IMP
Process View
fatty acid beta oxidation
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "fatty acid beta oxidation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SCP2 | sterol carrier protein 2 | 0.924 | ||
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.916 | Rat Fly | |
| PEX19 | peroxisomal biogenesis factor 19 | 0.817 | ||
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.715 | ||
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 0.489 | ||
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 0.449 | ||
| CAT | catalase | 0.423 | ||
| INSR | insulin receptor | 0.414 | ||
| PEX14 | peroxisomal biogenesis factor 14 | 0.406 | ||
| HADH | hydroxyacyl-CoA dehydrogenase | 0.373 | Rat | |
| NOXA1 | NADPH oxidase activator 1 | 0.292 | ||
| PEX12 | peroxisomal biogenesis factor 12 | 0.245 | ||
| CPT2 | carnitine palmitoyltransferase 2 | 0.223 | ||
| ETFDH | electron-transferring-flavoprotein dehydrogenase | 0.218 | ||
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.169 | Mouse Rat | |
| GRB10 | growth factor receptor-bound protein 10 | 0.118 | ||
| NME2 | non-metastatic cells 2, protein (NM23B) expressed in | 0.113 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.104 | ||
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.104 | ||
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.088 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.088 | ||
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.082 | ||
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.079 | ||
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.070 | ||
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.066 | ||
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.062 | Mouse Fly | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.061 | ||
| SQSTM1 | sequestosome 1 | 0.060 | ||
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.055 | Rat | |
| IRS1 | insulin receptor substrate 1 | 0.048 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.046 | ||
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.044 | ||
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.039 | ||
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.039 | ||
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.039 | ||
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.037 | ||
| PEX3 | peroxisomal biogenesis factor 3 | 0.034 | ||
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.032 | ||
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.032 | ||
| ECI2 | enoyl-CoA delta isomerase 2 | 0.032 | Rat | |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.032 | ||
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | 0.032 | ||
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | 0.030 | ||
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.026 | ||
| C21orf33 | chromosome 21 open reading frame 33 | 0.025 | ||
| MUT | methylmalonyl CoA mutase | 0.025 | ||
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.025 | ||
| NNT | nicotinamide nucleotide transhydrogenase | 0.024 | ||
| CBWD2 | COBW domain containing 2 | 0.023 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.022 | ||
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.022 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.021 | ||
| CYB5A | cytochrome b5 type A (microsomal) | 0.021 | ||
| GBAS | glioblastoma amplified sequence | 0.020 | ||
| RUNX1 | runt-related transcription factor 1 | 0.019 | ||
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.019 | ||
| QARS | glutaminyl-tRNA synthetase | 0.018 | ||
| GATA2 | GATA binding protein 2 | 0.018 | ||
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.018 | ||
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.017 | ||
| TRIM9 | tripartite motif containing 9 | 0.017 | ||
| HRSP12 | heat-responsive protein 12 | 0.017 | ||
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.016 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.016 | ||
| CCL14 | chemokine (C-C motif) ligand 14 | 0.016 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.015 | ||
| CDCP1 | CUB domain containing protein 1 | 0.015 | ||
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 0.015 | ||
| PHKB | phosphorylase kinase, beta | 0.015 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.014 | ||
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.014 | ||
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | 0.014 | ||
| PRKCB | protein kinase C, beta | 0.014 | ||
| ISOC1 | isochorismatase domain containing 1 | 0.013 | ||
| CBR4 | carbonyl reductase 4 | 0.013 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.013 | ||
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.013 | ||
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | 0.013 | ||
| PEX13 | peroxisomal biogenesis factor 13 | 0.013 | ||
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.013 | ||
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.012 | ||
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.012 | ||
| ULK1 | unc-51-like kinase 1 (C. elegans) | 0.012 | ||
| FHOD3 | formin homology 2 domain containing 3 | 0.012 | ||
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.012 | ||
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.012 | ||
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.012 | ||
| LMF2 | lipase maturation factor 2 | 0.012 | ||
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | 0.012 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.012 | ||
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.012 | ||
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | 0.011 | ||
| COQ5 | coenzyme Q5 homolog, methyltransferase (S. cerevisiae) | 0.011 | ||
| PYCARD | PYD and CARD domain containing | 0.011 | ||
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.011 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.011 | ||
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.011 | ||
| KDM1A | lysine (K)-specific demethylase 1A | 0.011 | ||
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.011 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.011 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.010 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.010 |