IMP

Process View

Homo sapiens

10 genes annotated in human

positive regulation of camp mediated signaling

Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of camp mediated signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of camp mediated signaling" (in gray)

Name	Description	Probability	Func Analog Organism
MPDZ	multiple PDZ domain protein	1.000
IL8	interleukin 8	0.984	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.981	Human
CCL5	chemokine (C-C motif) ligand 5	0.976
CCR5	chemokine (C-C motif) receptor 5	0.973	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.962	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.955
ARRB1	arrestin, beta 1	0.945
CXCL2	chemokine (C-X-C motif) ligand 2	0.889	Human
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.782
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.780
CXCL11	chemokine (C-X-C motif) ligand 11	0.749
CCL20	chemokine (C-C motif) ligand 20	0.739
TBXA2R	thromboxane A2 receptor	0.696	Human
IFNG	interferon, gamma	0.543
IL6	interleukin 6 (interferon, beta 2)	0.479
IL1B	interleukin 1, beta	0.470
CXCL5	chemokine (C-X-C motif) ligand 5	0.355	Human
CCR2	chemokine (C-C motif) receptor 2	0.348	Human
CCL22	chemokine (C-C motif) ligand 22	0.340
PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	0.338
CXCL10	chemokine (C-X-C motif) ligand 10	0.324
DPP4	dipeptidyl-peptidase 4	0.290
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.267
CXCR3	chemokine (C-X-C motif) receptor 3	0.199
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.196
NCF2	neutrophil cytosolic factor 2	0.148
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.145
CCL8	chemokine (C-C motif) ligand 8	0.130
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.127	Human
CCL4	chemokine (C-C motif) ligand 4	0.119
CCL11	chemokine (C-C motif) ligand 11	0.115
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.107
CCR7	chemokine (C-C motif) receptor 7	0.097	Human
IL10	interleukin 10	0.084
CXCR5	chemokine (C-X-C motif) receptor 5	0.078	Human
CCL2	chemokine (C-C motif) ligand 2	0.077
CCL19	chemokine (C-C motif) ligand 19	0.074
CXCL13	chemokine (C-X-C motif) ligand 13	0.073
UBD	ubiquitin D	0.072
CXCR2	chemokine (C-X-C motif) receptor 2	0.070	Human
CCL7	chemokine (C-C motif) ligand 7	0.068
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.068
IL2RB	interleukin 2 receptor, beta	0.062
CXCL9	chemokine (C-X-C motif) ligand 9	0.061
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.049
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.047	Human
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.044
RAP1A	RAP1A, member of RAS oncogene family	0.043
CD40LG	CD40 ligand	0.042
ARRDC3	arrestin domain containing 3	0.040
GPR6	G protein-coupled receptor 6	0.038
CCR4	chemokine (C-C motif) receptor 4	0.037	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.036
SSTR2	somatostatin receptor 2	0.033	Human
PTEN	phosphatase and tensin homolog	0.032
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.032
PF4	platelet factor 4	0.032
TLR2	toll-like receptor 2	0.030
PF4V1	platelet factor 4 variant 1	0.030	Human
SSTR3	somatostatin receptor 3	0.030	Human
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.027
IL1R2	interleukin 1 receptor, type II	0.026
GHRHR	growth hormone releasing hormone receptor	0.026
CCL3	chemokine (C-C motif) ligand 3	0.026
IL6R	interleukin 6 receptor	0.024
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.022	Human
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.021
BCL2A1	BCL2-related protein A1	0.021
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.021
CXCR1	chemokine (C-X-C motif) receptor 1	0.021	Human
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.020
CCR9	chemokine (C-C motif) receptor 9	0.019	Human
NCF1	neutrophil cytosolic factor 1	0.019
CLEC7A	C-type lectin domain family 7, member A	0.019
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.019
OPRD1	opioid receptor, delta 1	0.019	Human
PKN2	protein kinase N2	0.018
NUCB1	nucleobindin 1	0.017
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.017
TNF	tumor necrosis factor	0.017
OPRM1	opioid receptor, mu 1	0.017
GNG2	guanine nucleotide binding protein (G protein), gamma 2	0.016
IRF4	interferon regulatory factor 4	0.015
SOD2	superoxide dismutase 2, mitochondrial	0.015
GPSM2	G-protein signaling modulator 2	0.015
ADRB1	adrenergic, beta-1-, receptor	0.015
IL4	interleukin 4	0.015
SELL	selectin L	0.014
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.014
CCL13	chemokine (C-C motif) ligand 13	0.013
AQP9	aquaporin 9	0.013
IL1F5	interleukin 1 family, member 5 (delta)	0.013
IL1A	interleukin 1, alpha	0.013
MAPK10	mitogen-activated protein kinase 10	0.013
CCR6	chemokine (C-C motif) receptor 6	0.013	Human
SELE	selectin E	0.013
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.013
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.012
CCL1	chemokine (C-C motif) ligand 1	0.012
IL7R	interleukin 7 receptor	0.012
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.012
CMTM6	CKLF-like MARVEL transmembrane domain containing 6	0.012
GP5	glycoprotein V (platelet)	0.012
TFEC	transcription factor EC	0.012
SLAMF7	SLAM family member 7	0.011
HBA2	hemoglobin, alpha 2	0.011
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.011
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.011
PTAFR	platelet-activating factor receptor	0.011
S100A12	S100 calcium binding protein A12	0.011
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.011
IDO1	indoleamine 2,3-dioxygenase 1	0.011
OASL	2'-5'-oligoadenylate synthetase-like	0.011
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.010	Human
PLEK	pleckstrin	0.010
CCR1	chemokine (C-C motif) receptor 1	0.010	Human
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.010
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.010	Human