNI2	troponin I type 2 (skeletal, fast)	0.022
MSN	moesin	0.022
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.021
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.021
GSN	gelsolin	0.021
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.020
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.020
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.019
RHOC	ras homolog gene family, member C	0.019	Worm
ACTN2	actinin, alpha 2	0.019
PFN1	profilin 1	0.019
SPTBN1	spectrin, beta, non-erythrocytic 1	0.019
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.019
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.018
MEF2A	myocyte enhancer factor 2A	0.018
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.017
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.017
SREBF2	sterol regulatory element binding transcription factor 2	0.016
DES	desmin	0.016
VASP	vasodilator-stimulated phosphoprotein	0.016
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.015
MYOZ2	myozenin 2	0.015
HSPH1	heat shock 105kDa/110kDa protein 1	0.015
MYLK2	myosin light chain kinase 2	0.015
CKM	creatine kinase, muscle	0.015
CAPNS1	calpain, small subunit 1	0.015
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.015
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.015
ENO3	enolase 3 (beta, muscle)	0.015
PKM2	pyruvate kinase, muscle	0.014
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.014
OSTF1	osteoclast stimulating factor 1	0.014
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.014
LDB3	LIM domain binding 3	0.014
EZR	ezrin	0.014
EPAS1	endothelial PAS domain protein 1	0.014
CSRP1	cysteine and glycine-rich protein 1	0.013
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.013
TNNC2	troponin C type 2 (fast)	0.013
WDR1	WD repeat domain 1	0.013	Worm
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.013
DSTN	destrin (actin depolymerizing factor)	0.013
PDLIM7	PDZ and LIM domain 7 (enigma)	0.013
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.013
MRPL41	mitochondrial ribosomal protein L41	0.012
TNNT3	troponin T type 3 (skeletal, fast)	0.012
MYBPC2	myosin binding protein C, fast type	0.012
ACTN4	actinin, alpha 4	0.012
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.012
ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.012
SPTB	spectrin, beta, erythrocytic	0.012
MYBPH	myosin binding protein H	0.011
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.011
TMSB10	thymosin beta 10	0.011
FBXO25	F-box protein 25	0.011
EHD4	EH-domain containing 4	0.011
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.011
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.011
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.011
ACTG2	actin, gamma 2, smooth muscle, enteric	0.011	Human
CTBP2	C-terminal binding protein 2	0.011
OAZ1	ornithine decarboxylase antizyme 1	0.010
REPS2	RALBP1 associated Eps domain containing 2	0.010
TNNI3	troponin I type 3 (cardiac)	0.010
TK1	thymidine kinase 1, soluble	0.010
SYNPO2L	synaptopodin 2-like	0.010
JUP	junction plakoglobin	0.010
CNN1	calponin 1, basic, smooth muscle	0.010
MYL9	myosin, light chain 9, regulatory	0.010