IMP
Process View
posttranslational protein targeting to membrane
The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "posttranslational protein targeting to membrane"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Hsp90b1 | heat shock protein 90, beta (Grp94), member 1 | 0.355 | ||
| P4hb | prolyl 4-hydroxylase, beta polypeptide | 0.181 | ||
| Pdia3 | protein disulfide isomerase associated 3 | 0.150 | ||
| Surf4 | surfeit gene 4 | 0.097 | ||
| Bdnf | brain derived neurotrophic factor | 0.097 | ||
| Dnajb11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.096 | ||
| Prkcsh | protein kinase C substrate 80K-H | 0.094 | ||
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.076 | ||
| Pdia6 | protein disulfide isomerase associated 6 | 0.074 | ||
| Canx | calnexin | 0.071 | ||
| Tram1 | translocating chain-associating membrane protein 1 | 0.068 | ||
| Magt1 | magnesium transporter 1 | 0.063 | ||
| Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.061 | ||
| Gorasp2 | golgi reassembly stacking protein 2 | 0.053 | ||
| Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.048 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.046 | ||
| Dnajc3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.045 | ||
| Clasp1 | CLIP associating protein 1 | 0.041 | ||
| Spna2 | spectrin alpha 2 | 0.036 | ||
| Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.036 | ||
| Ssr3 | signal sequence receptor, gamma | 0.036 | ||
| Arcn1 | archain 1 | 0.036 | ||
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.035 | ||
| Spnb2 | spectrin beta 2 | 0.034 | ||
| Uso1 | USO1 homolog, vesicle docking protein (yeast) | 0.034 | ||
| Slc35b1 | solute carrier family 35, member B1 | 0.031 | ||
| Ssr1 | signal sequence receptor, alpha | 0.031 | ||
| Lrrc59 | leucine rich repeat containing 59 | 0.029 | ||
| Creld2 | cysteine-rich with EGF-like domains 2 | 0.028 | ||
| Rrbp1 | ribosome binding protein 1 | 0.028 | ||
| Slc39a7 | solute carrier family 39 (zinc transporter), member 7 | 0.027 | ||
| Hspa5 | heat shock protein 5 | 0.027 | Yeast | |
| Sel1l | sel-1 suppressor of lin-12-like (C. elegans) | 0.027 | ||
| Sec31a | Sec31 homolog A (S. cerevisiae) | 0.027 | ||
| Sec63 | SEC63-like (S. cerevisiae) | 0.026 | ||
| Ntf3 | neurotrophin 3 | 0.023 | ||
| Fastk | Fas-activated serine/threonine kinase | 0.023 | ||
| D730040F13Rik | RIKEN cDNA D730040F13 gene | 0.022 | ||
| Sec23b | SEC23B (S. cerevisiae) | 0.022 | ||
| Hspa13 | heat shock protein 70 family, member 13 | 0.022 | ||
| Dync1h1 | dynein cytoplasmic 1 heavy chain 1 | 0.022 | ||
| Nrg1 | neuregulin 1 | 0.022 | ||
| Xbp1 | X-box binding protein 1 | 0.020 | ||
| Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.019 | ||
| Nomo1 | nodal modulator 1 | 0.019 | ||
| Txndc5 | thioredoxin domain containing 5 | 0.019 | ||
| Ttc3 | tetratricopeptide repeat domain 3 | 0.019 | ||
| Copg | coatomer protein complex, subunit gamma | 0.019 | ||
| Kif1b | kinesin family member 1B | 0.019 | ||
| Dctn1 | dynactin 1 | 0.019 | ||
| Invs | inversin | 0.018 | ||
| Uba5 | ubiquitin-like modifier activating enzyme 5 | 0.018 | ||
| Lmna | lamin A | 0.018 | ||
| Kpna3 | karyopherin (importin) alpha 3 | 0.017 | ||
| Calu | calumenin | 0.017 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.016 | ||
| Usp48 | ubiquitin specific peptidase 48 | 0.015 | ||
| Ddost | dolichyl-di-phosphooligosaccharide-protein glycotransferase | 0.015 | ||
| Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 0.015 | ||
| Rpn2 | ribophorin II | 0.015 | ||
| Tnrc6a | trinucleotide repeat containing 6a | 0.014 | ||
| Hgs | HGF-regulated tyrosine kinase substrate | 0.014 | ||
| Gnl1 | guanine nucleotide binding protein-like 1 | 0.014 | ||
| Cdc42bpa | CDC42 binding protein kinase alpha | 0.014 | ||
| Dag1 | dystroglycan 1 | 0.013 | ||
| Dlg1 | discs, large homolog 1 (Drosophila) | 0.013 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.013 | ||
| Ncln | nicalin homolog (zebrafish) | 0.013 | ||
| Clasp2 | CLIP associating protein 2 | 0.013 | ||
| Epn1 | epsin 1 | 0.013 | ||
| Clptm1 | cleft lip and palate associated transmembrane protein 1 | 0.012 | ||
| Lamc1 | laminin, gamma 1 | 0.012 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.012 | ||
| Git1 | G protein-coupled receptor kinase-interactor 1 | 0.012 | ||
| Glg1 | golgi apparatus protein 1 | 0.012 | ||
| Copb2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.012 | ||
| Cask | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.012 | ||
| Atp2a2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.012 | ||
| Rpn1 | ribophorin I | 0.012 | ||
| Lman1 | lectin, mannose-binding, 1 | 0.012 | ||
| Hyou1 | hypoxia up-regulated 1 | 0.011 | ||
| Hdlbp | high density lipoprotein (HDL) binding protein | 0.011 | ||
| Mlec | malectin | 0.011 | ||
| Ahi1 | Abelson helper integration site 1 | 0.011 | ||
| Dscaml1 | Down syndrome cell adhesion molecule-like 1 | 0.011 | ||
| ORF61 | open reading frame 61 | 0.011 | ||
| Spcs3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.011 | ||
| Ubr4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.011 | ||
| Sdf2l1 | stromal cell-derived factor 2-like 1 | 0.011 | ||
| Pex14 | peroxisomal biogenesis factor 14 | 0.011 | ||
| Atp9a | ATPase, class II, type 9A | 0.011 | ||
| Lpp | LIM domain containing preferred translocation partner in lipoma | 0.011 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.011 | ||
| Csnk1g2 | casein kinase 1, gamma 2 | 0.011 | ||
| Erp44 | endoplasmic reticulum protein 44 | 0.010 | ||
| Mtap4 | microtubule-associated protein 4 | 0.010 | ||
| Pdia4 | protein disulfide isomerase associated 4 | 0.010 | ||
| Slc27a4 | solute carrier family 27 (fatty acid transporter), member 4 | 0.010 |