IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

iron sulfur cluster assembly

GO:0016226

The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "iron sulfur cluster assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "iron sulfur cluster assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Sdhaf2	succinate dehydrogenase complex assembly factor 2	0.750
Mrps23	mitochondrial ribosomal protein S23	0.508
Hmbs	hydroxymethylbilane synthase	0.454
Nubp1	nucleotide binding protein 1	0.443	Human Yeast
Dus1l	dihydrouridine synthase 1-like (S. cerevisiae)	0.420
Nubp2	nucleotide binding protein 2	0.398	Yeast
Ptcd2	pentatricopeptide repeat domain 2	0.383
Atpaf2	ATP synthase mitochondrial F1 complex assembly factor 2	0.378
Mrpl16	mitochondrial ribosomal protein L16	0.356
Ddx41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	0.344
Mrps18b	mitochondrial ribosomal protein S18B	0.333
Parl	presenilin associated, rhomboid-like	0.327
Mrps7	mitchondrial ribosomal protein S7	0.321
Psmg1	proteasome (prosome, macropain) assembly chaperone 1	0.301
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.300
Exosc5	exosome component 5	0.282
Nudt1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	0.255
Mrpl37	mitochondrial ribosomal protein L37	0.252
Ddx56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.240
2610027L16Rik	RIKEN cDNA 2610027L16 gene	0.240
Vps25	vacuolar protein sorting 25 (yeast)	0.215
Grpel1	GrpE-like 1, mitochondrial	0.206
Wdr46	WD repeat domain 46	0.195
Mrpl40	mitochondrial ribosomal protein L40	0.186
Ciao1	cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)	0.186	Human Yeast
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.183
Pdhb	pyruvate dehydrogenase (lipoamide) beta	0.172
Uqcc	ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast)	0.159
Immp1l	IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)	0.159
Polr3c	polymerase (RNA) III (DNA directed) polypeptide C	0.150
Mrpl2	mitochondrial ribosomal protein L2	0.148
Lsm4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.146
Imp4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	0.145
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.143
Ngrn	neugrin, neurite outgrowth associated	0.135
Gins4	GINS complex subunit 4 (Sld5 homolog)	0.134
Mtx1	metaxin 1	0.127
Prdx3	peroxiredoxin 3	0.122
Exosc4	exosome component 4	0.119
Mrpl9	mitochondrial ribosomal protein L9	0.109
Coq9	coenzyme Q9 homolog (yeast)	0.107
Acyp1	acylphosphatase 1, erythrocyte (common) type	0.106
Ndufaf1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1	0.104
Mrpl49	mitochondrial ribosomal protein L49	0.101
Psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.096
Hagh	hydroxyacyl glutathione hydrolase	0.092
2310061C15Rik	RIKEN cDNA 2310061C15 gene	0.090
Jagn1	jagunal homolog 1 (Drosophila)	0.088
Gtf2h4	general transcription factor II H, polypeptide 4	0.086
Noc4l	nucleolar complex associated 4 homolog (S. cerevisiae)	0.085
Coq6	coenzyme Q6 homolog (yeast)	0.078
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.078
1700040I03Rik	RIKEN cDNA 1700040I03 gene	0.077
Eif2b1	eukaryotic translation initiation factor 2B, subunit 1 (alpha)	0.076
Ccdc142	coiled-coil domain containing 142	0.074
Foxred1	FAD-dependent oxidoreductase domain containing 1	0.073
Banf1	barrier to autointegration factor 1	0.072
Brp44	brain protein 44	0.069
2310011J03Rik	RIKEN cDNA 2310011J03 gene	0.068
Zswim7	zinc finger, SWIM-type containing 7	0.067
Thoc6	THO complex 6 homolog (Drosophila)	0.066
Ccdc56	coiled-coil domain containing 56	0.065
2410001C21Rik	RIKEN cDNA 2410001C21 gene	0.065
Nit2	nitrilase family, member 2	0.062
Triap1	TP53 regulated inhibitor of apoptosis 1	0.061
Dctpp1	dCTP pyrophosphatase 1	0.060
Sssca1	Sjogren's syndrome/scleroderma autoantigen 1 homolog (human)	0.059
Mrps28	mitochondrial ribosomal protein S28	0.059
Apip	APAF1 interacting protein	0.059
Wdr83	WD repeat domain containing 83	0.057
Ghitm	growth hormone inducible transmembrane protein	0.055
Rnaseh2a	ribonuclease H2, large subunit	0.055
Tmem208	transmembrane protein 208	0.054
Ssna1	Sjogren's syndrome nuclear autoantigen 1	0.054
Ccndbp1	cyclin D-type binding-protein 1	0.053
