Process View
The process in which a lung bud bifurcates parallel to the plane of the previous bud.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "planar dichotomous subdivision of terminal units involved in lung branching morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Dvl2 | dishevelled 2, dsh homolog (Drosophila) | 1.000 | ||
| Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.957 | ||
| Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.931 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.896 | ||
| Jag1 | jagged 1 | 0.794 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.758 | ||
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.726 | ||
| Mks1 | Meckel syndrome, type 1 | 0.682 | ||
| Foxc1 | forkhead box C1 | 0.674 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.660 | ||
| Foxg1 | forkhead box G1 | 0.626 | ||
| Shh | sonic hedgehog | 0.616 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.570 | ||
| Efnb2 | ephrin B2 | 0.548 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.539 | ||
| Pax2 | paired box gene 2 | 0.524 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.454 | ||
| Foxc2 | forkhead box C2 | 0.429 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.368 | ||
| Dnahc11 | dynein, axonemal, heavy chain 11 | 0.323 | ||
| Sox11 | SRY-box containing gene 11 | 0.314 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.313 | ||
| Sox2 | SRY-box containing gene 2 | 0.257 | ||
| Meox2 | mesenchyme homeobox 2 | 0.241 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.235 | ||
| Smo | smoothened homolog (Drosophila) | 0.217 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.203 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.172 | ||
| Psen1 | presenilin 1 | 0.164 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.148 | ||
| Gata3 | GATA binding protein 3 | 0.133 | ||
| Celsr1 | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 0.126 | ||
| Chrd | chordin | 0.102 | ||
| Hoxa1 | homeobox A1 | 0.099 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.094 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.091 | ||
| Rb1 | retinoblastoma 1 | 0.085 | ||
| Myo6 | myosin VI | 0.083 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.075 | ||
| Kif3a | kinesin family member 3A | 0.074 | ||
| Rarb | retinoic acid receptor, beta | 0.072 | ||
| Foxj1 | forkhead box J1 | 0.071 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.067 | ||
| Tbx1 | T-box 1 | 0.064 | ||
| Noto | notochord homolog (Xenopus laevis) | 0.062 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.061 | ||
| Ptch1 | patched homolog 1 | 0.058 | ||
| Sox9 | SRY-box containing gene 9 | 0.055 | ||
| Itga3 | integrin alpha 3 | 0.053 | ||
| Invs | inversin | 0.050 | ||
| Rarg | retinoic acid receptor, gamma | 0.046 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.044 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.042 | ||
| Vegfa | vascular endothelial growth factor A | 0.037 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.031 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.031 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.029 | ||
| Cacng4 | calcium channel, voltage-dependent, gamma subunit 4 | 0.028 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.027 | ||
| Sfrp2 | secreted frizzled-related protein 2 | 0.025 | ||
| Sox4 | SRY-box containing gene 4 | 0.024 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.022 | ||
| Arhgap33 | Rho GTPase activating protein 33 | 0.021 | ||
| Egfr | epidermal growth factor receptor | 0.019 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.017 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.017 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.017 | ||
| H1fx | H1 histone family, member X | 0.016 | ||
| Ankrd6 | ankyrin repeat domain 6 | 0.016 | ||
| Spry2 | sprouty homolog 2 (Drosophila) | 0.016 | ||
| Rara | retinoic acid receptor, alpha | 0.015 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.015 | ||
| Slc26a4 | solute carrier family 26, member 4 | 0.015 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.014 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.014 | ||
| Gja1 | gap junction protein, alpha 1 | 0.014 | ||
| Rxra | retinoid X receptor alpha | 0.014 | ||
| Tmem67 | transmembrane protein 67 | 0.014 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.013 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.013 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.013 | ||
| Plxna3 | plexin A3 | 0.013 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.012 | ||
| Grik5 | glutamate receptor, ionotropic, kainate 5 (gamma 2) | 0.012 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.012 | ||
| Msx1 | homeobox, msh-like 1 | 0.012 | ||
| Ldoc1l | leucine zipper, down-regulated in cancer 1-like | 0.011 | ||
| Nog | noggin | 0.011 | ||
| Pax3 | paired box gene 3 | 0.010 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.010 |