IMP

Process View

Mus musculus

1 genes annotated in mouse

oxidative demethylation

The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "oxidative demethylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "oxidative demethylation" (in gray)

Name	Description	Probability	Func Analog Organism
Otc	ornithine transcarbamylase	0.995
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.993	Human Rat
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.977	Human
Cps1	carbamoyl-phosphate synthetase 1	0.952
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.921
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.908
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.883
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.819
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.776	Human Rat
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.753
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.751
F9	coagulation factor IX	0.747
Sult1d1	sulfotransferase family 1D, member 1	0.739
Ces2a	carboxylesterase 2A	0.692
Sult1b1	sulfotransferase family 1B, member 1	0.651
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.650
Akr1c6	aldo-keto reductase family 1, member C6	0.629
Aldob	aldolase B, fructose-bisphosphate	0.620
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.612
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.558
Rdh7	retinol dehydrogenase 7	0.550
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.481
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.476
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.449
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.440
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.432
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.427
Aadac	arylacetamide deacetylase (esterase)	0.419
Crp	C-reactive protein, pentraxin-related	0.398
Hrg	histidine-rich glycoprotein	0.398
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.382
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.380
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.354
Mbl2	mannose-binding lectin (protein C) 2	0.351
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.332	Human
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.326
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.314
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.303
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.295
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.281
G6pc	glucose-6-phosphatase, catalytic	0.266
Ces1g	carboxylesterase 1G	0.263
Cfhr1	complement factor H-related 1	0.256
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.249
Tdo2	tryptophan 2,3-dioxygenase	0.247
F13b	coagulation factor XIII, beta subunit	0.230
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.227
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.227
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.224	Human Rat
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.212
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.204
Cyp3a41b	cytochrome P450, family 3, subfamily a, polypeptide 41B	0.199	Human Rat
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.196
Ces1c	carboxylesterase 1C	0.194
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.183
Fabp2	fatty acid binding protein 2, intestinal	0.177
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.164	Human
Uox	urate oxidase	0.158
Mug2	murinoglobulin 2	0.157
Ces3a	carboxylesterase 3A	0.152
Alb	albumin	0.150
Ugt2b35	UDP glucuronosyltransferase 2 family, polypeptide B35	0.145
Cml2	camello-like 2	0.140
Sval1	seminal vesicle antigen-like 1	0.139
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.139
Mug1	murinoglobulin 1	0.136
Fabp1	fatty acid binding protein 1, liver	0.132
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.132
Cyp2c65	cytochrome P450, family 2, subfamily c, polypeptide 65	0.131	Human
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.125	Human
Gc	group specific component	0.124
Bhmt	betaine-homocysteine methyltransferase	0.124
