IMP

Process View

Mus musculus

2 genes annotated in mouse

renal tubular secretion

Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal tubular secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal tubular secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.921	Mouse
G6pc	glucose-6-phosphatase, catalytic	0.906
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.892
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.862	Mouse
Keg1	kidney expressed gene 1	0.840
Alb	albumin	0.839
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.837
Akr1c6	aldo-keto reductase family 1, member C6	0.777
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.760	Mouse
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.755
Cps1	carbamoyl-phosphate synthetase 1	0.741
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.674	Mouse
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.674
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.654	Mouse
Pigr	polymeric immunoglobulin receptor	0.649
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.623	Mouse
Crp	C-reactive protein, pentraxin-related	0.579
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.538	Mouse
Azgp1	alpha-2-glycoprotein 1, zinc	0.500
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.482	Mouse
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.479	Mouse
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.417
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.401
Cml2	camello-like 2	0.398
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.397	Mouse
Mup5	major urinary protein 5	0.339
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.326
Krtap6-1	keratin associated protein 6-1	0.321
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.300	Mouse
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.286
Hgd	homogentisate 1, 2-dioxygenase	0.278
Inmt	indolethylamine N-methyltransferase	0.274
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.271
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.266
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.250
Upp2	uridine phosphorylase 2	0.249
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.249
Apoh	apolipoprotein H	0.248
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.238
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.236
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.197	Mouse
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.191
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.182
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.172
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.172
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.159
F9	coagulation factor IX	0.157
Otc	ornithine transcarbamylase	0.145
Fmo3	flavin containing monooxygenase 3	0.142
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.140
Hamp	hepcidin antimicrobial peptide	0.131
Ppl	periplakin	0.126
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.124
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.124
Aadac	arylacetamide deacetylase (esterase)	0.118
F13b	coagulation factor XIII, beta subunit	0.110
C9	complement component 9	0.109
Dmgdh	dimethylglycine dehydrogenase precursor	0.101
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.101
Akr1d1	aldo-keto reductase family 1, member D1	0.100
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.099
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.098
Pon1	paraoxonase 1	0.092
Tat	tyrosine aminotransferase	0.091
Sult1d1	sulfotransferase family 1D, member 1	0.091
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.088
Inhbc	inhibin beta-C	0.086
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.084
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.084
Slc17a3	solute carrier family 17 (sodium phosphate), member 3	0.081
Ces1d	carboxylesterase 1D	0.080
Fmo1	flavin containing monooxygenase 1	0.075
Apoc4	apolipoprotein C-IV	0.075
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.073	Mouse
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.071
Vnn3	vanin 3	0.070
Bche	butyrylcholinesterase	0.064
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.063
Krt6b	keratin 6B	0.063
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.063
Tdo2	tryptophan 2,3-dioxygenase	0.062
Cfhr1	complement factor H-related 1	0.062
Afm	afamin	0.061
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.059
Dct	dopachrome tautomerase	0.059
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.056
Hc	hemolytic complement	0.056
Krtap4-16	keratin associated protein 4-16	0.054
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.053
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.052
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.051
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.050
Hrg	histidine-rich glycoprotein	0.049
Krtap5-1	keratin associated protein 5-1	0.048
Ces1g	carboxylesterase 1G	0.048
BC089597	cDNA sequence BC089597	0.046
Lce1i	late cornified envelope 1I	0.046
Olfr67	olfactory receptor 67	0.045
Hoga1	4-hydroxy-2-oxoglutarate aldolase 1	0.044
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.043
Iyd	iodotyrosine deiodinase	0.043
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.042
Ttc36	tetratricopeptide repeat domain 36	0.042
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.040
Btc	betacellulin, epidermal growth factor family member	0.038
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.038
C8a	complement component 8, alpha polypeptide	0.038
Vsig4	V-set and immunoglobulin domain containing 4	0.037
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.036
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.036
Pah	phenylalanine hydroxylase	0.036
Rptn	repetin	0.036
Kap	kidney androgen regulated protein	0.035
Tas2r105	taste receptor, type 2, member 105	0.034
Gc	group specific component	0.034
Mbl1	mannose-binding lectin (protein A) 1	0.034
Lce1b	late cornified envelope 1B	0.033
Cyp2c44	cytochrome P450, family 2, subfamily c, polypeptide 44	0.032
Olfr49	olfactory receptor 49	0.032
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.031
