IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

negative regulation of type i hypersensitivity

GO:0001811

Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of type i hypersensitivity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of type i hypersensitivity" (in gray)

Name	Description	Probability	Func Analog Organism
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.714
Lyz2	lysozyme 2	0.437
C1qb	complement component 1, q subcomponent, beta polypeptide	0.342
Tyrobp	TYRO protein tyrosine kinase binding protein	0.315
Ptprc	protein tyrosine phosphatase, receptor type, C	0.221
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.177
Aif1	allograft inflammatory factor 1	0.171
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.160
C1qc	complement component 1, q subcomponent, C chain	0.150
Ly86	lymphocyte antigen 86	0.132
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.131
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.119
Csf1r	colony stimulating factor 1 receptor	0.102
Fcgr1	Fc receptor, IgG, high affinity I	0.087	Mouse
Clec4n	C-type lectin domain family 4, member n	0.087
Msr1	macrophage scavenger receptor 1	0.076
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.073
C3ar1	complement component 3a receptor 1	0.073
Ccr1	chemokine (C-C motif) receptor 1	0.064
Cd19	CD19 antigen	0.063
AF251705	cDNA sequence AF251705	0.057
Ccl6	chemokine (C-C motif) ligand 6	0.050
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.049
Cd180	CD180 antigen	0.049
Sfpi1	SFFV proviral integration 1	0.048
Ifitm6	interferon induced transmembrane protein 6	0.047
Ccl9	chemokine (C-C motif) ligand 9	0.045
Cybb	cytochrome b-245, beta polypeptide	0.042
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.040
Cd22	CD22 antigen	0.040
Hck	hemopoietic cell kinase	0.036
Cd52	CD52 antigen	0.035
Cr2	complement receptor 2	0.033
Btk	Bruton agammaglobulinemia tyrosine kinase	0.032
Ctss	cathepsin S	0.031
Clec7a	C-type lectin domain family 7, member a	0.030
Mrc1	mannose receptor, C type 1	0.028
Cd68	CD68 antigen	0.027
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.027
Akap4	A kinase (PRKA) anchor protein 4	0.026
Inpp5d	inositol polyphosphate-5-phosphatase D	0.025
Fasl	Fas ligand (TNF superfamily, member 6)	0.025
Cxcr2	chemokine (C-X-C motif) receptor 2	0.024
Lyz1	lysozyme 1	0.024
Mpeg1	macrophage expressed gene 1	0.023
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.023
Clec4a2	C-type lectin domain family 4, member a2	0.022
Fpr2	formyl peptide receptor 2	0.022
Cd86	CD86 antigen	0.022
Cd96	CD96 antigen	0.021
Fcgr4	Fc receptor, IgG, low affinity IV	0.021
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.021
Clec4d	C-type lectin domain family 4, member d	0.021
Il1b	interleukin 1 beta	0.020
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.020
Cd14	CD14 antigen	0.019
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.019
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.019
Lair1	leukocyte-associated Ig-like receptor 1	0.018
Tlr7	toll-like receptor 7	0.017
Ifng	interferon gamma	0.017
Pld4	phospholipase D family, member 4	0.017
Sell	selectin, lymphocyte	0.017
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.017
Ncf1	neutrophil cytosolic factor 1	0.017
Folr2	folate receptor 2 (fetal)	0.016
Il10	interleukin 10	0.016
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.015
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.015
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.015
Fcgr3	Fc receptor, IgG, low affinity III	0.014	Mouse
Ccr5	chemokine (C-C motif) receptor 5	0.014
Apoe	apolipoprotein E	0.014
Ncr1	natural cytotoxicity triggering receptor 1	0.014
Itgb2	integrin beta 2	0.013
Ccr2	chemokine (C-C motif) receptor 2	0.013
Ccl12	chemokine (C-C motif) ligand 12	0.013
Selp	selectin, platelet	0.013
Ccr3	chemokine (C-C motif) receptor 3	0.013
Gcet2	germinal center expressed transcript 2	0.013
C3	complement component 3	0.013
BC013712	cDNA sequence BC013712	0.012
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.012
Cxcl13	chemokine (C-X-C motif) ligand 13	0.012
Cd53	CD53 antigen	0.012
Pilra	paired immunoglobin-like type 2 receptor alpha	0.012
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.012
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.012
Pbsn	probasin	0.011
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.011
Ncf4	neutrophil cytosolic factor 4	0.011
Ccl8	chemokine (C-C motif) ligand 8	0.011
Ifngr1	interferon gamma receptor 1	0.011
Cfp	complement factor properdin	0.011
Trem3	triggering receptor expressed on myeloid cells 3	0.011
Unc93b1	unc-93 homolog B1 (C. elegans)	0.010
Prg2	proteoglycan 2, bone marrow	0.010
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.010
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.010
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.010
Fpr1	formyl peptide receptor 1	0.010
Ccr7	chemokine (C-C motif) receptor 7	0.010