IMP
Process View
Homo sapiens
13 genes annotated in human
lower respiratory tract disease
DOID:0050161
A respiratory system disease which involves the lower respiratory tract.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "lower respiratory tract disease"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.999 | ||
| PDZK1 | PDZ domain containing 1 | 0.998 | ||
| GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.990 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.989 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.953 | ||
| SCNN1B | sodium channel, nonvoltage-gated 1, beta | 0.948 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.937 | ||
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.837 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.723 | ||
| CLCN3 | chloride channel 3 | 0.600 | ||
| BCR | breakpoint cluster region | 0.557 | ||
| PTEN | phosphatase and tensin homolog | 0.361 | ||
| LRRC50 | leucine rich repeat containing 50 | 0.243 | ||
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.229 | ||
| DMBT1 | deleted in malignant brain tumors 1 | 0.222 | ||
| SCNN1A | sodium channel, nonvoltage-gated 1 alpha | 0.199 | ||
| SFTPD | surfactant protein D | 0.159 | Human | |
| SFTPB | surfactant protein B | 0.136 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.134 | ||
| EPN1 | epsin 1 | 0.101 | ||
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.071 | ||
| SFTPC | surfactant protein C | 0.069 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.067 | ||
| SCNN1G | sodium channel, nonvoltage-gated 1, gamma | 0.066 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.065 | ||
| MUC13 | mucin 13, cell surface associated | 0.059 | ||
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.055 | ||
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.053 | ||
| EZR | ezrin | 0.053 | ||
| TJP3 | tight junction protein 3 (zona occludens 3) | 0.051 | ||
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.050 | ||
| CANX | calnexin | 0.049 | ||
| SFTPA2 | surfactant protein A2 | 0.047 | ||
| CD33 | CD33 molecule | 0.046 | ||
| EPOR | erythropoietin receptor | 0.045 | ||
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.037 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.037 | ||
| ARRDC3 | arrestin domain containing 3 | 0.032 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.031 | ||
| RYR2 | ryanodine receptor 2 (cardiac) | 0.029 | ||
| RNF5 | ring finger protein 5 | 0.028 | ||
| EPCAM | epithelial cell adhesion molecule | 0.027 | ||
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.026 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.025 | ||
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | 0.023 | ||
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.023 | ||
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.022 | ||
| MUC4 | mucin 4, cell surface associated | 0.022 | ||
| MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 | 0.022 | ||
| JAK2 | Janus kinase 2 | 0.021 | ||
| CLCA1 | chloride channel accessory 1 | 0.021 | ||
| DNAI2 | dynein, axonemal, intermediate chain 2 | 0.020 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.019 | ||
| SPDEF | SAM pointed domain containing ets transcription factor | 0.018 | ||
| SLC26A3 | solute carrier family 26, member 3 | 0.018 | ||
| PIGR | polymeric immunoglobulin receptor | 0.017 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.016 | ||
| CLEC4A | C-type lectin domain family 4, member A | 0.016 | ||
| ADCY8 | adenylate cyclase 8 (brain) | 0.016 | ||
| ROS1 | c-ros oncogene 1 , receptor tyrosine kinase | 0.016 | ||
| LPAR2 | lysophosphatidic acid receptor 2 | 0.016 | ||
| SMAD1 | SMAD family member 1 | 0.015 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.013 | ||
| CLEC7A | C-type lectin domain family 7, member A | 0.013 | ||
| HIGD1B | HIG1 hypoxia inducible domain family, member 1B | 0.013 | ||
| HNF1B | HNF1 homeobox B | 0.013 | ||
| C20orf114 | chromosome 20 open reading frame 114 | 0.013 | ||
| NKX2-1 | NK2 homeobox 1 | 0.012 | ||
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.012 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.012 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.012 | ||
| STX1A | syntaxin 1A (brain) | 0.012 | ||
| PLEK | pleckstrin | 0.012 | ||
| FAM83E | family with sequence similarity 83, member E | 0.011 | ||
| CLDN18 | claudin 18 | 0.011 | ||
| TFF3 | trefoil factor 3 (intestinal) | 0.011 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.011 | ||
| VIM | vimentin | 0.010 | ||
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.010 | ||
| SLC34A2 | solute carrier family 34 (sodium phosphate), member 2 | 0.005 | ||
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.004 | ||
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.002 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.002 | ||
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.001 | ||
| SFTPA1 | surfactant protein A1 | 0.001 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.001 |