Process View
0 genes annotated in mouse
DOID:680
A neurodegenerative disease that has material basis in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.

In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Psen1 | presenilin 1 | 0.958 | Human | |
| Prnp | prion protein | 0.629 | ||
| Ncstn | nicastrin | 0.550 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.499 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.248 | ||
| Aph1a | anterior pharynx defective 1a homolog (C. elegans) | 0.202 | ||
| App | amyloid beta (A4) precursor protein | 0.190 | Human | |
| Aplp2 | amyloid beta (A4) precursor-like protein 2 | 0.140 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.099 | ||
| Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.077 | ||
| Psen2 | presenilin 2 | 0.075 | Human | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.067 | ||
| Numb | numb gene homolog (Drosophila) | 0.058 | ||
| Erlin2 | ER lipid raft associated 2 | 0.055 | ||
| Psap | prosaposin | 0.049 | ||
| Itm2b | integral membrane protein 2B | 0.043 | ||
| Clstn1 | calsyntenin 1 | 0.043 | ||
| Npc1 | Niemann Pick type C1 | 0.038 | ||
| Calr | calreticulin | 0.031 | ||
| Ctsd | cathepsin D | 0.027 | ||
| Ldlr | low density lipoprotein receptor | 0.023 | ||
| Cp | ceruloplasmin | 0.023 | ||
| Nucb1 | nucleobindin 1 | 0.022 | ||
| Dlg1 | discs, large homolog 1 (Drosophila) | 0.019 | ||
| Psenen | presenilin enhancer 2 homolog (C. elegans) | 0.018 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.018 | ||
| 0610031J06Rik | RIKEN cDNA 0610031J06 gene | 0.018 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.017 | ||
| Cav1 | caveolin 1, caveolae protein | 0.016 | ||
| Plat | plasminogen activator, tissue | 0.016 | ||
| Itm2c | integral membrane protein 2C | 0.015 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.015 | ||
| Wls | wntless homolog (Drosophila) | 0.015 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta 2 | 0.013 | ||
| Sparcl1 | SPARC-like 1 | 0.013 | ||
| Cpd | carboxypeptidase D | 0.013 | ||
| Atp6v0d1 | ATPase, H+ transporting, lysosomal V0 subunit D1 | 0.012 | ||
| Lyz2 | lysozyme 2 | 0.012 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.012 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.011 | ||
| Mapk3 | mitogen-activated protein kinase 3 | 0.011 | ||
| Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A | 0.011 | ||
| Mt1 | metallothionein 1 | 0.011 | ||
| Ergic3 | ERGIC and golgi 3 | 0.011 | ||
| Atp6v0b | ATPase, H+ transporting, lysosomal V0 subunit B | 0.010 | ||
| Abhd12 | abhydrolase domain containing 12 | 0.010 |