IMP

Process View

Mus musculus

4 genes annotated in mouse

dopamine catabolic process

The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dopamine catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dopamine catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Th	tyrosine hydroxylase	0.455
Emx1	empty spiracles homolog 1 (Drosophila)	0.410
Unc79	unc-79 homolog (C. elegans)	0.400
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.376
Pick1	protein interacting with C kinase 1	0.338
Snca	synuclein, alpha	0.295
Drd2	dopamine receptor D2	0.218
Vav2	vav 2 oncogene	0.134
Tff1	trefoil factor 1	0.109
Lhx3	LIM homeobox protein 3	0.104
Dao	D-amino acid oxidase	0.088
Drd1a	dopamine receptor D1A	0.083
Gpr37l1	G protein-coupled receptor 37-like 1	0.074
Cplx1	complexin 1	0.068
Hcrt	hypocretin	0.060
Syt6	synaptotagmin VI	0.053
Adm	adrenomedullin	0.053
Mfn2	mitofusin 2	0.047
Cnr1	cannabinoid receptor 1 (brain)	0.046
Pparg	peroxisome proliferator activated receptor gamma	0.044
Irx6	Iroquois related homeobox 6 (Drosophila)	0.042
Olfr155	olfactory receptor 155	0.041
Rtbdn	retbindin	0.040
Ctrb1	chymotrypsinogen B1	0.040
Rit2	Ras-like without CAAX 2	0.036
Apoa5	apolipoprotein A-V	0.036
Srd5a2	steroid 5 alpha-reductase 2	0.035
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.033
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.033
Olfr71	olfactory receptor 71	0.032
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.030
Pvalb	parvalbumin	0.029
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.028
Defb2	defensin beta 2	0.027
Mid2	midline 2	0.026
Krt32	keratin 32	0.026
Sncb	synuclein, beta	0.025
Nptx1	neuronal pentraxin 1	0.025
Ppyr1	pancreatic polypeptide receptor 1	0.024
Htr3b	5-hydroxytryptamine (serotonin) receptor 3B	0.024
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.024
Myh14	myosin, heavy polypeptide 14	0.024
Mag	myelin-associated glycoprotein	0.023
Kap	kidney androgen regulated protein	0.023
Cyp2b19	cytochrome P450, family 2, subfamily b, polypeptide 19	0.022
Calb2	calbindin 2	0.022
Adra2b	adrenergic receptor, alpha 2b	0.022
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.021
Dpp6	dipeptidylpeptidase 6	0.021
Adora2b	adenosine A2b receptor	0.020
Col4a4	collagen, type IV, alpha 4	0.020
Adora2a	adenosine A2a receptor	0.020
Dag1	dystroglycan 1	0.019
Gzmm	granzyme M (lymphocyte met-ase 1)	0.019
Inpp5j	inositol polyphosphate 5-phosphatase J	0.019
Vsx1	visual system homeobox 1 homolog (zebrafish)	0.019
Irs2	insulin receptor substrate 2	0.018
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.018
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.018
Ntsr2	neurotensin receptor 2	0.018
Miox	myo-inositol oxygenase	0.017
Edn2	endothelin 2	0.017
Oxt	oxytocin	0.017
Sspo	SCO-spondin	0.017
Epb4.9	erythrocyte protein band 4.9	0.017
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.017
Krtap5-1	keratin associated protein 5-1	0.017
Ptgfrn	prostaglandin F2 receptor negative regulator	0.016
Ank1	ankyrin 1, erythroid	0.016
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.016
Cldn15	claudin 15	0.016
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.016
Mogat2	monoacylglycerol O-acyltransferase 2	0.015
Pla2g12b	phospholipase A2, group XIIB	0.015
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.015
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.015
Vil1	villin 1	0.015
Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.015	Mouse
Mybpc3	myosin binding protein C, cardiac	0.015
Oprm1	opioid receptor, mu 1	0.015
Cdc42bpa	CDC42 binding protein kinase alpha	0.014
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.014
G6pc	glucose-6-phosphatase, catalytic	0.014
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.014
Adcy1	adenylate cyclase 1	0.014
Opn4	opsin 4 (melanopsin)	0.014
Ankrd33	ankyrin repeat domain 33	0.014
Grm2	glutamate receptor, metabotropic 2	0.014
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.014
App	amyloid beta (A4) precursor protein	0.013
Chrnb3	cholinergic receptor, nicotinic, beta polypeptide 3	0.013
Atxn1	ataxin 1	0.013
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.013
C1ql1	complement component 1, q subcomponent-like 1	0.013
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.013
Barhl1	BarH-like 1 (Drosophila)	0.013
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.013
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.013
Cntn2	contactin 2	0.013
Gata1	GATA binding protein 1	0.013
Sftpb	surfactant associated protein B	0.013
Lhx4	LIM homeobox protein 4	0.013
Vipr2	vasoactive intestinal peptide receptor 2	0.012
Sst	somatostatin	0.012
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.012
Cort	cortistatin	0.012
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.012
Hand1	heart and neural crest derivatives expressed transcript 1	0.012
Prph2	peripherin 2	0.012
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.012
A530016L24Rik	RIKEN cDNA A530016L24 gene	0.012
Bhlhe40	basic helix-loop-helix family, member e40	0.012
Arx	aristaless related homeobox	0.012
Hyal3	hyaluronoglucosaminidase 3	0.012
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.011
Pet2	plasmacytoma expressed transcript 2	0.011
Magel2	melanoma antigen, family L, 2	0.011
Gsx1	GS homeobox 1	0.011
Hipk2	homeodomain interacting protein kinase 2	0.011
Slc22a13	solute carrier family 22 (organic cation transporter), member 13	0.011
6330512M04Rik	RIKEN cDNA 6330512M04 gene	0.011
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.011
Col4a3	collagen, type IV, alpha 3	0.011
Gal	galanin	0.011
Rbp3	retinol binding protein 3, interstitial	0.011
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.011
Rax	retina and anterior neural fold homeobox	0.011
Coro1c	coronin, actin binding protein 1C	0.011
Itga3	integrin alpha 3	0.011
Adcy2	adenylate cyclase 2	0.011
Rac1	RAS-related C3 botulinum substrate 1	0.011
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.011	Mouse
Sox10	SRY-box containing gene 10	0.011
Sfrp5	secreted frizzled-related sequence protein 5	0.011
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.010
Ucn	urocortin	0.010
Gjd2	gap junction protein, delta 2	0.010
Hes5	hairy and enhancer of split 5 (Drosophila)	0.010
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.010
Calcb	calcitonin-related polypeptide, beta	0.010
Ndp	Norrie disease (pseudoglioma) (human)	0.010
Nln	neurolysin (metallopeptidase M3 family)	0.010
Cltb	clathrin, light polypeptide (Lcb)	0.010
Tpp1	tripeptidyl peptidase I	0.010
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.010
Grin2c	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	0.010
Angpt4	angiopoietin 4	0.010
Aatk	apoptosis-associated tyrosine kinase	0.010