IMP

Process View

Homo sapiens

8 genes annotated in human

germ cell development

The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "germ cell development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "germ cell development" (in gray)

Name	Description	Probability	Func Analog Organism
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.242	Fly
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.127	Fly
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.108	Fly
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.097	Fly
CDK2	cyclin-dependent kinase 2	0.092
EGFR	epidermal growth factor receptor	0.077	Fly
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.071	Fly
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.063	Fly
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.062	Fly
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.052	Fly
QKI	quaking homolog, KH domain RNA binding (mouse)	0.052	Mouse Worm
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.048	Fly
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.048	Fly
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.038	Worm
CREBBP	CREB binding protein	0.038	Worm
TP53	tumor protein p53	0.036	Fly
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.032	Fly
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	0.031	Worm
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.029	Mouse Fly
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.028
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.027	Worm
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.027	Fly
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.026	Worm
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.025
BRCA2	breast cancer 2, early onset	0.024	Mouse
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.021	Fly
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.020
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.020	Fly
SMAD4	SMAD family member 4	0.020	Fly
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.018
PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	0.018
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.017
EIF4A3	eukaryotic translation initiation factor 4A3	0.017	Worm Fly
CCNB1	cyclin B1	0.017	Rat Worm
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.016	Fly
GRB2	growth factor receptor-bound protein 2	0.016
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.016	Fly
PTBP1	polypyrimidine tract binding protein 1	0.015	Fly
TARDBP	TAR DNA binding protein	0.014
SRSF1	serine/arginine-rich splicing factor 1	0.014
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.014
SNW1	SNW domain containing 1	0.014	Worm
MCM7	minichromosome maintenance complex component 7	0.013
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.013
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.013
SP1	Sp1 transcription factor	0.013
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.013
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.013	Worm
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.013
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.013	Worm
RPA1	replication protein A1, 70kDa	0.013
RBM39	RNA binding motif protein 39	0.012
EP300	E1A binding protein p300	0.012	Worm
PNN	pinin, desmosome associated protein	0.012
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.012
RB1	retinoblastoma 1	0.012
SRSF3	serine/arginine-rich splicing factor 3	0.012	Worm
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.012	Fly
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.012	Mouse Fly
INSR	insulin receptor	0.012	Fly
SRSF2	serine/arginine-rich splicing factor 2	0.012
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.011	Worm Fly
WIPF1	WAS/WASL interacting protein family, member 1	0.011
SNRPE	small nuclear ribonucleoprotein polypeptide E	0.011	Worm
TCP1	t-complex 1	0.011
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.011	Worm Fly
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.011
ATF2	activating transcription factor 2	0.011
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.010
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.010	Fly
CCNA2	cyclin A2	0.010
ESR1	estrogen receptor 1	0.010