Ppp4c	protein phosphatase 4, catalytic subunit	0.053
Sirt3	sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)	0.052
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.052
Ubac1	ubiquitin associated domain containing 1	0.051
Aurkaip1	aurora kinase A interacting protein 1	0.050
Chmp6	chromatin modifying protein 6	0.049
2410091C18Rik	RIKEN cDNA 2410091C18 gene	0.049
Smn1	survival motor neuron 1	0.049
Slc30a6	solute carrier family 30 (zinc transporter), member 6	0.049
Eif6	eukaryotic translation initiation factor 6	0.045
Phb	prohibitin	0.044
AI462493	expressed sequence AI462493	0.044
Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit	0.044
Stk16	serine/threonine kinase 16	0.043
Etfdh	electron transferring flavoprotein, dehydrogenase	0.041
Sharpin	SHANK-associated RH domain interacting protein	0.040
5430437P03Rik	RIKEN cDNA 5430437P03 gene	0.040
Lrrc59	leucine rich repeat containing 59	0.039
1810009A15Rik	RIKEN cDNA 1810009A15 gene	0.038
Mlx	MAX-like protein X	0.038
Sec13	SEC13 homolog (S. cerevisiae)	0.037
Mrps27	mitochondrial ribosomal protein S27	0.037
Urod	uroporphyrinogen decarboxylase	0.036
Eefsec	eukaryotic elongation factor, selenocysteine-tRNA-specific	0.036
Scnm1	sodium channel modifier 1	0.036
Nme6	non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)	0.034
Ssr2	signal sequence receptor, beta	0.032
Nprl2	nitrogen permease regulator-like 2 (S. cerevisiae)	0.032
Eif2b2	eukaryotic translation initiation factor 2B, subunit 2 beta	0.031
Uxt	ubiquitously expressed transcript	0.031
Clpp	caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)	0.031
Mrpl55	mitochondrial ribosomal protein L55	0.031
Pnkp	polynucleotide kinase 3'- phosphatase	0.030
Lsg1	large subunit GTPase 1 homolog (S. cerevisiae)	0.030
Ifrd2	interferon-related developmental regulator 2	0.030
1810030N24Rik	RIKEN cDNA 1810030N24 gene	0.029
Pex7	peroxisomal biogenesis factor 7	0.029
Rab24	RAB24, member RAS oncogene family	0.029
Dap3	death associated protein 3	0.029
Pin1	protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1	0.028
Rbm19	RNA binding motif protein 19	0.028
Nsun4	NOL1/NOP2/Sun domain family, member 4	0.028
Tsta3	tissue specific transplantation antigen P35B	0.028
Bcs1l	BCS1-like (yeast)	0.028
Ak2	adenylate kinase 2	0.027
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.027
Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.027
Poldip2	polymerase (DNA-directed), delta interacting protein 2	0.026
Alg3	asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)	0.025
Ndufaf3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3	0.025
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.025
Mzt2	mitotic spindle organizing protein 2	0.024
Nudt16l1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	0.024
Mrpl10	mitochondrial ribosomal protein L10	0.024
Stoml2	stomatin (Epb7.2)-like 2	0.024
Isca2	iron-sulfur cluster assembly 2 homolog (S. cerevisiae)	0.024	Yeast
Cox4nb	COX4 neighbor	0.024
Ptpmt1	protein tyrosine phosphatase, mitochondrial 1	0.023
Drg2	developmentally regulated GTP binding protein 2	0.023
Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	0.023
0610009B22Rik	RIKEN cDNA 0610009B22 gene	0.022
Spryd4	SPRY domain containing 4	0.022
Elac2	elaC homolog 2 (E. coli)	0.022
Trap1	TNF receptor-associated protein 1	0.022
Grwd1	glutamate-rich WD repeat containing 1	0.022
Bpgm	2,3-bisphosphoglycerate mutase	0.022
Elof1	elongation factor 1 homolog (ELF1, S. cerevisiae)	0.021
Nkiras1	NFKB inhibitor interacting Ras-like protein 1	0.021
Mtg1	mitochondrial GTPase 1 homolog (S. cerevisiae)	0.021
Gfer	growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)	0.021
Rnf5	ring finger protein 5	0.021
Coq3	coenzyme Q3 homolog, methyltransferase (yeast)	0.020
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.020
Isyna1	myo-inositol 1-phosphate synthase A1	0.020
Mrpl46	mitochondrial ribosomal protein L46	0.020
Dhrs4	dehydrogenase/reductase (SDR family) member 4	0.020
Mecr	mitochondrial trans-2-enoyl-CoA reductase	0.019
Rrp36	ribosomal RNA processing 36 homolog (S. cerevisiae)	0.018
Cbr4	carbonyl reductase 4	0.018
U2af1l4	U2 small nuclear RNA auxiliary factor 1-like 4	0.018
