IMP

Process View

Mus musculus

1 genes annotated in mouse

lateral line nerve development

The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lateral line nerve development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lateral line nerve development" (in gray)

Name	Description	Probability	Func Analog Organism
Phox2b	paired-like homeobox 2b	0.999
Msx1	homeobox, msh-like 1	0.998
Isl1	ISL1 transcription factor, LIM/homeodomain	0.998
Nrg1	neuregulin 1	0.997
Ret	ret proto-oncogene	0.996
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.992
Ntf3	neurotrophin 3	0.978
Chrd	chordin	0.958
Hoxa1	homeobox A1	0.895
Sox10	SRY-box containing gene 10	0.859
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.812
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.812	Zebrafish
Gdnf	glial cell line derived neurotrophic factor	0.692
Hand2	heart and neural crest derivatives expressed transcript 2	0.569
Tcfap2a	transcription factor AP-2, alpha	0.472
Ntf5	neurotrophin 5	0.376
Bdnf	brain derived neurotrophic factor	0.323
Gbx2	gastrulation brain homeobox 2	0.286
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.283	Zebrafish
Shh	sonic hedgehog	0.276
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.268
Eya1	eyes absent 1 homolog (Drosophila)	0.267
Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	0.267
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.244
Foxc1	forkhead box C1	0.237
Egr2	early growth response 2	0.221	Zebrafish
Phox2a	paired-like homeobox 2a	0.200	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.186
Pax3	paired box gene 3	0.175
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.158
Dlx5	distal-less homeobox 5	0.144
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.143
Ednra	endothelin receptor type A	0.142
Nrtn	neurturin	0.140
Fgf8	fibroblast growth factor 8	0.129
Sox9	SRY-box containing gene 9	0.128
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.124
Nab2	Ngfi-A binding protein 2	0.104
Tbx1	T-box 1	0.100
Hoxb1	homeobox B1	0.090
Hand1	heart and neural crest derivatives expressed transcript 1	0.085
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.082
Pitx1	paired-like homeodomain transcription factor 1	0.073
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.072
Tbx15	T-box 15	0.068
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.068
Bmp7	bone morphogenetic protein 7	0.067
Mecom	MDS1 and EVI1 complex locus	0.057
Prrx2	paired related homeobox 2	0.052	Mouse
Hoxa2	homeobox A2	0.050
Acvr1	activin A receptor, type 1	0.042
Gli3	GLI-Kruppel family member GLI3	0.042
Runx2	runt related transcription factor 2	0.040
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.040
Msx2	homeobox, msh-like 2	0.039
Bmp2	bone morphogenetic protein 2	0.038
Prrx1	paired related homeobox 1	0.036	Mouse
Nab1	Ngfi-A binding protein 1	0.034
Bmp4	bone morphogenetic protein 4	0.033
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.032
Dlx6	distal-less homeobox 6	0.032
Gsc	goosecoid homeobox	0.030
Hmx3	H6 homeobox 3	0.023
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.022
Pax9	paired box gene 9	0.022
Fgfr1	fibroblast growth factor receptor 1	0.022
Neurod1	neurogenic differentiation 1	0.021
Nf1	neurofibromatosis 1	0.020
Foxc2	forkhead box C2	0.020
Prph	peripherin	0.020
Zic2	zinc finger protein of the cerebellum 2	0.020
En1	engrailed 1	0.019
Nkx3-2	NK3 homeobox 2	0.019
Twist2	twist homolog 2 (Drosophila)	0.019
Otx2	orthodenticle homolog 2 (Drosophila)	0.018
Fgf15	fibroblast growth factor 15	0.018
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.017
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.017
Egr1	early growth response 1	0.017
Pmp22	peripheral myelin protein 22	0.016
Pax6	paired box gene 6	0.016
Lama4	laminin, alpha 4	0.016
Krt17	keratin 17	0.016
Pbx1	pre B-cell leukemia transcription factor 1	0.015
Twist1	twist homolog 1 (Drosophila)	0.015
Alx1	ALX homeobox 1	0.015
Tcf15	transcription factor 15	0.015
Egr3	early growth response 3	0.014
Sall4	sal-like 4 (Drosophila)	0.014
Robo3	roundabout homolog 3 (Drosophila)	0.013
Hoxd11	homeobox D11	0.013
Fgfr2	fibroblast growth factor receptor 2	0.012
Smo	smoothened homolog (Drosophila)	0.012
Fgf17	fibroblast growth factor 17	0.012
Dmrt3	doublesex and mab-3 related transcription factor 3	0.012
Dlx2	distal-less homeobox 2	0.012
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Cdx2	caudal type homeobox 2	0.011
Ednrb	endothelin receptor type B	0.011
Hoxb9	homeobox B9	0.011
Ngf	nerve growth factor	0.011
Foxd2	forkhead box D2	0.011
Wnt6	wingless-related MMTV integration site 6	0.011
Myog	myogenin	0.011
Hoxb13	homeobox B13	0.011
Chst14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14	0.011
Hmx2	H6 homeobox 2	0.011
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.010
Gsx2	GS homeobox 2	0.010
Chd7	chromodomain helicase DNA binding protein 7	0.010
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.010
Tal2	T-cell acute lymphocytic leukemia 2	0.010
Gli2	GLI-Kruppel family member GLI2	0.010