IMP

Process View

Mus musculus

11 genes annotated in mouse

Multi-species View

negative regulation of coagulation

GO:0050819

Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of coagulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of coagulation" (in gray)

Name	Description	Probability	Func Analog Organism
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.900
Plg	plasminogen	0.820	Human Mouse
Apoa1	apolipoprotein A-I	0.630
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.521
Fgg	fibrinogen gamma chain	0.427
F2	coagulation factor II	0.423	Human Mouse
Dysf	dysferlin	0.350
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.336
Cfi	complement component factor i	0.298
F7	coagulation factor VII	0.291	Mouse
Itgb3	integrin beta 3	0.287
Asgr2	asialoglycoprotein receptor 2	0.256
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.238
Saa4	serum amyloid A 4	0.215
ND6	NADH dehydrogenase subunit 6	0.184
Pzp	pregnancy zone protein	0.176
Proc	protein C	0.169
Plau	plasminogen activator, urokinase	0.165
Ambp	alpha 1 microglobulin/bikunin	0.162
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.161
Kng1	kininogen 1	0.160	Human
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.156
C9	complement component 9	0.144
Fgb	fibrinogen beta chain	0.143
Gc	group specific component	0.142
Lgals3	lectin, galactose binding, soluble 3	0.141
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.138
F9	coagulation factor IX	0.136	Mouse
Gcgr	glucagon receptor	0.129
Igfbp1	insulin-like growth factor binding protein 1	0.121
Apoa5	apolipoprotein A-V	0.116
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.106
Fga	fibrinogen alpha chain	0.105
Ptgs2	prostaglandin-endoperoxide synthase 2	0.102
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.095
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.093
F10	coagulation factor X	0.092	Mouse
F12	coagulation factor XII (Hageman factor)	0.090	Human Mouse
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.086
Hgd	homogentisate 1, 2-dioxygenase	0.080
Nos1	nitric oxide synthase 1, neuronal	0.077
Trfr2	transferrin receptor 2	0.076
S100a10	S100 calcium binding protein A10 (calpactin)	0.075
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.073
Plat	plasminogen activator, tissue	0.066	Mouse
F11	coagulation factor XI	0.064	Human
Hnf4a	hepatic nuclear factor 4, alpha	0.060
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.059
Apom	apolipoprotein M	0.058
Spna1	spectrin alpha 1	0.058
Prodh2	proline dehydrogenase (oxidase) 2	0.057
Hc	hemolytic complement	0.056
Hbb-b1	hemoglobin, beta adult major chain	0.055
Apoa4	apolipoprotein A-IV	0.055
Hpx	hemopexin	0.054
Lipc	lipase, hepatic	0.053
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.052
Foxa3	forkhead box A3	0.049
Hgfac	hepatocyte growth factor activator	0.046	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.044
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.043
Mmp9	matrix metallopeptidase 9	0.041
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.038
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.037
Hamp	hepcidin antimicrobial peptide	0.037
Agxt	alanine-glyoxylate aminotransferase	0.036
Psg21	pregnancy-specific glycoprotein 21	0.035	Mouse
Ahsg	alpha-2-HS-glycoprotein	0.034	Mouse
Apob	apolipoprotein B	0.034
Hal	histidine ammonia lyase	0.033
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.033	Human Rat
Tnc	tenascin C	0.032
Mat1a	methionine adenosyltransferase I, alpha	0.031
Cpn1	carboxypeptidase N, polypeptide 1	0.031
Ldb3	LIM domain binding 3	0.030
Amdhd1	amidohydrolase domain containing 1	0.030
Lox	lysyl oxidase	0.029
Apoc4	apolipoprotein C-IV	0.029
Afm	afamin	0.029
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.029
Mpl	myeloproliferative leukemia virus oncogene	0.028
Egfr	epidermal growth factor receptor	0.027
Ces1c	carboxylesterase 1C	0.026
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.026
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.025
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.025
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.025
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.024	Mouse
Pea15a	phosphoprotein enriched in astrocytes 15A	0.022
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.022
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.022
Apof	apolipoprotein F	0.022
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.022
Mup3	major urinary protein 3	0.021
Cd9	CD9 antigen	0.021
Mmp2	matrix metallopeptidase 2	0.020
Cyr61	cysteine rich protein 61	0.020
Gp9	glycoprotein 9 (platelet)	0.020
Aadat	aminoadipate aminotransferase	0.020
Prkce	protein kinase C, epsilon	0.020
Mbl2	mannose-binding lectin (protein C) 2	0.019
Sri	sorcin	0.019
Anxa3	annexin A3	0.019
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.019
Alb	albumin	0.018
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.018
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.018
Osmr	oncostatin M receptor	0.018
Ptges	prostaglandin E synthase	0.018
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.017
Klf1	Kruppel-like factor 1 (erythroid)	0.017
Crb2	crumbs homolog 2 (Drosophila)	0.017
Msln	mesothelin	0.017
Pah	phenylalanine hydroxylase	0.017
Slc3a1	solute carrier family 3, member 1	0.016
Anxa5	annexin A5	0.016	Mouse
S100a6	S100 calcium binding protein A6 (calcyclin)	0.016
Apcs	serum amyloid P-component	0.016
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.016
C5ar1	complement component 5a receptor 1	0.016
Wdr1	WD repeat domain 1	0.016
Ilk	integrin linked kinase	0.015
Gulo	gulonolactone (L-) oxidase	0.015
Lmna	lamin A	0.015
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.015
Rp1	retinitis pigmentosa 1 (human)	0.015
Crp	C-reactive protein, pentraxin-related	0.015
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.015
Dmgdh	dimethylglycine dehydrogenase precursor	0.014
Trim10	tripartite motif-containing 10	0.014
Masp2	mannan-binding lectin serine peptidase 2	0.014
Ank1	ankyrin 1, erythroid	0.014
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.013
Orai1	ORAI calcium release-activated calcium modulator 1	0.013
Masp1	mannan-binding lectin serine peptidase 1	0.013
Aqp9	aquaporin 9	0.013
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.013
Cfh	complement component factor h	0.013
Pparg	peroxisome proliferator activated receptor gamma	0.013
Thbs2	thrombospondin 2	0.013
Apoa2	apolipoprotein A-II	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.012	Mouse
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.012
Tdo2	tryptophan 2,3-dioxygenase	0.012
Klk1b1	kallikrein 1-related peptidase b1	0.012
Prnp	prion protein	0.012
Msn	moesin	0.012
Mug2	murinoglobulin 2	0.012
F13b	coagulation factor XIII, beta subunit	0.012
Vnn3	vanin 3	0.012
Psg17	pregnancy specific glycoprotein 17	0.012
Pklr	pyruvate kinase liver and red blood cell	0.012
Selp	selectin, platelet	0.012
Mbl1	mannose-binding lectin (protein A) 1	0.012
Orm2	orosomucoid 2	0.012
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.011
Emp1	epithelial membrane protein 1	0.011
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.011
C8b	complement component 8, beta polypeptide	0.011
Tat	tyrosine aminotransferase	0.011
Mug1	murinoglobulin 1	0.011
Prl3b1	prolactin family 3, subfamily b, member 1	0.011
Lect2	leukocyte cell-derived chemotaxin 2	0.011
Gpr97	G protein-coupled receptor 97	0.010
Hbegf	heparin-binding EGF-like growth factor	0.010
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.010
Pcdh12	protocadherin 12	0.010
Nupr1	nuclear protein 1	0.010
Inhbe	inhibin beta E	0.010
Ier3	immediate early response 3	0.010