IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

positive regulation of interleukin 10 secretion

GO:2001181

Any process that activates or increases the frequency, rate or extent of interleukin-10 secretion.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of interleukin 10 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of interleukin 10 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Casp1	caspase 1	0.598
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.530
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.377
Aim2	absent in melanoma 2	0.367
Vhl	von Hippel-Lindau tumor suppressor	0.360
Ldb3	LIM domain binding 3	0.357
Gbp5	guanylate binding protein 5	0.352
Prkce	protein kinase C, epsilon	0.350
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.235
Akt1	thymoma viral proto-oncogene 1	0.207	Mouse
Ilk	integrin linked kinase	0.194
Arpc4	actin related protein 2/3 complex, subunit 4	0.187
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.176
Bcl2	B-cell leukemia/lymphoma 2	0.151
Akt2	thymoma viral proto-oncogene 2	0.120	Mouse
Pparg	peroxisome proliferator activated receptor gamma	0.117
Csnk1g2	casein kinase 1, gamma 2	0.108
Actn2	actinin alpha 2	0.089
Cd28	CD28 antigen	0.087
Cd19	CD19 antigen	0.084
Wdr1	WD repeat domain 1	0.073
Mapkap1	mitogen-activated protein kinase associated protein 1	0.069
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.068
Blnk	B-cell linker	0.066
Mapkapk2	MAP kinase-activated protein kinase 2	0.061
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.057
Prkcb	protein kinase C, beta	0.053
Mlf2	myeloid leukemia factor 2	0.052
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.050
Lepr	leptin receptor	0.048
Vegfa	vascular endothelial growth factor A	0.047
Plcb1	phospholipase C, beta 1	0.047
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.045
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.044
Capn1	calpain 1	0.042
Vasp	vasodilator-stimulated phosphoprotein	0.041
Kctd20	potassium channel tetramerisation domain containing 20	0.039
Nlrp3	NLR family, pyrin domain containing 3	0.038
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.038
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.036
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.033
Igf1r	insulin-like growth factor I receptor	0.030
Cdk14	cyclin-dependent kinase 14	0.030
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.030
Fas	Fas (TNF receptor superfamily member 6)	0.029
Homer1	homer homolog 1 (Drosophila)	0.029
Igh	immunoglobulin heavy chain complex	0.026
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.026
Rasgrp1	RAS guanyl releasing protein 1	0.025
Cd40	CD40 antigen	0.025
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.025
Coro1c	coronin, actin binding protein 1C	0.024
Tgfbr1	transforming growth factor, beta receptor I	0.023
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.023
Gipc1	GIPC PDZ domain containing family, member 1	0.023
Cd151	CD151 antigen	0.023
Actn4	actinin alpha 4	0.023
Nos1	nitric oxide synthase 1, neuronal	0.021
Ctdnep1	CTD nuclear envelope phosphatase 1	0.020
Arhgap1	Rho GTPase activating protein 1	0.020
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.020
Dlg4	discs, large homolog 4 (Drosophila)	0.019
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.019
Tnf	tumor necrosis factor	0.019
Prkca	protein kinase C, alpha	0.018
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.018
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.018
Pdcd1	programmed cell death 1	0.018
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.017
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.017
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.017
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.017
Ncoa3	nuclear receptor coactivator 3	0.017
Plcg1	phospholipase C, gamma 1	0.017
Lyz2	lysozyme 2	0.017
Sirpa	signal-regulatory protein alpha	0.017
Sec31a	Sec31 homolog A (S. cerevisiae)	0.017
Dtx1	deltex 1 homolog (Drosophila)	0.016
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.016
Npy1r	neuropeptide Y receptor Y1	0.016
Ahi1	Abelson helper integration site 1	0.016
Lmna	lamin A	0.015
Cd5	CD5 antigen	0.015
Tbx21	T-box 21	0.015
Mtap2	microtubule-associated protein 2	0.015
Creb1	cAMP responsive element binding protein 1	0.015
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.015
Txndc5	thioredoxin domain containing 5	0.015
Cd72	CD72 antigen	0.014
Gsk3b	glycogen synthase kinase 3 beta	0.014
Bcl6	B-cell leukemia/lymphoma 6	0.014
Lat	linker for activation of T cells	0.014
Cd44	CD44 antigen	0.014
Add1	adducin 1 (alpha)	0.014
Dlg2	discs, large homolog 2 (Drosophila)	0.014
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.013
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.013
Man1a2	mannosidase, alpha, class 1A, member 2	0.013
Gna12	guanine nucleotide binding protein, alpha 12	0.013
L1cam	L1 cell adhesion molecule	0.013
Csrp1	cysteine and glycine-rich protein 1	0.013
Btbd10	BTB (POZ) domain containing 10	0.013
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.013
Rap1gap	Rap1 GTPase-activating protein	0.013
Rasal1	RAS protein activator like 1 (GAP1 like)	0.012
Rc3h1	RING CCCH (C3H) domains 1	0.012
Cd80	CD80 antigen	0.012
Nf1	neurofibromatosis 1	0.012
Plp1	proteolipid protein (myelin) 1	0.012
Camk4	calcium/calmodulin-dependent protein kinase IV	0.012
Tagln2	transgelin 2	0.012
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.012
Dgcr2	DiGeorge syndrome critical region gene 2	0.012
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.012
Rac1	RAS-related C3 botulinum substrate 1	0.012
Becn1	beclin 1, autophagy related	0.011
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Syn2	synapsin II	0.011
Shank2	SH3/ankyrin domain gene 2	0.011
Pfkl	phosphofructokinase, liver, B-type	0.011
Pacs2	phosphofurin acidic cluster sorting protein 2	0.010
Syngr1	synaptogyrin 1	0.010
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.010
Capzb	capping protein (actin filament) muscle Z-line, beta	0.010
Resp18	regulated endocrine-specific protein 18	0.010
Ids	iduronate 2-sulfatase	0.010
Gbp6	guanylate binding protein 6	0.010
Il18	interleukin 18	0.010
Kif3b	kinesin family member 3B	0.010