IMP

Process View

Mus musculus

5 genes annotated in mouse

Multi-species View

tube lumen cavitation

GO:0060605

The formation of a lumen by hollowing out a solid rod or cord.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tube lumen cavitation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tube lumen cavitation" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.999
Gli3	GLI-Kruppel family member GLI3	0.985
Edaradd	EDAR (ectodysplasin-A receptor)-associated death domain	0.971
Trp63	transformation related protein 63	0.939
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.659	Mouse
Cux1	cut-like homeobox 1	0.500
Pax6	paired box gene 6	0.418
Ctnnb1	catenin (cadherin associated protein), beta 1	0.304
Fgf10	fibroblast growth factor 10	0.303
Dsg2	desmoglein 2	0.284
Hoxd13	homeobox D13	0.281
Sox9	SRY-box containing gene 9	0.280
Tcfap2a	transcription factor AP-2, alpha	0.216
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.173
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.161
Pitx1	paired-like homeodomain transcription factor 1	0.132
Fgf9	fibroblast growth factor 9	0.131
Sostdc1	sclerostin domain containing 1	0.113
Isl1	ISL1 transcription factor, LIM/homeodomain	0.111
Tbx15	T-box 15	0.107
Bmp4	bone morphogenetic protein 4	0.104
Prrx1	paired related homeobox 1	0.086
Otx2	orthodenticle homolog 2 (Drosophila)	0.078
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.068
Egfr	epidermal growth factor receptor	0.063
Hoxd11	homeobox D11	0.063
Hoxa10	homeobox A10	0.061
Pax3	paired box gene 3	0.060
Pthlh	parathyroid hormone-like peptide	0.059
Mpzl2	myelin protein zero-like 2	0.056
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.050
Krt8	keratin 8	0.050
Tcfap2c	transcription factor AP-2, gamma	0.045
Sox18	SRY-box containing gene 18	0.041
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.037
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.037
Dcc	deleted in colorectal carcinoma	0.037
Tbx3	T-box 3	0.037
Hoxa13	homeobox A13	0.037
Sox2	SRY-box containing gene 2	0.036
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.035
Traf6	TNF receptor-associated factor 6	0.034
Foxc1	forkhead box C1	0.033
Ivl	involucrin	0.032
Edar	ectodysplasin-A receptor	0.028
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.028
Sfn	stratifin	0.028
Bmp7	bone morphogenetic protein 7	0.027
Twist2	twist homolog 2 (Drosophila)	0.027
Alx4	aristaless-like homeobox 4	0.026
Fgf8	fibroblast growth factor 8	0.024
Pomc	pro-opiomelanocortin-alpha	0.024
Vangl2	vang-like 2 (van gogh, Drosophila)	0.024
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.023
Shh	sonic hedgehog	0.023
Ar	androgen receptor	0.023
Lrp6	low density lipoprotein receptor-related protein 6	0.023
Lgals7	lectin, galactose binding, soluble 7	0.022
Pcdh12	protocadherin 12	0.022
Psapl1	prosaposin-like 1	0.021
Ifitm3	interferon induced transmembrane protein 3	0.021
Dlx5	distal-less homeobox 5	0.021
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.019
Hoxb13	homeobox B13	0.019
Spink3	serine peptidase inhibitor, Kazal type 3	0.018
Zfp185	zinc finger protein 185	0.018
Pf4	platelet factor 4	0.018
Ret	ret proto-oncogene	0.017
Tcf21	transcription factor 21	0.016
Hoxd4	homeobox D4	0.016
Hand2	heart and neural crest derivatives expressed transcript 2	0.016
Spry4	sprouty homolog 4 (Drosophila)	0.016
Gli2	GLI-Kruppel family member GLI2	0.016
Mc1r	melanocortin 1 receptor	0.016
Emx2	empty spiracles homolog 2 (Drosophila)	0.015
Foxa2	forkhead box A2	0.015
Mybph	myosin binding protein H	0.015
Krt71	keratin 71	0.015
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.015
Sp6	trans-acting transcription factor 6	0.015
Wnt5a	wingless-related MMTV integration site 5A	0.014
Hoxd8	homeobox D8	0.014
Msx2	homeobox, msh-like 2	0.014
Phlda2	pleckstrin homology-like domain, family A, member 2	0.014
Fxyd3	FXYD domain-containing ion transport regulator 3	0.014
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.014
Hes1	hairy and enhancer of split 1 (Drosophila)	0.014
Krt14	keratin 14	0.013
Epha2	Eph receptor A2	0.013
Lef1	lymphoid enhancer binding factor 1	0.013
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.013
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.013
Ntn1	netrin 1	0.013
S100a14	S100 calcium binding protein A14	0.013
Sall4	sal-like 4 (Drosophila)	0.013
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.013
Col17a1	collagen, type XVII, alpha 1	0.013
Crabp1	cellular retinoic acid binding protein I	0.012
Esrp2	epithelial splicing regulatory protein 2	0.012
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.012
Col9a2	collagen, type IX, alpha 2	0.012
Krt31	keratin 31	0.012
Hoxd10	homeobox D10	0.012
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.011
Hand1	heart and neural crest derivatives expressed transcript 1	0.011
Col4a4	collagen, type IV, alpha 4	0.011
Hhat	hedgehog acyltransferase	0.011
Crabp2	cellular retinoic acid binding protein II	0.011
Ibsp	integrin binding sialoprotein	0.011
Efna2	ephrin A2	0.011
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.011
Agtr2	angiotensin II receptor, type 2	0.011
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.011
Trim10	tripartite motif-containing 10	0.011
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
Tcfap2b	transcription factor AP-2 beta	0.011
Itga3	integrin alpha 3	0.011
Eda	ectodysplasin-A	0.011
Tcf15	transcription factor 15	0.011
Foxc2	forkhead box C2	0.011
Krt5	keratin 5	0.010