IMP

Process View

Homo sapiens

1 genes annotated in human

schwann cell development

The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "schwann cell development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "schwann cell development" (in gray)

Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000	Zebrafish
EGFR	epidermal growth factor receptor	0.990
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.849	Zebrafish
INADL	InaD-like (Drosophila)	0.417
SOX10	SRY (sex determining region Y)-box 10	0.262
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.238
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.218
PAX3	paired box 3	0.194
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.184
PTK6	PTK6 protein tyrosine kinase 6	0.164
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.150
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.101
DMD	dystrophin	0.078
GRB7	growth factor receptor-bound protein 7	0.074
UTRN	utrophin	0.069
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.057
CDK19	cyclin-dependent kinase 19	0.057
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.057
DCTN1	dynactin 1	0.048
YAP1	Yes-associated protein 1	0.047
SH3RF1	SH3 domain containing ring finger 1	0.046
MAPT	microtubule-associated protein tau	0.043
AMOTL2	angiomotin like 2	0.043
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.043
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.042
JAM2	junctional adhesion molecule 2	0.041
PARVA	parvin, alpha	0.036
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.035
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.033
SPRR2A	small proline-rich protein 2A	0.033
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.033
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.031
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.030
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.029
DTNA	dystrobrevin, alpha	0.029
MED29	mediator complex subunit 29	0.029
SH3BP4	SH3-domain binding protein 4	0.028
DDR2	discoidin domain receptor tyrosine kinase 2	0.027
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.027
VAV3	vav 3 guanine nucleotide exchange factor	0.027
KCTD1	potassium channel tetramerisation domain containing 1	0.027
MED16	mediator complex subunit 16	0.026
GAB2	GRB2-associated binding protein 2	0.026
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.025
TNRC6A	trinucleotide repeat containing 6A	0.025
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.024
TNS3	tensin 3	0.023
VAV2	vav 2 guanine nucleotide exchange factor	0.023
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.022
MUC1	mucin 1, cell surface associated	0.021
TJP3	tight junction protein 3 (zona occludens 3)	0.021
CDH5	cadherin 5, type 2 (vascular endothelium)	0.021
LAMA5	laminin, alpha 5	0.020
F11R	F11 receptor	0.020
CABLES1	Cdk5 and Abl enzyme substrate 1	0.019
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.019
ANXA9	annexin A9	0.019
PARVB	parvin, beta	0.019
MED24	mediator complex subunit 24	0.019
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.018
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.018
LIMS1	LIM and senescent cell antigen-like domains 1	0.018
INSR	insulin receptor	0.017
AMOT	angiomotin	0.017
JAM3	junctional adhesion molecule 3	0.016
APP	amyloid beta (A4) precursor protein	0.015
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.015
CCL14	chemokine (C-C motif) ligand 14	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.015
TARBP2	TAR (HIV-1) RNA binding protein 2	0.015
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.015
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.015
GAB1	GRB2-associated binding protein 1	0.015
MEOX2	mesenchyme homeobox 2	0.014
HIPK2	homeodomain interacting protein kinase 2	0.014
SKIL	SKI-like oncogene	0.014
TNRC6C	trinucleotide repeat containing 6C	0.014
ZMYM3	zinc finger, MYM-type 3	0.014
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.014
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.013
NPIP	nuclear pore complex interacting protein	0.013
IGF1R	insulin-like growth factor 1 receptor	0.013
EPHB1	EPH receptor B1	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.013
NCK2	NCK adaptor protein 2	0.012
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.012
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.012
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.012
AMOTL1	angiomotin like 1	0.012
ADAR	adenosine deaminase, RNA-specific	0.012
DTNB	dystrobrevin, beta	0.012
FAM129A	family with sequence similarity 129, member A	0.012
MED13	mediator complex subunit 13	0.012
IRS1	insulin receptor substrate 1	0.012
SMAD4	SMAD family member 4	0.012
SH3BP2	SH3-domain binding protein 2	0.012
PTPRA	protein tyrosine phosphatase, receptor type, A	0.011
LIN7C	lin-7 homolog C (C. elegans)	0.011
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.011
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.011
SRCIN1	SRC kinase signaling inhibitor 1	0.011
KAT2A	K(lysine) acetyltransferase 2A	0.011
BAD	BCL2-associated agonist of cell death	0.011
TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	0.011
RECK	reversion-inducing-cysteine-rich protein with kazal motifs	0.010
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.010
POFUT1	protein O-fucosyltransferase 1	0.010
PPP1R10	protein phosphatase 1, regulatory (inhibitor) subunit 10	0.010
DAB1	disabled homolog 1 (Drosophila)	0.010
ALAS1	aminolevulinate, delta-, synthase 1	0.010
ASXL1	additional sex combs like 1 (Drosophila)	0.010
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.010
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.010
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.010	Mouse
FER	fer (fps/fes related) tyrosine kinase	0.010