IMP

Process View

Homo sapiens

14 genes annotated in human

ventricular cardiac muscle tissue development

The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventricular cardiac muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventricular cardiac muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
TNNC1	troponin C type 1 (slow)	0.995
TNNI1	troponin I type 1 (skeletal, slow)	0.991	Human Mouse
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.974
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.940
TPM1	tropomyosin 1 (alpha)	0.896
DSP	desmoplakin	0.717	Mouse
TBX5	T-box 5	0.685	Mouse
MYH9	myosin, heavy chain 9, non-muscle	0.678
TNNI2	troponin I type 2 (skeletal, fast)	0.678	Human
TNNT2	troponin T type 2 (cardiac)	0.646
TPM2	tropomyosin 2 (beta)	0.631	Human
SMYD1	SET and MYND domain containing 1	0.616
CKM	creatine kinase, muscle	0.543
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.477
TNNT3	troponin T type 3 (skeletal, fast)	0.454	Human
FGF1	fibroblast growth factor 1 (acidic)	0.423
ACVR1B	activin A receptor, type IB	0.389
TAL1	T-cell acute lymphocytic leukemia 1	0.376	Human
NOTCH1	notch 1	0.367	Mouse
SFN	stratifin	0.359
ACTA1	actin, alpha 1, skeletal muscle	0.328
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.326
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.287
TRIM63	tripartite motif containing 63	0.286
LDB3	LIM domain binding 3	0.278
JUP	junction plakoglobin	0.275
GATA4	GATA binding protein 4	0.274	Zebrafish Mouse
JAG1	jagged 1	0.268
SETD8	SET domain containing (lysine methyltransferase) 8	0.214
FGF10	fibroblast growth factor 10	0.209
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.206
MYBPC2	myosin binding protein C, fast type	0.190
KRT14	keratin 14	0.182
HNF4A	hepatocyte nuclear factor 4, alpha	0.178
HAP1	huntingtin-associated protein 1	0.164
PSEN1	presenilin 1	0.147
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.145
RARA	retinoic acid receptor, alpha	0.141
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.129	Human
SMAD3	SMAD family member 3	0.116
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.114	Human
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.114	Human
TNNT1	troponin T type 1 (skeletal, slow)	0.112	Human
PDLIM7	PDZ and LIM domain 7 (enigma)	0.104
PKP2	plakophilin 2	0.102
TNNC2	troponin C type 2 (fast)	0.098	Human
FLNA	filamin A, alpha	0.097
KRT18	keratin 18	0.085
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.083	Human
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.079
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.078
GSK3B	glycogen synthase kinase 3 beta	0.074
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.074
NOTCH3	notch 3	0.072
KRT8	keratin 8	0.064
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.064	Human
ACTN1	actinin, alpha 1	0.061
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.059	Mouse
MYBPC1	myosin binding protein C, slow type	0.054
MYOD1	myogenic differentiation 1	0.054
SMAD9	SMAD family member 9	0.053
CXXC5	CXXC finger protein 5	0.053
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.051
DES	desmin	0.051
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.050	Human
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.050
MAML1	mastermind-like 1 (Drosophila)	0.049
ACTN3	actinin, alpha 3	0.047
PDX1	pancreatic and duodenal homeobox 1	0.041
TGFBR1	transforming growth factor, beta receptor 1	0.041
MARK3	MAP/microtubule affinity-regulating kinase 3	0.040
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.040
MED25	mediator complex subunit 25	0.039
GATA2	GATA binding protein 2	0.038
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.036	Human
MYBPH	myosin binding protein H	0.035
CTBP2	C-terminal binding protein 2	0.034
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.033
CORO1C	coronin, actin binding protein, 1C	0.030
ACTB	actin, beta	0.030
TPM4	tropomyosin 4	0.029	Human
ANK1	ankyrin 1, erythrocytic	0.028
SOX7	SRY (sex determining region Y)-box 7	0.028
SMAD6	SMAD family member 6	0.027
SLN	sarcolipin	0.027
ACTC1	actin, alpha, cardiac muscle 1	0.026
TNNI3	troponin I type 3 (cardiac)	0.026
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.025
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.025
CDK19	cyclin-dependent kinase 19	0.024
PGAM2	phosphoglycerate mutase 2 (muscle)	0.024
RBBP4	retinoblastoma binding protein 4	0.023
MB	myoglobin	0.021
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.021
FGF7	fibroblast growth factor 7	0.020
SKIL	SKI-like oncogene	0.020
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.019
MYH4	myosin, heavy chain 4, skeletal muscle	0.019	Human
CASQ2	calsequestrin 2 (cardiac muscle)	0.019
TGFB1	transforming growth factor, beta 1	0.019
FRMD5	FERM domain containing 5	0.018
FLNB	filamin B, beta	0.018
SMPX	small muscle protein, X-linked	0.018
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.017
CAV3	caveolin 3	0.017
TCAP	titin-cap (telethonin)	0.016
PHOX2A	paired-like homeobox 2a	0.016
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.016
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.016
ATXN1L	ataxin 1-like	0.016
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.016
LAD1	ladinin 1	0.016
TTN	titin	0.016
ACTN2	actinin, alpha 2	0.015
HTT	huntingtin	0.015
MYOZ1	myozenin 1	0.014
TNNI3K	TNNI3 interacting kinase	0.014
RIPK3	receptor-interacting serine-threonine kinase 3	0.014
CALD1	caldesmon 1	0.014
MYLK	myosin light chain kinase	0.014
DSC2	desmocollin 2	0.014
PKP4	plakophilin 4	0.013	Human
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.013	Human
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.013
MYL7	myosin, light chain 7, regulatory	0.013	Human
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.012
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.012
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.012
DSG2	desmoglein 2	0.012
MYOG	myogenin (myogenic factor 4)	0.012
VCP	valosin containing protein	0.012
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.012
PRKD2	protein kinase D2	0.012
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.012
MED10	mediator complex subunit 10	0.011
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.011
AKAP6	A kinase (PRKA) anchor protein 6	0.011
CNN2	calponin 2	0.011
PKD2L1	polycystic kidney disease 2-like 1	0.011
DSG1	desmoglein 1	0.011
TAGLN	transgelin	0.011
RPL3L	ribosomal protein L3-like	0.010
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.010
SIX6	SIX homeobox 6	0.010
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.010