IMP
Process View
t helper 1 cell differentiation
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "t helper 1 cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IL4R | interleukin 4 receptor | 1.000 | Mouse | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.879 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.853 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.813 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.793 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.663 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.385 | Mouse | |
| IL4 | interleukin 4 | 0.364 | Mouse | |
| IL2RG | interleukin 2 receptor, gamma | 0.327 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.166 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.162 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.115 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.099 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.062 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.058 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.056 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.033 | ||
| TMEM173 | transmembrane protein 173 | 0.032 | ||
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.032 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.026 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.024 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.018 | ||
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.017 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.016 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.015 | ||
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.015 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.013 | ||
| PLXNB2 | plexin B2 | 0.012 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.011 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.011 | ||
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.011 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.011 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.011 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.011 | ||
| PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.010 |