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.122
Tex12	testis expressed gene 12	0.117
Azgp1	alpha-2-glycoprotein 1, zinc	0.113
Akr1d1	aldo-keto reductase family 1, member D1	0.113
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.112
Apoh	apolipoprotein H	0.109
Acot12	acyl-CoA thioesterase 12	0.105
Fbp1	fructose bisphosphatase 1	0.104
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.103
BC089597	cDNA sequence BC089597	0.102
Clec2h	C-type lectin domain family 2, member h	0.099
Mup3	major urinary protein 3	0.098
Hgd	homogentisate 1, 2-dioxygenase	0.098
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.096
Apob	apolipoprotein B	0.094
Glyat	glycine-N-acyltransferase	0.092
Vmn1r45	vomeronasal 1 receptor 45	0.092
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.091
Fmo5	flavin containing monooxygenase 5	0.089
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.086
Hsd17b13	hydroxysteroid (17-beta) dehydrogenase 13	0.086
D630002G06Rik	RIKEN cDNA D630002G06 gene	0.085
Vmn1r56	vomeronasal 1 receptor 56	0.084
Gm4788	predicted gene 4788	0.080
Apoc3	apolipoprotein C-III	0.079
AB056442	cDNA sequence AB056442	0.079
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.075
Pah	phenylalanine hydroxylase	0.074
Cfhr2	complement factor H-related 2	0.073
Tmem59	transmembrane protein 59	0.071
Klkb1	kallikrein B, plasma 1	0.069
Hao2	hydroxyacid oxidase 2	0.069
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.067
Hao1	hydroxyacid oxidase 1, liver	0.067
Leap2	liver-expressed antimicrobial peptide 2	0.063
Olfr749	olfactory receptor 749	0.061
Cml5	camello-like 5	0.060
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.058
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.056
2310057N15Rik	RIKEN cDNA 2310057N15 gene	0.055
Tas2r105	taste receptor, type 2, member 105	0.055
Vmn1r47	vomeronasal 1 receptor 47	0.054
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.053
Tm4sf4	transmembrane 4 superfamily member 4	0.053
Iyd	iodotyrosine deiodinase	0.052
Afm	afamin	0.052
Csl	citrate synthase like	0.051
Cyp4f14	cytochrome P450, family 4, subfamily f, polypeptide 14	0.050
Mup5	major urinary protein 5	0.050
Upp2	uridine phosphorylase 2	0.048
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.048
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.048
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.048
Mup19	major urinary protein 19	0.048
Anxa13	annexin A13	0.048
Ces2e	carboxylesterase 2E	0.047
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.047
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.046
Dio1	deiodinase, iodothyronine, type I	0.046
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.045
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.044	Human
4930542N07Rik	RIKEN cDNA 4930542N07 gene	0.044
Rgn	regucalcin	0.044
2810007J24Rik	RIKEN cDNA 2810007J24 gene	0.043
Galm	galactose mutarotase	0.043
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.042
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.042
Kynu	kynureninase (L-kynurenine hydrolase)	0.040
C4bp	complement component 4 binding protein	0.040
Gsta3	glutathione S-transferase, alpha 3	0.039
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.039
Hamp	hepcidin antimicrobial peptide	0.037
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.037
Bche	butyrylcholinesterase	0.036
Apcs	serum amyloid P-component	0.036
Sucnr1	succinate receptor 1	0.036
Nat1	N-acetyl transferase 1	0.036
Cdh17	cadherin 17	0.036
Vsig4	V-set and immunoglobulin domain containing 4	0.036
Sult3a1	sulfotransferase family 3A, member 1	0.035
Cdhr5	cadherin-related family member 5	0.034
Lipc	lipase, hepatic	0.034
Tat	tyrosine aminotransferase	0.034
Ugt2b37	UDP glucuronosyltransferase 2 family, polypeptide B37	0.034
9130016M20Rik	RIKEN cDNA 9130016M20 gene	0.033
Tmprss15	transmembrane protease, serine 15	0.032
Prl7a1	prolactin family 7, subfamily a, member 1	0.032
Prlr	prolactin receptor	0.032
Cfi	complement component factor i	0.032
