IMP
Process View
positive regulation of type i interferon mediated signaling pathway
Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of type i interferon mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.804 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.552 | ||
| CREBBP | CREB binding protein | 0.203 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.188 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.175 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.133 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.120 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.100 | ||
| HTT | huntingtin | 0.063 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.058 | ||
| TMEM173 | transmembrane protein 173 | 0.054 | ||
| IRF3 | interferon regulatory factor 3 | 0.051 | Mouse | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.051 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.051 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.048 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.032 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.031 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.028 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.022 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.022 | ||
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.022 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.022 | ||
| TBK1 | TANK-binding kinase 1 | 0.020 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.019 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.019 | ||
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.018 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.017 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.015 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.014 | ||
| IRF7 | interferon regulatory factor 7 | 0.013 | Mouse | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.013 | ||
| AZI2 | 5-azacytidine induced 2 | 0.013 | ||
| DAXX | death-domain associated protein | 0.012 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.012 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.011 | ||
| TADA3 | transcriptional adaptor 3 | 0.011 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.010 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.010 |