IMP

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Homo sapiens

2 genes annotated in human

Multi-species View

regulation of eosinophil activation

GO:1902566

Any process that modulates the frequency, rate or extent of eosinophil activation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of eosinophil activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of eosinophil activation" (in gray)

Name	Description	Probability	Func Analog Organism
TFF1	trefoil factor 1	1.000
CAV1	caveolin 1, caveolae protein, 22kDa	0.814
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.805
SIGLEC7	sialic acid binding Ig-like lectin 7	0.439
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.322
INADL	InaD-like (Drosophila)	0.314
CAV2	caveolin 2	0.313
CD300C	CD300c molecule	0.253	Human
HK3	hexokinase 3 (white cell)	0.225
NFAM1	NFAT activating protein with ITAM motif 1	0.187
SIGLEC9	sialic acid binding Ig-like lectin 9	0.181
PROCR	protein C receptor, endothelial	0.145
CYTH4	cytohesin 4	0.125
CD33	CD33 molecule	0.112
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.100
TRAF3IP3	TRAF3 interacting protein 3	0.099
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.093
RNASE6	ribonuclease, RNase A family, k6	0.092
SELL	selectin L	0.090
SASH3	SAM and SH3 domain containing 3	0.088
LY86	lymphocyte antigen 86	0.087
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.086
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.078
CXCR6	chemokine (C-X-C motif) receptor 6	0.077
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.076
APOBR	apolipoprotein B receptor	0.072
BIN2	bridging integrator 2	0.069
ASGR2	asialoglycoprotein receptor 2	0.068
CLEC7A	C-type lectin domain family 7, member A	0.065
ADAP2	ArfGAP with dual PH domains 2	0.062
CD1C	CD1c molecule	0.061
CD180	CD180 molecule	0.059
CYBB	cytochrome b-245, beta polypeptide	0.059
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.058
TXNRD1	thioredoxin reductase 1	0.055
CLEC10A	C-type lectin domain family 10, member A	0.054
MSR1	macrophage scavenger receptor 1	0.054
SIGLEC5	sialic acid binding Ig-like lectin 5	0.049
CLEC4A	C-type lectin domain family 4, member A	0.048
TNFAIP8L2	tumor necrosis factor, alpha-induced protein 8-like 2	0.046
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.042
ADORA3	adenosine A3 receptor	0.040
CD48	CD48 molecule	0.040
CLEC5A	C-type lectin domain family 5, member A	0.039
HCST	hematopoietic cell signal transducer	0.039
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.036
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.034
PTEN	phosphatase and tensin homolog	0.032
IL2RB	interleukin 2 receptor, beta	0.032
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.032
CD101	CD101 molecule	0.031
IL10	interleukin 10	0.031
DOK2	docking protein 2, 56kDa	0.031
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.030
TFEC	transcription factor EC	0.030
GPR35	G protein-coupled receptor 35	0.029
FFAR2	free fatty acid receptor 2	0.028
GPR18	G protein-coupled receptor 18	0.028	Human
CCR6	chemokine (C-C motif) receptor 6	0.028
CD300LB	CD300 molecule-like family member b	0.028	Human
CD86	CD86 molecule	0.027
AOAH	acyloxyacyl hydrolase (neutrophil)	0.027
CD1D	CD1d molecule	0.027
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.026
IRF8	interferon regulatory factor 8	0.026
PTPRF	protein tyrosine phosphatase, receptor type, F	0.026
MUC5B	mucin 5B, oligomeric mucus/gel-forming	0.026
ACPT	acid phosphatase, testicular	0.026
CX3CR1	chemokine (C-X3-C motif) receptor 1	0.025
CDCP1	CUB domain containing protein 1	0.025
ABI3	ABI family, member 3	0.025
CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	0.025
ESPNL	espin-like	0.024
DMBT1	deleted in malignant brain tumors 1	0.023
TBXAS1	thromboxane A synthase 1 (platelet)	0.023
GIMAP4	GTPase, IMAP family member 4	0.023
SDS	serine dehydratase	0.023
AQP9	aquaporin 9	0.023
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.022
NLRP3	NLR family, pyrin domain containing 3	0.022
FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	0.022
LRRC25	leucine rich repeat containing 25	0.021
GJA1	gap junction protein, alpha 1, 43kDa	0.021
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.021
CFP	complement factor properdin	0.021
