IMP

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Homo sapiens

3 genes annotated in human

activation of mapk activity by adrenergic receptor signaling pathway

The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, followed by the activation of a MAP kinase.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "activation of mapk activity by adrenergic receptor signaling pathway"

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Name	Description	Probability	Func Analog Organism
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1.000
MPDZ	multiple PDZ domain protein	1.000
ARRDC3	arrestin domain containing 3	0.969
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.878
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.861
TBC1D10A	TBC1 domain family, member 10A	0.818
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.381
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.351	Human
BAI1	brain-specific angiogenesis inhibitor 1	0.242
SSTR3	somatostatin receptor 3	0.237
TSHR	thyroid stimulating hormone receptor	0.196
LNX1	ligand of numb-protein X 1	0.177
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.173
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.159
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.136
DRD1	dopamine receptor D1	0.123	Human
GHRHR	growth hormone releasing hormone receptor	0.109
PTPRA	protein tyrosine phosphatase, receptor type, A	0.109
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.106
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.090	Human
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.077	Human
SRCIN1	SRC kinase signaling inhibitor 1	0.075
PTEN	phosphatase and tensin homolog	0.074
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.073
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.066
ADRA2B	adrenergic, alpha-2B-, receptor	0.066
AQP7	aquaporin 7	0.065
GRM5	glutamate receptor, metabotropic 5	0.063
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.060
GPR6	G protein-coupled receptor 6	0.056
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.053
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.053
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.051
ADAM15	ADAM metallopeptidase domain 15	0.049
CHRNB4	cholinergic receptor, nicotinic, beta 4	0.048
ADRB3	adrenergic, beta-3-, receptor	0.047	Human
FEZF2	FEZ family zinc finger 2	0.046
DLG4	discs, large homolog 4 (Drosophila)	0.045
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.044
HTR6	5-hydroxytryptamine (serotonin) receptor 6	0.044
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.043
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.043
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.041
RAB26	RAB26, member RAS oncogene family	0.040
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.039
NXPH3	neurexophilin 3	0.039
RELN	reelin	0.038
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.038	Human
PRODH2	proline dehydrogenase (oxidase) 2	0.037
COPG2	coatomer protein complex, subunit gamma 2	0.036
DNM1	dynamin 1	0.036
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.036
SPRR2A	small proline-rich protein 2A	0.035
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.035
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.035
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.035
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.034
DSCAML1	Down syndrome cell adhesion molecule like 1	0.034
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.033
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.033
KRT33B	keratin 33B	0.032
RHO	rhodopsin	0.032
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.031
UNC13A	unc-13 homolog A (C. elegans)	0.030
CALCR	calcitonin receptor	0.030
ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	0.030
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.029
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.029
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	0.029
AFF2	AF4/FMR2 family, member 2	0.029
NTSR1	neurotensin receptor 1 (high affinity)	0.028
THPO	thrombopoietin	0.028
MMP17	matrix metallopeptidase 17 (membrane-inserted)	0.028
VIPR2	vasoactive intestinal peptide receptor 2	0.028
ADRA1A	adrenergic, alpha-1A-, receptor	0.028
OPCML	opioid binding protein/cell adhesion molecule-like	0.027
