IMP

Process View

Mus musculus

9 genes annotated in mouse

dopamine secretion

The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dopamine secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dopamine secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	1.000
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.998
Chrnb4	cholinergic receptor, nicotinic, beta polypeptide 4	0.994	Mouse
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.962	Mouse
Drd2	dopamine receptor D2	0.853
Nos1	nitric oxide synthase 1, neuronal	0.530
Ache	acetylcholinesterase	0.384
Pitx3	paired-like homeodomain transcription factor 3	0.338
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.276
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.241
Lhx3	LIM homeobox protein 3	0.231
Oprm1	opioid receptor, mu 1	0.213
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.212
Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	0.193
Cplx1	complexin 1	0.137
Chrna10	cholinergic receptor, nicotinic, alpha polypeptide 10	0.126	Mouse
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.125
Grm2	glutamate receptor, metabotropic 2	0.113
Pomc	pro-opiomelanocortin-alpha	0.111
Lpar5	lysophosphatidic acid receptor 5	0.097
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.093
Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3	0.081
Emx1	empty spiracles homolog 1 (Drosophila)	0.074
Stk32b	serine/threonine kinase 32B	0.073
Thrb	thyroid hormone receptor beta	0.068
Oprl1	opioid receptor-like 1	0.068
Rit2	Ras-like without CAAX 2	0.066
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.066
Drd1a	dopamine receptor D1A	0.063
Sult4a1	sulfotransferase family 4A, member 1	0.063
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.060	Mouse
C1ql1	complement component 1, q subcomponent-like 1	0.058
Gjd2	gap junction protein, delta 2	0.056
Fshr	follicle stimulating hormone receptor	0.056
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.053
Mab21l2	mab-21-like 2 (C. elegans)	0.053
Neurod2	neurogenic differentiation 2	0.052
Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	0.052
Cnr1	cannabinoid receptor 1 (brain)	0.051	Rat
Alk	anaplastic lymphoma kinase	0.050
Rgs8	regulator of G-protein signaling 8	0.048
Syt1	synaptotagmin I	0.048
Gal	galanin	0.047
Syt13	synaptotagmin XIII	0.046
Esrrb	estrogen related receptor, beta	0.045
Nell2	NEL-like 2 (chicken)	0.043
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.043
Ebf3	early B-cell factor 3	0.041
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.040
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.040
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.040
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.040
Ank1	ankyrin 1, erythroid	0.038
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.037
Myog	myogenin	0.037
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.037
Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.036
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.034
Pspn	persephin	0.033
Rapsn	receptor-associated protein of the synapse	0.031
Olfr140	olfactory receptor 140	0.029
Cga	glycoprotein hormones, alpha subunit	0.028
Adora2a	adenosine A2a receptor	0.027
Lcn8	lipocalin 8	0.027
Scgn	secretagogin, EF-hand calcium binding protein	0.026
Mybph	myosin binding protein H	0.026
Cox8c	cytochrome c oxidase, subunit VIIIc	0.026
Slc30a3	solute carrier family 30 (zinc transporter), member 3	0.026
Cntn2	contactin 2	0.025
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.025
Krt12	keratin 12	0.024
Apc2	adenomatosis polyposis coli 2	0.023
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.023
Tff1	trefoil factor 1	0.023
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.023
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.023
Dcx	doublecortin	0.023
Fgf3	fibroblast growth factor 3	0.023
Myod1	myogenic differentiation 1	0.022
Vsx2	visual system homeobox 2	0.022
Snca	synuclein, alpha	0.022
Chrna9	cholinergic receptor, nicotinic, alpha polypeptide 9	0.022	Mouse
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.022
Calb2	calbindin 2	0.022
Sstr1	somatostatin receptor 1	0.020
Gnrh1	gonadotropin releasing hormone 1	0.020
Th	tyrosine hydroxylase	0.020
Glra1	glycine receptor, alpha 1 subunit	0.020
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.019
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.018
Nhlh1	nescient helix loop helix 1	0.018
Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	0.018
Ptprn	protein tyrosine phosphatase, receptor type, N	0.018
Psapl1	prosaposin-like 1	0.018
Gnao1	guanine nucleotide binding protein, alpha O	0.018
Smyd1	SET and MYND domain containing 1	0.017
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.017
Musk	muscle, skeletal, receptor tyrosine kinase	0.017
Znrf4	zinc and ring finger 4	0.017
Accn4	amiloride-sensitive cation channel 4, pituitary	0.017
Aanat	arylalkylamine N-acetyltransferase	0.016
Krtap5-1	keratin associated protein 5-1	0.016
Apln	apelin	0.016
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.016
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.016
Sox10	SRY-box containing gene 10	0.016
Crhr1	corticotropin releasing hormone receptor 1	0.015
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.015
Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.015
Rgs4	regulator of G-protein signaling 4	0.015
Nxnl2	nucleoredoxin-like 2	0.015
Sstr4	somatostatin receptor 4	0.015
Has1	hyaluronan synthase1	0.015
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.014	Mouse
Gpr33	G protein-coupled receptor 33	0.014
Rho	rhodopsin	0.014
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.014
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.014
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.014	Rat
Cryaa	crystallin, alpha A	0.014
Dtna	dystrobrevin alpha	0.014
Syn2	synapsin II	0.014
Nxph1	neurexophilin 1	0.014
Fgf14	fibroblast growth factor 14	0.014
Plp1	proteolipid protein (myelin) 1	0.014
Gzmm	granzyme M (lymphocyte met-ase 1)	0.014
Myo15	myosin XV	0.014
Hap1	huntingtin-associated protein 1	0.014
Wwox	WW domain-containing oxidoreductase	0.013
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.013
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.013
Cplx2	complexin 2	0.013
Olfr16	olfactory receptor 16	0.013
Mc3r	melanocortin 3 receptor	0.013
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.013
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.013
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.013
Spp2	secreted phosphoprotein 2	0.012
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.012
Trpm5	transient receptor potential cation channel, subfamily M, member 5	0.012
Ptpru	protein tyrosine phosphatase, receptor type, U	0.012
Gad2	glutamic acid decarboxylase 2	0.012
Onecut1	one cut domain, family member 1	0.012
Drd4	dopamine receptor D4	0.012	Mouse
Isl2	insulin related protein 2 (islet 2)	0.012
Abcg4	ATP-binding cassette, sub-family G (WHITE), member 4	0.012
Tcta	T-cell leukemia translocation altered gene	0.012
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.012	Mouse
Stx1b	syntaxin 1B	0.012
Dtnb	dystrobrevin, beta	0.012
Ghrl	ghrelin	0.012
Cno	cappuccino	0.011
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.011
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.011
Nrsn1	neurensin 1	0.011
Dpf3	D4, zinc and double PHD fingers, family 3	0.011
Cldn26	claudin 26	0.011
Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5	0.011	Mouse
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.011
Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	0.011
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.011
Tssk1	testis-specific serine kinase 1	0.010
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.010
Pde6c	phosphodiesterase 6C, cGMP specific, cone, alpha prime	0.010
Gcgr	glucagon receptor	0.010
Prph	peripherin	0.010