Tmem179b	transmembrane protein 179B	0.018
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.018
Tarbp2	TAR (HIV) RNA binding protein 2	0.017
Exosc7	exosome component 7	0.017
Pus1	pseudouridine synthase 1	0.016
Mrpl44	mitochondrial ribosomal protein L44	0.016
Dctn3	dynactin 3	0.016
Pmm2	phosphomannomutase 2	0.016
Arfrp1	ADP-ribosylation factor related protein 1	0.016
Anapc16	anaphase promoting complex subunit 16	0.016
Tbrg4	transforming growth factor beta regulated gene 4	0.016
Mrpl36	mitochondrial ribosomal protein L36	0.016
Tmem97	transmembrane protein 97	0.016
Lace1	lactation elevated 1	0.015
Rangrf	RAN guanine nucleotide release factor	0.015
Ormdl2	ORM1-like 2 (S. cerevisiae)	0.015
Med27	mediator complex subunit 27	0.015
Ndufs4	NADH dehydrogenase (ubiquinone) Fe-S protein 4	0.015
Mxi1	Max interacting protein 1	0.015
Pdhx	pyruvate dehydrogenase complex, component X	0.015
BC031181	cDNA sequence BC031181	0.015
Sigmar1	sigma non-opioid intracellular receptor 1	0.015
Adsl	adenylosuccinate lyase	0.015
Nit1	nitrilase 1	0.015
Wdr55	WD repeat domain 55	0.015
Pdcd2l	programmed cell death 2-like	0.015
Nmnat1	nicotinamide nucleotide adenylyltransferase 1	0.015
Trappc5	trafficking protein particle complex 5	0.015
Tmem93	transmembrane protein 93	0.015
Mpdu1	mannose-P-dolichol utilization defect 1	0.015
Ftsj2	FtsJ homolog 2 (E. coli)	0.015
Galk2	galactokinase 2	0.014
3110001D03Rik	RIKEN cDNA 3110001D03 gene	0.014
Hsdl2	hydroxysteroid dehydrogenase like 2	0.014
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.014
Wdr74	WD repeat domain 74	0.014
3200002M19Rik	RIKEN cDNA 3200002M19 gene	0.014
Sirt7	sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae)	0.014
Rfc2	replication factor C (activator 1) 2	0.014
Pold2	polymerase (DNA directed), delta 2, regulatory subunit	0.013
Rnf167	ring finger protein 167	0.013
Mrpl39	mitochondrial ribosomal protein L39	0.013
Th1l	TH1-like homolog (Drosophila)	0.013
Tmem129	transmembrane protein 129	0.013
Isca1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)	0.013	Yeast
Psmb2	proteasome (prosome, macropain) subunit, beta type 2	0.013
Vars	valyl-tRNA synthetase	0.013
Ndufa8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8	0.013
D16H22S680E	DNA segment, Chr 16, human D22S680E, expressed	0.013
Ubxn8	UBX domain protein 8	0.013
Ppcs	phosphopantothenoylcysteine synthetase	0.013
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.013
Bysl	bystin-like	0.013
Ccdc86	coiled-coil domain containing 86	0.013
Asna1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	0.013
Rfk	riboflavin kinase	0.012
Clybl	citrate lyase beta like	0.012
Rpl7l1	ribosomal protein L7-like 1	0.012
Tmx2	thioredoxin-related transmembrane protein 2	0.012
Pde6d	phosphodiesterase 6D, cGMP-specific, rod, delta	0.012
Mad2l2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.012
Znhit2-ps	zinc finger, HIT domain containing 2, pseudogene	0.012
Lsm10	U7 snRNP-specific Sm-like protein LSM10	0.012
Ppil1	peptidylprolyl isomerase (cyclophilin)-like 1	0.011
Myg1	melanocyte proliferating gene 1	0.011
2510006D16Rik	RIKEN cDNA 2510006D16 gene	0.011
AU040320	expressed sequence AU040320	0.011
Wbscr22	Williams Beuren syndrome chromosome region 22	0.011
Mrps17	mitochondrial ribosomal protein S17	0.011
Hsbp1	heat shock factor binding protein 1	0.011
Sar1b	SAR1 gene homolog B (S. cerevisiae)	0.011
Tm2d2	TM2 domain containing 2	0.011
Bop1	block of proliferation 1	0.011
Nxt1	NTF2-related export protein 1	0.011
2010305A19Rik	RIKEN cDNA 2010305A19 gene	0.011
Bax	BCL2-associated X protein	0.011
Zc3hc1	zinc finger, C3HC type 1	0.011
Coq5	coenzyme Q5 homolog, methyltransferase (yeast)	0.011
Copz1	coatomer protein complex, subunit zeta 1	0.011
Mrrf	mitochondrial ribosome recycling factor	0.011
Cog4	component of oligomeric golgi complex 4	0.011
Nans	N-acetylneuraminic acid synthase (sialic acid synthase)	0.011
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.010
Pycrl	pyrroline-5-carboxylate reductase-like	0.010
Ddx49	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49	0.010
Tmem192	transmembrane protein 192	0.010
Eral1	Era (G-protein)-like 1 (E. coli)	0.010