Defb1	defensin beta 1	0.032
Keg1	kidney expressed gene 1	0.032
Vmn1r58	vomeronasal 1 receptor 58	0.032
Mia2	melanoma inhibitory activity 2	0.032
Acot4	acyl-CoA thioesterase 4	0.031
Akr1c20	aldo-keto reductase family 1, member C20	0.031
Slc15a1	solute carrier family 15 (oligopeptide transporter), member 1	0.030
Dnajb7	DnaJ (Hsp40) homolog, subfamily B, member 7	0.030
Angptl3	angiopoietin-like 3	0.030
Slc10a2	solute carrier family 10, member 2	0.030
Slco1a6	solute carrier organic anion transporter family, member 1a6	0.030
Slc17a2	solute carrier family 17 (sodium phosphate), member 2	0.030
Tm4sf20	transmembrane 4 L six family member 20	0.030
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.029
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.029
Gys2	glycogen synthase 2	0.027
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.026
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.026
Prl2c1	Prolactin family 2, subfamily c, member 1	0.026
Mettl7b	methyltransferase like 7B	0.025
Ugt2b38	UDP glucuronosyltransferase 2 family, polypeptide B38	0.025
Tmed11	transmembrane emp24 protein transport domain containing	0.025
Agxt	alanine-glyoxylate aminotransferase	0.024
Daf2	decay accelerating factor 2	0.024
Klk1b4	kallikrein 1-related pepidase b4	0.023
Sgk2	serum/glucocorticoid regulated kinase 2	0.023
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.023
Art2b	ADP-ribosyltransferase 2b	0.023
Fga	fibrinogen alpha chain	0.022
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.022
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.022
Dpys	dihydropyrimidinase	0.022
Bhmt2	betaine-homocysteine methyltransferase 2	0.021
Acsm1	acyl-CoA synthetase medium-chain family member 1	0.021
Mup4	major urinary protein 4	0.021
Rdh9	retinol dehydrogenase 9	0.021
Inmt	indolethylamine N-methyltransferase	0.021
Vmn1r29	vomeronasal 1 receptor 29	0.021
Ddc	dopa decarboxylase	0.021
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.020
2610015P09Rik	RIKEN cDNA 2610015P09 gene	0.020
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.020
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.020
Apon	apolipoprotein N	0.020
Bco2	beta-carotene oxygenase 2	0.020
Abca6	ATP-binding cassette, sub-family A (ABC1), member 6	0.020
Defa15	defensin, alpha, 15	0.020
Pemt	phosphatidylethanolamine N-methyltransferase	0.020
Cyp3a59	cytochrome P450, subfamily 3A, polypeptide 59	0.019	Human
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.019
Ambp	alpha 1 microglobulin/bikunin	0.019
Ces1e	carboxylesterase 1E	0.019
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.019
Acnat2	acyl-coenzyme A amino acid N-acyltransferase 2	0.019
Vmn1r172	vomeronasal 1 receptor 172	0.019
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.019
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.019
Vmn1r53	vomeronasal 1 receptor 53	0.019
Cyp2c44	cytochrome P450, family 2, subfamily c, polypeptide 44	0.019
Slc26a3	solute carrier family 26, member 3	0.018
Adam26a	a disintegrin and metallopeptidase domain 26A (testase 3)	0.018
Reg1	regenerating islet-derived 1	0.018
Lrrc67	leucine rich repeat containing 67	0.017
Ndrg2	N-myc downstream regulated gene 2	0.017
Gstm3	glutathione S-transferase, mu 3	0.017
Rdh16	retinol dehydrogenase 16	0.017
Mmp1a	matrix metallopeptidase 1a (interstitial collagenase)	0.017
Nlrp6	NLR family, pyrin domain containing 6	0.017
Il21	interleukin 21	0.017
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.017
Psg23	pregnancy-specific glycoprotein 23	0.017
Pdzd9	PDZ domain containing 9	0.016
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.016
Cyp3a41a	cytochrome P450, family 3, subfamily a, polypeptide 41A	0.016	Human Rat
Vmn1r51	vomeronasal 1 receptor 51	0.016
Pon1	paraoxonase 1	0.016
Bphl	biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)	0.016
A1cf	APOBEC1 complementation factor	0.015
Kng1	kininogen 1	0.015
Mup10	major urinary protein 10	0.015
Magea5	melanoma antigen, family A, 5	0.015
C9	complement component 9	0.015
