IMP
Process View
collagen catabolic process
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "collagen catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.950 | ||
| CD63 | CD63 molecule | 0.931 | ||
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.851 | ||
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.666 | ||
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.394 | Mouse | |
| FLNB | filamin B, beta | 0.356 | ||
| CYTH1 | cytohesin 1 | 0.336 | ||
| FHL2 | four and a half LIM domains 2 | 0.322 | ||
| NPC2 | Niemann-Pick disease, type C2 | 0.255 | ||
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.181 | ||
| PSAP | prosaposin | 0.172 | ||
| MYO10 | myosin X | 0.172 | ||
| PLEC | plectin | 0.168 | ||
| GPNMB | glycoprotein (transmembrane) nmb | 0.134 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.133 | ||
| MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 0.131 | Human | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.129 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.112 | ||
| ANXA5 | annexin A5 | 0.096 | ||
| GLRX | glutaredoxin (thioltransferase) | 0.094 | ||
| GRN | granulin | 0.079 | ||
| CSTA | cystatin A (stefin A) | 0.073 | ||
| CTSD | cathepsin D | 0.071 | ||
| LIMK1 | LIM domain kinase 1 | 0.070 | ||
| ITGA6 | integrin, alpha 6 | 0.070 | ||
| COL17A1 | collagen, type XVII, alpha 1 | 0.063 | ||
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.059 | Human | |
| BMP1 | bone morphogenetic protein 1 | 0.056 | ||
| LUM | lumican | 0.049 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.048 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.045 | Mouse Rat | |
| CD9 | CD9 molecule | 0.045 | ||
| HEXB | hexosaminidase B (beta polypeptide) | 0.044 | ||
| ENG | endoglin | 0.044 | ||
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.044 | Human | |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.040 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.038 | ||
| FAP | fibroblast activation protein, alpha | 0.035 | ||
| CTSB | cathepsin B | 0.035 | ||
| LAMC2 | laminin, gamma 2 | 0.032 | ||
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.031 | ||
| MAN2B1 | mannosidase, alpha, class 2B, member 1 | 0.030 | ||
| SRGN | serglycin | 0.029 | ||
| MMP13 | matrix metallopeptidase 13 (collagenase 3) | 0.026 | ||
| CD81 | CD81 molecule | 0.025 | ||
| PLAU | plasminogen activator, urokinase | 0.024 | ||
| B2M | beta-2-microglobulin | 0.024 | ||
| SPHK1 | sphingosine kinase 1 | 0.024 | ||
| CD68 | CD68 molecule | 0.024 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.022 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.021 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.021 | ||
| CST2 | cystatin SA | 0.020 | Human | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.020 | ||
| ECM1 | extracellular matrix protein 1 | 0.018 | ||
| HLA-A | major histocompatibility complex, class I, A | 0.018 | ||
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.017 | ||
| CST4 | cystatin S | 0.016 | Human | |
| INHBA | inhibin, beta A | 0.016 | ||
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) | 0.016 | ||
| LRRC15 | leucine rich repeat containing 15 | 0.016 | ||
| THBS2 | thrombospondin 2 | 0.016 | ||
| IFI30 | interferon, gamma-inducible protein 30 | 0.014 | ||
| ITGB1BP1 | integrin beta 1 binding protein 1 | 0.014 | ||
| ANGPTL4 | angiopoietin-like 4 | 0.013 | ||
| CSTB | cystatin B (stefin B) | 0.013 | ||
| CTSL1 | cathepsin L1 | 0.013 | ||
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.012 | ||
| CD163 | CD163 molecule | 0.012 | ||
| LOXL2 | lysyl oxidase-like 2 | 0.012 | ||
| TNC | tenascin C | 0.011 | ||
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.011 | ||
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.011 | ||
| SQRDL | sulfide quinone reductase-like (yeast) | 0.011 | ||
| CST1 | cystatin SN | 0.010 | Human | |
| THBS1 | thrombospondin 1 | 0.010 | ||
| POSTN | periostin, osteoblast specific factor | 0.010 | ||
| CLEC4A | C-type lectin domain family 4, member A | 0.010 | ||
| KCND2 | potassium voltage-gated channel, Shal-related subfamily, member 2 | 0.010 |