PLA2G1B	phospholipase A2, group IB (pancreas)	0.027
CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.027
CCK	cholecystokinin	0.027
LEP	leptin	0.026
CLCN1	chloride channel 1, skeletal muscle	0.026
SCTR	secretin receptor	0.025
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.025	Human
HRH3	histamine receptor H3	0.025
CCR3	chemokine (C-C motif) receptor 3	0.025
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.025
SLC18A1	solute carrier family 18 (vesicular monoamine), member 1	0.024
ADORA1	adenosine A1 receptor	0.024
KRT9	keratin 9	0.024
SPTB	spectrin, beta, erythrocytic	0.024
CDX2	caudal type homeobox 2	0.024
P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3	0.024
GIF	gastric intrinsic factor (vitamin B synthesis)	0.024
NPY2R	neuropeptide Y receptor Y2	0.023
MUC1	mucin 1, cell surface associated	0.023
CRHBP	corticotropin releasing hormone binding protein	0.023
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.023
DLGAP3	discs, large (Drosophila) homolog-associated protein 3	0.023
EMX1	empty spiracles homeobox 1	0.023
RGS4	regulator of G-protein signaling 4	0.023
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	0.023	Human
RIMS4	regulating synaptic membrane exocytosis 4	0.023
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.023
GLP1R	glucagon-like peptide 1 receptor	0.022
CHRNG	cholinergic receptor, nicotinic, gamma	0.022
OPRL1	opiate receptor-like 1	0.022
WNT8B	wingless-type MMTV integration site family, member 8B	0.021
SLC14A2	solute carrier family 14 (urea transporter), member 2	0.021
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.021
CHRND	cholinergic receptor, nicotinic, delta	0.021
CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	0.021
RASL10A	RAS-like, family 10, member A	0.021
MUSK	muscle, skeletal, receptor tyrosine kinase	0.021
PADI4	peptidyl arginine deiminase, type IV	0.021
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.021
CTRC	chymotrypsin C (caldecrin)	0.021
TNP2	transition protein 2 (during histone to protamine replacement)	0.020
BFSP1	beaded filament structural protein 1, filensin	0.020
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.020
IL6R	interleukin 6 receptor	0.020
KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	0.020
YAP1	Yes-associated protein 1	0.020
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	0.020	Human
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.020
GPR27	G protein-coupled receptor 27	0.020
NOS2	nitric oxide synthase 2, inducible	0.020
CCKBR	cholecystokinin B receptor	0.020
NELL1	NEL-like 1 (chicken)	0.020
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.019
TBX5	T-box 5	0.019
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.019
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.019
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	0.019
GPC5	glypican 5	0.019
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.019
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.018
OR10H1	olfactory receptor, family 10, subfamily H, member 1	0.018
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.018
FGF6	fibroblast growth factor 6	0.018
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.018
GPR37L1	G protein-coupled receptor 37 like 1	0.018
NPY1R	neuropeptide Y receptor Y1	0.018
SFRP5	secreted frizzled-related protein 5	0.018
NMUR1	neuromedin U receptor 1	0.018
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.018
DGKQ	diacylglycerol kinase, theta 110kDa	0.018
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.018
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.017
NPPC	natriuretic peptide C	0.017
CPLX2	complexin 2	0.017
ADRB2	adrenergic, beta-2-, receptor, surface	0.017	Human
CRHR1	corticotropin releasing hormone receptor 1	0.017
PTPRR	protein tyrosine phosphatase, receptor type, R	0.017
PLD2	phospholipase D2	0.017
ADRA1D	adrenergic, alpha-1D-, receptor	0.017
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.017
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.017
TREH	trehalase (brush-border membrane glycoprotein)	0.017
CCL11	chemokine (C-C motif) ligand 11	0.017
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.016
FGF18	fibroblast growth factor 18	0.016
PYY	peptide YY	0.016
DCC	deleted in colorectal carcinoma	0.016
SCN2A	sodium channel, voltage-gated, type II, alpha subunit	0.016
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.016