SLAMF7	SLAM family member 7	0.020
MYO1F	myosin IF	0.020
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.020
IL19	interleukin 19	0.020
PVRIG	poliovirus receptor related immunoglobulin domain containing	0.020
MYBPC3	myosin binding protein C, cardiac	0.020
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.019
PARVG	parvin, gamma	0.019
SIGLEC12	sialic acid binding Ig-like lectin 12	0.019
PIK3R6	phosphoinositide-3-kinase, regulatory subunit 6	0.019
GPR84	G protein-coupled receptor 84	0.019
OSCAR	osteoclast associated, immunoglobulin-like receptor	0.019
CMKLR1	chemokine-like receptor 1	0.019
RGS18	regulator of G-protein signaling 18	0.019
S100A12	S100 calcium binding protein A12	0.019
CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	0.019
UTS2R	urotensin 2 receptor	0.018
PNLIPRP1	pancreatic lipase-related protein 1	0.018
IL12RB1	interleukin 12 receptor, beta 1	0.018
XDH	xanthine dehydrogenase	0.018
MEFV	Mediterranean fever	0.018
PADI2	peptidyl arginine deiminase, type II	0.018
CXCR1	chemokine (C-X-C motif) receptor 1	0.018
LY9	lymphocyte antigen 9	0.018
TLR6	toll-like receptor 6	0.017
CXCR3	chemokine (C-X-C motif) receptor 3	0.017
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.017
C19orf59	chromosome 19 open reading frame 59	0.017
GPR171	G protein-coupled receptor 171	0.017
FPR3	formyl peptide receptor 3	0.016
CHIT1	chitinase 1 (chitotriosidase)	0.016
CATSPER1	cation channel, sperm associated 1	0.016
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.016	Human
NLRC4	NLR family, CARD domain containing 4	0.016
APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.016
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.016
CCNDBP1	cyclin D-type binding-protein 1	0.016
SIGLEC8	sialic acid binding Ig-like lectin 8	0.016
FBP1	fructose-1,6-bisphosphatase 1	0.016
KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.016
CXCL9	chemokine (C-X-C motif) ligand 9	0.016
HAVCR2	hepatitis A virus cellular receptor 2	0.016
RELT	RELT tumor necrosis factor receptor	0.016
EMILIN2	elastin microfibril interfacer 2	0.015
PDCD1LG2	programmed cell death 1 ligand 2	0.015
SIGLEC10	sialic acid binding Ig-like lectin 10	0.015
FPR2	formyl peptide receptor 2	0.015
NKG7	natural killer cell group 7 sequence	0.015
SLC22A14	solute carrier family 22, member 14	0.015
P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	0.015
GPBAR1	G protein-coupled bile acid receptor 1	0.015
IPCEF1	interaction protein for cytohesin exchange factors 1	0.015
AVPR1B	arginine vasopressin receptor 1B	0.015
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.015
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.014
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.014
IRF5	interferon regulatory factor 5	0.014
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.014
FPR1	formyl peptide receptor 1	0.014
CD84	CD84 molecule	0.014
GFER	growth factor, augmenter of liver regeneration	0.014
BTNL3	butyrophilin-like 3	0.014
GPR97	G protein-coupled receptor 97	0.014
EDNRB	endothelin receptor type B	0.014
PROM1	prominin 1	0.014
CD8A	CD8a molecule	0.014
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.014
IFNG	interferon, gamma	0.014
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.014
DENND1C	DENN/MADD domain containing 1C	0.014
MYO1A	myosin IA	0.014
PRKCDBP	protein kinase C, delta binding protein	0.014
SIRPB1	signal-regulatory protein beta 1	0.013
TRAT1	T cell receptor associated transmembrane adaptor 1	0.013
GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	0.013
ACPP	acid phosphatase, prostate	0.013
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.013
WFDC6	WAP four-disulfide core domain 6	0.013
ADPRH	ADP-ribosylarginine hydrolase	0.013
NXNL1	nucleoredoxin-like 1	0.013
BSND	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.013
ARHGAP9	Rho GTPase activating protein 9	0.013
TRPM2	transient receptor potential cation channel, subfamily M, member 2	0.013
RNASE3	ribonuclease, RNase A family, 3	0.013
FCRL4	Fc receptor-like 4	0.013
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.013
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.013
C5AR1	complement component 5a receptor 1	0.013
LRRC33	leucine rich repeat containing 33	0.013
