IMP
Process View
regulation of alkaline phosphatase activity
Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of alkaline phosphatase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SMAD2 | SMAD family member 2 | 0.984 | ||
| SMAD1 | SMAD family member 1 | 0.729 | ||
| SORBS1 | sorbin and SH3 domain containing 1 | 0.598 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.575 | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.503 | ||
| SMAD7 | SMAD family member 7 | 0.196 | ||
| ENG | endoglin | 0.188 | ||
| HDAC4 | histone deacetylase 4 | 0.180 | ||
| SMAD9 | SMAD family member 9 | 0.178 | ||
| FSTL1 | follistatin-like 1 | 0.159 | ||
| HDAC9 | histone deacetylase 9 | 0.119 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.108 | ||
| MEF2A | myocyte enhancer factor 2A | 0.101 | ||
| EPAS1 | endothelial PAS domain protein 1 | 0.086 | ||
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.081 | Human | |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.065 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.053 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.046 | ||
| CXXC5 | CXXC finger protein 5 | 0.045 | ||
| SKIL | SKI-like oncogene | 0.043 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.043 | ||
| ITGA8 | integrin, alpha 8 | 0.041 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.041 | ||
| CD22 | CD22 molecule | 0.036 | ||
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.035 | ||
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.034 | Human | |
| ACVR2B | activin A receptor, type IIB | 0.034 | ||
| EP300 | E1A binding protein p300 | 0.029 | ||
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.028 | ||
| FOXO3 | forkhead box O3 | 0.027 | ||
| DEDD | death effector domain containing | 0.025 | ||
| MYLK2 | myosin light chain kinase 2 | 0.024 | ||
| HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.024 | ||
| BMP2 | bone morphogenetic protein 2 | 0.024 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.023 | ||
| THBS1 | thrombospondin 1 | 0.022 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.022 | ||
| SP1 | Sp1 transcription factor | 0.022 | ||
| CSNK1D | casein kinase 1, delta | 0.021 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.020 | ||
| FHOD3 | formin homology 2 domain containing 3 | 0.020 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.020 | ||
| HDAC7 | histone deacetylase 7 | 0.020 | ||
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.020 | ||
| APP | amyloid beta (A4) precursor protein | 0.018 | ||
| NOVA1 | neuro-oncological ventral antigen 1 | 0.017 | ||
| BMP4 | bone morphogenetic protein 4 | 0.016 | ||
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.016 | ||
| ING2 | inhibitor of growth family, member 2 | 0.016 | ||
| SERTAD1 | SERTA domain containing 1 | 0.016 | ||
| TGFBR3 | transforming growth factor, beta receptor III | 0.015 | ||
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.015 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.014 | ||
| TRIM62 | tripartite motif containing 62 | 0.014 | ||
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.014 | ||
| DACH1 | dachshund homolog 1 (Drosophila) | 0.014 | ||
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.014 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.014 | ||
| PLCD3 | phospholipase C, delta 3 | 0.013 | ||
| ITGA6 | integrin, alpha 6 | 0.013 | ||
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.013 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.013 | ||
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | 0.013 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.013 | ||
| SORBS2 | sorbin and SH3 domain containing 2 | 0.013 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.012 | ||
| TSPAN7 | tetraspanin 7 | 0.012 | ||
| MCM3AP | minichromosome maintenance complex component 3 associated protein | 0.012 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.012 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.012 | ||
| CELF2 | CUGBP, Elav-like family member 2 | 0.012 | ||
| BDNF | brain-derived neurotrophic factor | 0.012 | ||
| SLC4A4 | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 0.012 | ||
| HSF4 | heat shock transcription factor 4 | 0.011 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.011 | ||
| DOCK9 | dedicator of cytokinesis 9 | 0.011 | ||
| CA4 | carbonic anhydrase IV | 0.011 | ||
| SETBP1 | SET binding protein 1 | 0.011 | ||
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.011 | ||
| LRMP | lymphoid-restricted membrane protein | 0.011 | ||
| GLP1R | glucagon-like peptide 1 receptor | 0.011 | ||
| PLXNB1 | plexin B1 | 0.011 | ||
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.011 | ||
| FST | follistatin | 0.011 | ||
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.011 | ||
| PCDH17 | protocadherin 17 | 0.010 | ||
| PRDM4 | PR domain containing 4 | 0.010 | ||
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.010 | ||
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.010 | ||
| RNF122 | ring finger protein 122 | 0.010 | ||
| C10orf54 | chromosome 10 open reading frame 54 | 0.010 | ||
| THSD7A | thrombospondin, type I, domain containing 7A | 0.010 |