NEUROG2	neurogenin 2	0.016
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.016
LILRA4	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4	0.016
GFRA1	GDNF family receptor alpha 1	0.016
TRH	thyrotropin-releasing hormone	0.016
ALPPL2	alkaline phosphatase, placental-like 2	0.016
REPS2	RALBP1 associated Eps domain containing 2	0.016
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.016
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.016
PDE1B	phosphodiesterase 1B, calmodulin-dependent	0.016
LGI1	leucine-rich, glioma inactivated 1	0.016
TG	thyroglobulin	0.016
CNTFR	ciliary neurotrophic factor receptor	0.016
GLRA1	glycine receptor, alpha 1	0.015
PTPRU	protein tyrosine phosphatase, receptor type, U	0.015
DLX5	distal-less homeobox 5	0.015
CDH8	cadherin 8, type 2	0.015
SMR3A	submaxillary gland androgen regulated protein 3A	0.015
CA4	carbonic anhydrase IV	0.015
HRH2	histamine receptor H2	0.015	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.015
NPY5R	neuropeptide Y receptor Y5	0.015
GFRA2	GDNF family receptor alpha 2	0.015
GP5	glycoprotein V (platelet)	0.015
POU3F2	POU class 3 homeobox 2	0.015
TNNI3	troponin I type 3 (cardiac)	0.015
OR51E2	olfactory receptor, family 51, subfamily E, member 2	0.015
SCN1B	sodium channel, voltage-gated, type I, beta	0.015
FOXI1	forkhead box I1	0.015
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.015
ACCN1	amiloride-sensitive cation channel 1, neuronal	0.015
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.015
ADRBK1	adrenergic, beta, receptor kinase 1	0.015
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.015
AVPR1B	arginine vasopressin receptor 1B	0.015
PNLIPRP1	pancreatic lipase-related protein 1	0.014
APOC3	apolipoprotein C-III	0.014
OPRK1	opioid receptor, kappa 1	0.014
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.014
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.014
P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	0.014
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.014
B4GALNT1	beta-1,4-N-acetyl-galactosaminyl transferase 1	0.014
AQP2	aquaporin 2 (collecting duct)	0.014
ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma	0.014
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.014
ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	0.014
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.013
PCSK2	proprotein convertase subtilisin/kexin type 2	0.013
NOVA2	neuro-oncological ventral antigen 2	0.013
GPR26	G protein-coupled receptor 26	0.013
LPAR4	lysophosphatidic acid receptor 4	0.013
WNT11	wingless-type MMTV integration site family, member 11	0.013
MYF6	myogenic factor 6 (herculin)	0.013
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.013
FOXF2	forkhead box F2	0.013
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.013
KLK3	kallikrein-related peptidase 3	0.013
RET	ret proto-oncogene	0.013
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.013
SIRPB1	signal-regulatory protein beta 1	0.013
AKAP12	A kinase (PRKA) anchor protein 12	0.013
GABRA6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	0.013
PNMT	phenylethanolamine N-methyltransferase	0.013
SLC16A8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.013
JPH3	junctophilin 3	0.013
ACRV1	acrosomal vesicle protein 1	0.013
CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	0.013
UNC5C	unc-5 homolog C (C. elegans)	0.013
WNT7A	wingless-type MMTV integration site family, member 7A	0.013
ONECUT2	one cut homeobox 2	0.013
CRHR2	corticotropin releasing hormone receptor 2	0.013
NEUROG1	neurogenin 1	0.013
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.013
PRM2	protamine 2	0.013
ADAM2	ADAM metallopeptidase domain 2	0.013
IL10	interleukin 10	0.012
RIMS1	regulating synaptic membrane exocytosis 1	0.012
FGF8	fibroblast growth factor 8 (androgen-induced)	0.012
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.012
LRIT1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	0.012
ATP10A	ATPase, class V, type 10A	0.012
IHH	Indian hedgehog	0.012
CADM3	cell adhesion molecule 3	0.012
TFF2	trefoil factor 2	0.012
PRDM8	PR domain containing 8	0.012
PPY	pancreatic polypeptide	0.012
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.012
F2RL3	coagulation factor II (thrombin) receptor-like 3	0.012
TACR2	tachykinin receptor 2	0.012
OMD	osteomodulin	0.012