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.013
CAMP	cathelicidin antimicrobial peptide	0.013
GBGT1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	0.012
PTAFR	platelet-activating factor receptor	0.012
TMC5	transmembrane channel-like 5	0.012
PLS3	plastin 3	0.012
CCL24	chemokine (C-C motif) ligand 24	0.012
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.012
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.012
NINJ2	ninjurin 2	0.012
SPDEF	SAM pointed domain containing ets transcription factor	0.012
CCR2	chemokine (C-C motif) receptor 2	0.012	Mouse
MAPK15	mitogen-activated protein kinase 15	0.012
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.012
SCGB2A1	secretoglobin, family 2A, member 1	0.012
TMEM92	transmembrane protein 92	0.012
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.012
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.012
LYZL6	lysozyme-like 6	0.012
SH3TC1	SH3 domain and tetratricopeptide repeats 1	0.012
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.012
FCAMR	Fc receptor, IgA, IgM, high affinity	0.012	Human
TNFRSF17	tumor necrosis factor receptor superfamily, member 17	0.012
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.012
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.012
OR10A4	olfactory receptor, family 10, subfamily A, member 4	0.011
TXN	thioredoxin	0.011
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.011
C17orf60	chromosome 17 open reading frame 60	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
CLEC4E	C-type lectin domain family 4, member E	0.011
BTLA	B and T lymphocyte associated	0.011
NLRP12	NLR family, pyrin domain containing 12	0.011
CST4	cystatin S	0.011
SIGLEC15	sialic acid binding Ig-like lectin 15	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.011
RGS13	regulator of G-protein signaling 13	0.011
C1orf116	chromosome 1 open reading frame 116	0.011
TREML2	triggering receptor expressed on myeloid cells-like 2	0.011
IL18RAP	interleukin 18 receptor accessory protein	0.011
CTRL	chymotrypsin-like	0.011
ZBP1	Z-DNA binding protein 1	0.011
F13A1	coagulation factor XIII, A1 polypeptide	0.011
FGD2	FYVE, RhoGEF and PH domain containing 2	0.011
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.011
SPRR2A	small proline-rich protein 2A	0.011
MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.011
PLD4	phospholipase D family, member 4	0.011
BST1	bone marrow stromal cell antigen 1	0.011
C10orf99	chromosome 10 open reading frame 99	0.011
FES	feline sarcoma oncogene	0.011
AMPD1	adenosine monophosphate deaminase 1	0.011
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.011
P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5	0.011
PDE6G	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.011
LRP6	low density lipoprotein receptor-related protein 6	0.011
ZAN	zonadhesin	0.011
XKR8	XK, Kell blood group complex subunit-related family, member 8	0.011
MS4A14	membrane-spanning 4-domains, subfamily A, member 14	0.011
NLRP6	NLR family, pyrin domain containing 6	0.011
GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	0.011
GZMK	granzyme K (granzyme 3; tryptase II)	0.010
GP9	glycoprotein IX (platelet)	0.010
PLEK2	pleckstrin 2	0.010
TJP3	tight junction protein 3 (zona occludens 3)	0.010
LGALS2	lectin, galactoside-binding, soluble, 2	0.010
DRD2	dopamine receptor D2	0.010
CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.010
TMEM180	transmembrane protein 180	0.010
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.010
TMSB4Y	thymosin beta 4, Y-linked	0.010
PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	0.010
PLUNC	palate, lung and nasal epithelium associated	0.010
TAGAP	T-cell activation RhoGTPase activating protein	0.010
MYO1G	myosin IG	0.010
EXOC3L1	exocyst complex component 3-like 1	0.010
C1orf162	chromosome 1 open reading frame 162	0.010
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.010
AMIGO2	adhesion molecule with Ig-like domain 2	0.010
IL1F10	interleukin 1 family, member 10 (theta)	0.010
C20orf114	chromosome 20 open reading frame 114	0.010
SIRPB2	signal-regulatory protein beta 2	0.010
CD38	CD38 molecule	0.010
IGLL5	immunoglobulin lambda-like polypeptide 5	0.010
SNX20	sorting nexin 20	0.010
MNDA	myeloid cell nuclear differentiation antigen	0.010