Process View
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dna duplex unwinding"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.930 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.860 | Yeast Fly | |
| Cdt1 | chromatin licensing and DNA replication factor 1 | 0.705 | ||
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.611 | ||
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.507 | Yeast Fly | |
| Brca2 | breast cancer 2 | 0.303 | ||
| Timeless | timeless homolog (Drosophila) | 0.276 | ||
| Brca1 | breast cancer 1 | 0.260 | ||
| Rrm1 | ribonucleotide reductase M1 | 0.215 | ||
| Rfc2 | replication factor C (activator 1) 2 | 0.108 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.096 | ||
| Pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.083 | ||
| Nup93 | nucleoporin 93 | 0.067 | ||
| Mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.060 | Human | |
| Atm | ataxia telangiectasia mutated homolog (human) | 0.056 | ||
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.045 | ||
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.042 | ||
| Ruvbl1 | RuvB-like protein 1 | 0.040 | ||
| Pold2 | polymerase (DNA directed), delta 2, regulatory subunit | 0.037 | ||
| Nup85 | nucleoporin 85 | 0.036 | ||
| Rfc1 | replication factor C (activator 1) 1 | 0.034 | ||
| Hells | helicase, lymphoid specific | 0.032 | ||
| Lig1 | ligase I, DNA, ATP-dependent | 0.023 | ||
| Cdca7l | cell division cycle associated 7 like | 0.021 | ||
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.021 | ||
| Rfc3 | replication factor C (activator 1) 3 | 0.020 | ||
| Fen1 | flap structure specific endonuclease 1 | 0.020 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.020 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.020 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.019 | ||
| Pole | polymerase (DNA directed), epsilon | 0.018 | ||
| Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.017 | ||
| Nup107 | nucleoporin 107 | 0.017 | ||
| Cdca7 | cell division cycle associated 7 | 0.017 | ||
| Rfc5 | replication factor C (activator 1) 5 | 0.016 | ||
| Pola1 | polymerase (DNA directed), alpha 1 | 0.016 | ||
| Dnajc9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.015 | ||
| Prim1 | DNA primase, p49 subunit | 0.015 | ||
| Eftud2 | elongation factor Tu GTP binding domain containing 2 | 0.014 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.014 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.013 | ||
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.012 | ||
| Ung | uracil DNA glycosylase | 0.012 | ||
| Aaas | achalasia, adrenocortical insufficiency, alacrimia | 0.011 | ||
| Nbn | nibrin | 0.010 | Human | |
| Lrwd1 | leucine-rich repeats and WD repeat domain containing 1 | 0.010 |