Aadat	aminoadipate aminotransferase	0.015
Abcg8	ATP-binding cassette, sub-family G (WHITE), member 8	0.015
Lce1c	late cornified envelope 1C	0.015
Dpyd	dihydropyrimidine dehydrogenase	0.015
Uqcrq	ubiquinol-cytochrome c reductase, complex III subunit VII	0.015
Arl14	ADP-ribosylation factor-like 14	0.015
Apol7a	apolipoprotein L 7a	0.015
Hnf4a	hepatic nuclear factor 4, alpha	0.015
Iigp1b	interferon inducible GTPase 1B	0.015
F2	coagulation factor II	0.015
Mgam	maltase-glucoamylase	0.015
Olfr67	olfactory receptor 67	0.015
Ces1f	carboxylesterase 1F	0.015
Sult1e1	sulfotransferase family 1E, member 1	0.015
Gstm6	glutathione S-transferase, mu 6	0.015
4930521A18Rik	RIKEN cDNA 4930521A18 gene	0.015
Pdcl2	phosducin-like 2	0.014
Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.014
Pipox	pipecolic acid oxidase	0.014
Spink3	serine peptidase inhibitor, Kazal type 3	0.014
Upb1	ureidopropionase, beta	0.014
Slc15a5	solute carrier family 15, member 5	0.014
Asah2	N-acylsphingosine amidohydrolase 2	0.014
Olfr69	olfactory receptor 69	0.014
Fmo4	flavin containing monooxygenase 4	0.014
Olfr68	olfactory receptor 68	0.013
Ces1d	carboxylesterase 1D	0.013
Psg28	pregnancy-specific glycoprotein 28	0.013
Apoc4	apolipoprotein C-IV	0.013
Tm6sf2	transmembrane 6 superfamily member 2	0.013
Gm13023	predicted gene 13023	0.013
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.013
H2-T3	histocompatibility 2, T region locus 3	0.013
Ttr	transthyretin	0.013
Tsku	tsukushin	0.013
Gzmn	granzyme N	0.013
Ces2b	carboxyesterase 2B	0.013
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.012
Soat2	sterol O-acyltransferase 2	0.012
Vmn1r30	vomeronasal 1 receptor 30	0.012
Lgals6	lectin, galactose binding, soluble 6	0.012
Ephx1	epoxide hydrolase 1, microsomal	0.012
Serpinb3b	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B	0.012
F11	coagulation factor XI	0.012
Serpinb9d	serine (or cysteine) peptidase inhibitor, clade B, member 9d	0.012
Prl5a1	prolactin family 5, subfamily a, member 1	0.012
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.012
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.012
Clca6	chloride channel calcium activated 6	0.012
Adam34	a disintegrin and metallopeptidase domain 34	0.012
Slc38a4	solute carrier family 38, member 4	0.012
1700016D06Rik	RIKEN cDNA 1700016D06 gene	0.012
Fetub	fetuin beta	0.012
Sec16b	SEC16 homolog B (S. cerevisiae)	0.012
Pigr	polymeric immunoglobulin receptor	0.012
LOC100048884	novel member of the major urinary protein (Mup) gene family	0.012
Defa24	defensin, alpha, 24	0.012
Akr1c13	aldo-keto reductase family 1, member C13	0.011
Agtr1a	angiotensin II receptor, type 1a	0.011
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.011
Zfp605	zinc finger protein 605	0.011
Akr1c12	aldo-keto reductase family 1, member C12	0.011
Vmn1r9	vomeronasal 1 receptor 9	0.011
Pklr	pyruvate kinase liver and red blood cell	0.011
Vmn1r11	vomeronasal 1 receptor 11	0.011
Akr1c19	aldo-keto reductase family 1, member C19	0.011
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.011
4930403N07Rik	RIKEN cDNA 4930403N07 gene	0.011
AI747448	expressed sequence AI747448	0.011
Snapc5	small nuclear RNA activating complex, polypeptide 5	0.011
Fgl1	fibrinogen-like protein 1	0.011
Gstm1	glutathione S-transferase, mu 1	0.011
Lrrc19	leucine rich repeat containing 19	0.011
2010106E10Rik	RIKEN cDNA 2010106E10 gene	0.011
Ahsg	alpha-2-HS-glycoprotein	0.011
Adh1	alcohol dehydrogenase 1 (class I)	0.011
Pcdhb14	protocadherin beta 14	0.010
Lce3a	late cornified envelope 3A	0.010
Apof	apolipoprotein F	0.010
Fgb	fibrinogen beta chain	0.010
Fbxw24	F-box and WD-40 domain protein 24	0.010
AA517545	expressed sequence AA517545	0.010
Krtap16-9	keratin associated protein 16-9	0.010
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.010
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.010
Zfp353	zinc finger protein 353	0.010
Aass	aminoadipate-semialdehyde synthase	0.010
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.010
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.010