ALPL	alkaline phosphatase, liver/bone/kidney	0.012
OPRM1	opioid receptor, mu 1	0.012
MAG	myelin associated glycoprotein	0.012
GRIK4	glutamate receptor, ionotropic, kainate 4	0.012
EMX2	empty spiracles homeobox 2	0.012
GFAP	glial fibrillary acidic protein	0.012
SCN2B	sodium channel, voltage-gated, type II, beta	0.012
CXCR1	chemokine (C-X-C motif) receptor 1	0.012
EFNB3	ephrin-B3	0.012
PAX6	paired box 6	0.012
KCNT1	potassium channel, subfamily T, member 1	0.012
FGF4	fibroblast growth factor 4	0.012
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.012
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.012
TAGLN3	transgelin 3	0.012
TBR1	T-box, brain, 1	0.012
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.012
NXNL1	nucleoredoxin-like 1	0.012
BMP8A	bone morphogenetic protein 8a	0.012
PADI1	peptidyl arginine deiminase, type I	0.012
GCM1	glial cells missing homolog 1 (Drosophila)	0.012
OPRD1	opioid receptor, delta 1	0.012
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.012
MIP	major intrinsic protein of lens fiber	0.012
FKBP6	FK506 binding protein 6, 36kDa	0.012
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.011
SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.011
ZNF157	zinc finger protein 157	0.011
DPEP3	dipeptidase 3	0.011
GRM7	glutamate receptor, metabotropic 7	0.011
PDE3A	phosphodiesterase 3A, cGMP-inhibited	0.011
MTMR7	myotubularin related protein 7	0.011
UTS2R	urotensin 2 receptor	0.011
ANXA13	annexin A13	0.011
COMP	cartilage oligomeric matrix protein	0.011
AANAT	aralkylamine N-acetyltransferase	0.011
ZNF132	zinc finger protein 132	0.011
GRIA3	glutamate receptor, ionotrophic, AMPA 3	0.011
PTK2	PTK2 protein tyrosine kinase 2	0.011
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.011
KL	klotho	0.011
KRT2	keratin 2	0.011
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.011
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.011
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.011
NPAS1	neuronal PAS domain protein 1	0.011
CRYBB1	crystallin, beta B1	0.011
EGR4	early growth response 4	0.011
SCN7A	sodium channel, voltage-gated, type VII, alpha	0.011
SSTR1	somatostatin receptor 1	0.011
CHIA	chitinase, acidic	0.011
AHSG	alpha-2-HS-glycoprotein	0.011
DOC2B	double C2-like domains, beta	0.011
STMN2	stathmin-like 2	0.011
PCDH8	protocadherin 8	0.011
MEP1B	meprin A, beta	0.011
CRP	C-reactive protein, pentraxin-related	0.011
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.011
MUC6	mucin 6, oligomeric mucus/gel-forming	0.011
CASR	calcium-sensing receptor	0.011
GRIK1	glutamate receptor, ionotropic, kainate 1	0.011
INA	internexin neuronal intermediate filament protein, alpha	0.011
KCNK13	potassium channel, subfamily K, member 13	0.011
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.010
F2RL2	coagulation factor II (thrombin) receptor-like 2	0.010
FOXF1	forkhead box F1	0.010
NCAN	neurocan	0.010
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.010
DARC	Duffy blood group, chemokine receptor	0.010
OCA2	oculocutaneous albinism II	0.010
PSG7	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	0.010
CRYGD	crystallin, gamma D	0.010
KLHL1	kelch-like 1 (Drosophila)	0.010
MAS1	MAS1 oncogene	0.010
SELE	selectin E	0.010
LHX2	LIM homeobox 2	0.010
NPPA	natriuretic peptide A	0.010
ADRA2A	adrenergic, alpha-2A-, receptor	0.010
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.010
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.010
CDH22	cadherin 22, type 2	0.010
SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.010
MYOD1	myogenic differentiation 1	0.010
AQP6	aquaporin 6, kidney specific	0.010
PKNOX2	PBX/knotted 1 homeobox 2	0.010
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.010
DLGAP4	discs, large (Drosophila) homolog-associated protein 4	0.010
CRISP3	cysteine-rich secretory protein 3	0.010
GJA5	gap junction protein, alpha 5, 40kDa	0.010
SHOX2	short stature homeobox 2	0.010
IL13	interleukin 13	0.010
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.010
GCGR	glucagon receptor	0.010
CCL24	chemokine (C-C motif) ligand 24	0.010
GYPA	glycophorin A (MNS blood group)	0.010
KCNH3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.010
NKX2-1	NK2 homeobox 1	0.010
FOXB1	forkhead box B1	0.010
BFSP2	beaded filament structural protein 2, phakinin	0.010
GH2	growth hormone 2	0.010
LHX1	LIM homeobox 1	0.010