IMP
Process View
vascular endothelial growth factor signaling pathway
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "vascular endothelial growth factor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Kdr | kinase insert domain protein receptor | 0.983 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.982 | Human Mouse | |
| Vegfa | vascular endothelial growth factor A | 0.908 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.720 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.470 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.460 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.438 | ||
| Cdh5 | cadherin 5 | 0.292 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.263 | ||
| Plxnd1 | plexin D1 | 0.188 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.177 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.165 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.150 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.128 | ||
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.093 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.092 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.078 | ||
| Meox2 | mesenchyme homeobox 2 | 0.075 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.075 | Human Mouse | |
| Sema3f | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.068 | ||
| Nrp1 | neuropilin 1 | 0.065 | ||
| Eng | endoglin | 0.060 | ||
| Tek | endothelial-specific receptor tyrosine kinase | 0.060 | ||
| Kitl | kit ligand | 0.056 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.048 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.038 | ||
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.036 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.035 | ||
| Pdgfa | platelet derived growth factor, alpha | 0.035 | Mouse | |
| Ece1 | endothelin converting enzyme 1 | 0.034 | ||
| Sox18 | SRY-box containing gene 18 | 0.033 | ||
| Podxl | podocalyxin-like | 0.033 | ||
| Thbd | thrombomodulin | 0.033 | ||
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.031 | ||
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.031 | ||
| Ldb2 | LIM domain binding 2 | 0.031 | ||
| Lamb1 | laminin B1 | 0.028 | ||
| Cd151 | CD151 antigen | 0.027 | ||
| Lamb2 | laminin, beta 2 | 0.027 | ||
| P4ha2 | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide | 0.026 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.026 | Mouse | |
| Esam | endothelial cell-specific adhesion molecule | 0.026 | ||
| Gaa | glucosidase, alpha, acid | 0.025 | ||
| Acvr1 | activin A receptor, type 1 | 0.025 | ||
| Tmem204 | transmembrane protein 204 | 0.024 | ||
| She | src homology 2 domain-containing transforming protein E | 0.024 | ||
| Cryab | crystallin, alpha B | 0.024 | ||
| Tinagl1 | tubulointerstitial nephritis antigen-like 1 | 0.023 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.023 | ||
| Large | like-glycosyltransferase | 0.023 | ||
| Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.022 | ||
| Sox7 | SRY-box containing gene 7 | 0.022 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.020 | ||
| Rbpms | RNA binding protein gene with multiple splicing | 0.020 | ||
| Ednrb | endothelin receptor type B | 0.019 | ||
| Wwc2 | WW, C2 and coiled-coil domain containing 2 | 0.019 | ||
| Apbb2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.019 | ||
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.018 | ||
| Itga3 | integrin alpha 3 | 0.018 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.016 | ||
| Src | Rous sarcoma oncogene | 0.016 | ||
| Col4a2 | collagen, type IV, alpha 2 | 0.016 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.016 | ||
| Lama4 | laminin, alpha 4 | 0.015 | ||
| Icam2 | intercellular adhesion molecule 2 | 0.015 | ||
| Fmnl3 | formin-like 3 | 0.015 | ||
| Vamp2 | vesicle-associated membrane protein 2 | 0.015 | ||
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.015 | ||
| Fbln1 | fibulin 1 | 0.015 | ||
| Pvr | poliovirus receptor | 0.014 | ||
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.014 | ||
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.014 | ||
| Plxna1 | plexin A1 | 0.014 | ||
| Emp2 | epithelial membrane protein 2 | 0.013 | ||
| Emcn | endomucin | 0.013 | ||
| Ptprg | protein tyrosine phosphatase, receptor type, G | 0.013 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.013 | ||
| Wwtr1 | WW domain containing transcription regulator 1 | 0.012 | ||
| Fli1 | Friend leukemia integration 1 | 0.012 | ||
| Tspan9 | tetraspanin 9 | 0.012 | ||
| Bmp6 | bone morphogenetic protein 6 | 0.011 | ||
| Hbegf | heparin-binding EGF-like growth factor | 0.011 | ||
| Mitf | microphthalmia-associated transcription factor | 0.011 | ||
| Ramp2 | receptor (calcitonin) activity modifying protein 2 | 0.011 | ||
| Cd97 | CD97 antigen | 0.011 | ||
| Aplnr | apelin receptor | 0.011 | ||
| Id1 | inhibitor of DNA binding 1 | 0.011 | ||
| Cldn5 | claudin 5 | 0.011 | ||
| Dab2 | disabled homolog 2 (Drosophila) | 0.011 | ||
| Rasip1 | Ras interacting protein 1 | 0.011 | ||
| Hlx | H2.0-like homeobox | 0.011 | ||
| Tspan12 | tetraspanin 12 | 0.011 | Mouse | |
| Rab10 | RAB10, member RAS oncogene family | 0.011 | ||
| Ptprm | protein tyrosine phosphatase, receptor type, M | 0.010 | ||
| Reck | reversion-inducing-cysteine-rich protein with kazal motifs | 0.010 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.010 |