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.030
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.030
Il1f5	interleukin 1 family, member 5 (delta)	0.030
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.030
Hsd3b4	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4	0.030
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.029
Cox8c	cytochrome c oxidase, subunit VIIIc	0.029
Sult1b1	sulfotransferase family 1B, member 1	0.028
Lect2	leukocyte cell-derived chemotaxin 2	0.028
Dio1	deiodinase, iodothyronine, type I	0.027
Apob	apolipoprotein B	0.027
Oprk1	opioid receptor, kappa 1	0.027
Cdh9	cadherin 9	0.026
Prodh2	proline dehydrogenase (oxidase) 2	0.026
Sardh	sarcosine dehydrogenase	0.026
Fmo2	flavin containing monooxygenase 2	0.026
Olfr74	olfactory receptor 74	0.026
Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a	0.026
Ppara	peroxisome proliferator activated receptor alpha	0.026
Krt86	keratin 86	0.025
Nat8	N-acetyltransferase 8 (GCN5-related, putative)	0.025
Agmat	agmatine ureohydrolase (agmatinase)	0.024
Prlr	prolactin receptor	0.024
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.024
Slc12a1	solute carrier family 12, member 1	0.024
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.024
Bhmt2	betaine-homocysteine methyltransferase 2	0.024
Slco1a6	solute carrier organic anion transporter family, member 1a6	0.023
Krtap13	keratin associated protein 13	0.023
Fgf1	fibroblast growth factor 1	0.023
Mbl2	mannose-binding lectin (protein C) 2	0.023
Gpr182	G protein-coupled receptor 182	0.022
Acot3	acyl-CoA thioesterase 3	0.022
Gm14743	predicted gene 14743	0.021
Krt32	keratin 32	0.021
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.021
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.021
Olfr1508	olfactory receptor 1508	0.021
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.021
Glyat	glycine-N-acyltransferase	0.021
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.020
Rdh16	retinol dehydrogenase 16	0.020
Apoc3	apolipoprotein C-III	0.020
Gpx6	glutathione peroxidase 6	0.020
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.020	Mouse
Aldob	aldolase B, fructose-bisphosphate	0.019
Yipf7	Yip1 domain family, member 7	0.019
Fbp1	fructose bisphosphatase 1	0.019
Mettl7b	methyltransferase like 7B	0.019
Lce1a1	late cornified envelope 1A1	0.019
Akr1c21	aldo-keto reductase family 1, member C21	0.018
Mup19	major urinary protein 19	0.018
Fmo5	flavin containing monooxygenase 5	0.018
Defb1	defensin beta 1	0.018
Ces1f	carboxylesterase 1F	0.018
Umod	uromodulin	0.018
Creb3l3	cAMP responsive element binding protein 3-like 3	0.018
Cldn2	claudin 2	0.018
D730048I06Rik	RIKEN cDNA D730048I06 gene	0.017
Psapl1	prosaposin-like 1	0.017
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.017	Mouse
Csn2	casein beta	0.017
Pipox	pipecolic acid oxidase	0.017
Cyp4f15	cytochrome P450, family 4, subfamily f, polypeptide 15	0.017
Cfhr2	complement factor H-related 2	0.016
Rdh7	retinol dehydrogenase 7	0.016
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.016	Mouse
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.016
Neu2	neuraminidase 2	0.016
Npy6r	neuropeptide Y receptor Y6	0.016
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.015
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.015
Slc18a1	solute carrier family 18 (vesicular monoamine), member 1	0.015
Mat1a	methionine adenosyltransferase I, alpha	0.015
Krtap5-2	keratin associated protein 5-2	0.015
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.015
Olfr480	olfactory receptor 480	0.015
Avpr1a	arginine vasopressin receptor 1A	0.014
Omd	osteomodulin	0.014
C80012	expressed sequence C80012	0.014
Dpys	dihydropyrimidinase	0.014
Csn1s1	casein alpha s1	0.014
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.014
Ephx2	epoxide hydrolase 2, cytoplasmic	0.014
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.013
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.013
2810459M11Rik	RIKEN cDNA 2810459M11 gene	0.013
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.013
Adh1	alcohol dehydrogenase 1 (class I)	0.013
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.013
Orm3	orosomucoid 3	0.013
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.013
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.012
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.012
Bhmt	betaine-homocysteine methyltransferase	0.012
Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.012
Ces1e	carboxylesterase 1E	0.012
Acnat2	acyl-coenzyme A amino acid N-acyltransferase 2	0.012
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.012
Acsm1	acyl-CoA synthetase medium-chain family member 1	0.012
Kprp	keratinocyte expressed, proline-rich	0.012
Klkb1	kallikrein B, plasma 1	0.012
Acot12	acyl-CoA thioesterase 12	0.012
Col4a3	collagen, type IV, alpha 3	0.012
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.012
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.012
Aym1	activator of yeast meiotic promoters 1	0.011
Mep1a	meprin 1 alpha	0.011
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.011
Cyp2b19	cytochrome P450, family 2, subfamily b, polypeptide 19	0.011	Mouse
Tff1	trefoil factor 1	0.011
Defb11	defensin beta 11	0.011
Mc2r	melanocortin 2 receptor	0.011
Mup3	major urinary protein 3	0.011
Cyp4a32	cytochrome P450, family 4, subfamily a, polypeptide 32	0.011
H2-Q10	histocompatibility 2, Q region locus 10	0.011
Krt4	keratin 4	0.011
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.011
Lao1	L-amino acid oxidase 1	0.011
Mrap	melanocortin 2 receptor accessory protein	0.011
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.011
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.011
Nrg4	neuregulin 4	0.010
Mrgpra3	MAS-related GPR, member A3	0.010
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.010
Gsta3	glutathione S-transferase, alpha 3	0.010
Serpinb11	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11	0.010
Sprr2d	small proline-rich protein 2D	0.010
Cyp2c69	cytochrome P450, family 2, subfamily c, polypeptide 69	0.010
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.010